Exposure to 3-Nitropropionic Acid Mitochondrial Toxin Induces Tau Pathology in Tangle-Mouse Model and in Wild Type-Mice

Cilostazol disrupts TLR-4, Akt/GSK-3β/CREB, and IL-6/JAK-2/STAT-3/SOCS-3 crosstalk in a rat model of Huntington's disease

(2018) Hanan El-Abhar et al.   PLoS One

Mitochondria, Oxidative Stress and Innate Immunity

(2018) Yuxin Chen et al.   Frontiers in Physiology

Insulin deficiency results in reversible protein kinase A activation and tau phosphorylation

(2017) Judith M. van der Harg et al.   NEUROBIOLOGY OF DISEASE

Anti-tau antibody administration increases plasma tau in transgenic mice and patients with tauopathy

(2017) Kiran Yanamandra et al.   Science Translational Medicine

Reductions in Amyloid-β-Derived Neuroinflammation, with Minocycline, Restore Cognition but do not Significantly Affect Tau Hyperphosphorylation

(2017) Anna Parachikova et al.   JOURNAL OF ALZHEIMERS DISEASE

Critical data-based re-evaluation of minocycline as a putative specific microglia inhibitor

(2016) Thomas Möller et al.   GLIA

Brain-Wide Insulin Resistance, Tau Phosphorylation Changes, and Hippocampal Neprilysin and Amyloid-  Alterations in a Monkey Model of Type 1 Diabetes

(2016) J. Morales-Corraliza et al.   JOURNAL OF NEUROSCIENCE

Involvement of GSK-3β Phosphorylation Through PI3-K/Akt in Cerebral Ischemia-Induced Neurogenesis in Rats

(2016) Keishi Kisoh et al.   MOLECULAR NEUROBIOLOGY

Reactive microglia drive tau pathology and contribute to the spreading of pathological tau in the brain

(2015) Nicole Maphis et al.   BRAIN

Age- and location-related changes in microglial function

(2015) Rodney M. Ritzel et al.   NEUROBIOLOGY OF AGING

Quercetin Improves Behavioral Deficiencies, Restores Astrocytes and Microglia, and Reduces Serotonin Metabolism in 3-Nitropropionic Acid-Induced Rat Model of Huntington's Disease

(2013) Joy Chakraborty et al.   CNS Neuroscience & Therapeutics

Deconstructing Mitochondrial Dysfunction in Alzheimer Disease

(2013) Vega García-Escudero et al.   Oxidative Medicine and Cellular Longevity

Expression of Tau40 Induces Activation of Cultured Rat Microglial Cells

(2013) Lu Wang et al.   PLoS One

Minocycline alleviates beta-amyloid protein and tau pathology via restraining neuroinflammation induced by diabetic metabolic disorder

(2013) Zhiyou Cai et al.   Clinical Interventions in Aging

Activation of Akt/GSK-3beta/beta-catenin signaling pathway is involved in survival of neurons after traumatic brain injury in rats

(2012) Shangfeng Zhao et al.   NEUROLOGICAL RESEARCH

Tau Promotes Neurodegeneration via DRP1 Mislocalization In Vivo

(2012) Brian DuBoff et al.   NEURON

Adaptive responses to alloxan-induced mild oxidative stress ameliorate certain tauopathy phenotypes

(2011) Yuji Yoshiike et al.   AGING CELL

Administration of 2-arachidonoylglycerol ameliorates both acute and chronic experimental autoimmune encephalomyelitis

(2011) Athanasios Lourbopoulos et al.   BRAIN RESEARCH

Behavioral deficit, oxidative stress, and mitochondrial dysfunction precede tau pathology in P301S transgenic mice

(2011) Magali Dumont et al.   FASEB JOURNAL

Modulation of oxidative stress and tau phosphorylation by the mTOR activator phosphatidic acid in SH-SY5Y cells

(2011) Mariko Taga et al.   FEBS LETTERS

Moderate Environmental Enrichment Mitigates Tauopathy in a Neurofibrillary Tangle Mouse Model

(2011) Inbal Lahiani-Cohen et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Haloperidol causes cytoskeletal collapse in N1E-115 cells through tau hyperphosphorylation induced by oxidative stress: Implications for neurodevelopment

(2010) Gloria Benítez-King et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Effects of mitochondrial dysfunction on the immunological properties of microglia

(2010) Annette I Ferger et al.   Journal of Neuroinflammation

Regulation of Tau Pathology by the Microglial Fractalkine Receptor

(2010) Kiran Bhaskar et al.   NEURON

Regulation of GSK-3β by calpain in the 3-nitropropionic acid model

(2009) N. Crespo-Biel et al.   HIPPOCAMPUS

Statins Reduce the Neurofibrillary Tangle Burden in a Mouse Model of Tauopathy

(2009) Moran Boimel et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Combined expression of tau and the Harlequin mouse mutation leads to increased mitochondrial dysfunction, tau pathology and neurodegeneration

(2009) Luka Kulic et al.   NEUROBIOLOGY OF AGING

Oxidative Stress Signaling in Alzheimers Disease

(2008) B. Su et al.   Current Alzheimer Research

A novel transgenic mouse expressing double mutant tau driven by its natural promoter exhibits tauopathy characteristics

(2008) Hanna Rosenmann et al.   EXPERIMENTAL NEUROLOGY

Minocycline reduces the development of abnormal tau species in models of Alzheimer’s disease

(2008) Wendy Noble et al.   FASEB JOURNAL

Age-Dependent Neurodegeneration Accompanying Memory Loss in Transgenic Mice Defective in Mitochondrial Aldehyde Dehydrogenase 2 Activity

(2008) I. Ohsawa et al.   JOURNAL OF NEUROSCIENCE

N-Acetyl-l-cysteine protects SHSY5Y neuroblastoma cells from oxidative stress and cell cytotoxicity: effects on β-amyloid secretion and tau phosphorylation

(2003) G. Olivieri et al.   JOURNAL OF NEUROCHEMISTRY