Article
Public, Environmental & Occupational Health
Tomi Akinyemiju, Kemi Ogunsina, Anjali Gupta, Iris Liu, Dejana Braithwaite, Robert A. Hiatt
Summary: Cancer burden is increasing globally, especially in low- and middle-income countries. These countries lack comprehensive cancer control programs and funding, therefore primary, secondary, and tertiary prevention strategies are needed to reduce the cancer burden.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Cardiac & Cardiovascular Systems
Andrew E. Moran, Reena Gupta
Summary: In 2017, WHO and Resolve to Save Lives collaborated with country governments to implement the WHO HEARTS hypertension services package in 32 low- and middle-income countries. By 2022, the program treated 12.2 million patients in 165,000 primary care facilities. Facility-based control improved significantly with the use of a digital health information system. However, population-based hypertension control rates remained relatively low.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Review
Urology & Nephrology
Robert Kalyesubula, Andrea L. Conroy, Viviane Calice-Silva, Vivek Kumar, Ugochi Onu, Anthony Batte, Francoise Folefack Kaze, June Fabian, Ifeoma Ulasi
Summary: Kidney disease is a significant cause of death worldwide, particularly in low- and middle-income countries. Improving screening for chronic kidney disease (CKD) is crucial to prevent its progression and reduce the need for kidney replacement therapy. However, there is a lack of data and evidence on CKD screening strategies in these countries, highlighting the need for further research and interventions to address this issue.
SEMINARS IN NEPHROLOGY
(2023)
Review
Medicine, General & Internal
Nicholas P. Oliphant, Samuel Manda, Karen Daniels, Willem A. Odendaal, Donela Besada, Mary Kinney, Emily White Johansson, Tanya Doherty
Summary: The integrated community case management (iCCM) strategy has shown some improvement in the coverage of appropriate treatment for childhood illnesses in children under five years of age, but has not shown a significant impact on neonatal mortality. Further research is needed, particularly on infant and under-five mortality rates and quality of care.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2021)
Editorial Material
Oncology
PhuongThao D. Le, Carolyn Taylor, Anna Cabanes, Huong Thanh Thi Tran
Summary: The global burden of cancer disproportionately affects low- and middle-income countries, where there are critical gaps in supportive care services. By adapting a widely used cancer peer mentoring model to the Vietnamese context using the Cultural Adaptation Framework, adjustments were made to ensure the program is culturally appropriate. This approach can inform future efforts to adapt successful programs to different cultural contexts, making sure they are acceptable and relevant to the local community and setting.
SUPPORTIVE CARE IN CANCER
(2022)
Article
Economics
So Yoon Sim, Elizabeth Watts, Dagna Constenla, Shuoning Huang, Logan Brenzel, Bryan N. Patenaude
Summary: From 2011 to 2030, the total aggregate cost of immunization programs for ten vaccines in 94 low- and middle-income countries is estimated to be between $70.8 billion and $84.1 billion, with costs increasing over the two decades. The relative proportion of vaccine and delivery costs for certain vaccines like pneumococcal conjugate, human papillomavirus, and rotavirus vaccines is expected to increase as more countries introduce these vaccines. Moreover, uncertainty in vaccine prices for some self-financing countries could lead to total costs that are significantly higher than the base case scenario.
Article
Medicine, General & Internal
Guy Frija, Dina H. Salama, Michael G. Kawooya, Bibb Allen
Summary: The concept of primary healthcare is crucial in LMICs for enhancing access to healthcare services. Technological and infrastructure advancements are making POCI more feasible in LMICs. A POCI model is often the only way to provide timely access to imaging care in LMICs. Bringing advanced imaging tools to the POCI will be necessary to address the growing burden of non-communicable diseases. Tailored strategies for training, safety, and quality will be of utmost importance.
Article
Multidisciplinary Sciences
Guanghua Chi, Han Fang, Sourav Chatterjee, Joshua E. Blumenstock
Summary: This research develops microestimates of wealth and poverty distribution at a fine resolution for low- and middle-income countries. These estimates are based on machine learning algorithms applied to various data sources including satellites, mobile phone networks, and Facebook. The estimates are provided for free to facilitate targeted policy response to the COVID-19 pandemic and support sustainable development.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Multidisciplinary Sciences
Shireen Assaf, Lwendo Moonzwe Davis
Summary: This study examines the level and distribution of unrealized fertility in low and middle-income countries across three geographical regions. The findings indicate that unrealized fertility is highest in Western and Central Africa and decreases with an increasing number of children. Factors such as education, wealth quintile, and contraceptive use are associated with decreased unrealized fertility.
Review
Pediatrics
Lydia E. Roberts, Amrit Kaur, Jennie Jewitt-Harris, Andrew Ready, David V. Milford
Summary: Pediatric kidney failure is a global issue that has a significant impact on children's health and mortality. Transplantation is the gold-standard treatment, but it is limited in low- and middle-income countries. Transplant Links Community (TLC), a UK-based charity, provides mentorship and training to units in LMICs to help them establish kidney transplantation services for children. This review summarizes TLC's first-hand experience, challenges, and ongoing barriers in developing pediatric kidney transplantation services in LMICs over the past 15 years.
PEDIATRIC NEPHROLOGY
(2023)
Review
Infectious Diseases
David Musoke, Edwinah Atusingwize, Carol Namata, Rawlance Ndejjo, Rhoda K. Wanyenze, Moses R. Kamya
Summary: Integrated malaria prevention, through the use of multiple prevention methods, has been effective in reducing malaria infection and mosquito density, although some studies have shown mixed results or no clear benefits.
Article
Immunology
Caroline E. Boeke, Lindsey Hiebert, Imam Waked, Tengiz Tsertsvadze, Lali Sharvadze, Maia Butsashvili, Mamuka Zakalashvili, Win Naing, Neil Gupta, Fredrick Kateera, Craig McClure, John W. Ward, Christian B. Ramers
Summary: Access to recommended second-line treatments for patients who fail initial HCV therapy is limited in low- and middle-income countries. However, a pooled analysis of national program data in Egypt, Georgia, and Myanmar showed SVR rates exceeding 90% for alternative retreatment regimens.
CLINICAL INFECTIOUS DISEASES
(2022)
Review
Urology & Nephrology
Muhammad Z. Aslam, Matthew Trail, Ayun K. Cassell, Abdul B. Khan, Steven Payne
Summary: The dynamics of disease prevalence and healthcare systems are changing dramatically in low- and middle-income countries due to factors such as an ageing population, increasing life expectancy, and the rise of non-communicable diseases. The weak healthcare systems are further burdened by low financial budgets, political conflicts, civil war, and the continuing burden of communicable diseases.
Review
Oncology
Andrew Donkor, Vivian Della Atuwo-Ampoh, Frederick Yakanu, Eric Torgbenu, Edward Kwabena Ameyaw, Doris Kitson-Mills, Verna Vanderpuye, Kofi Adesi Kyei, Samuel Anim-Sampong, Omar Khader, Jamal Khader
Summary: In low- and middle-income countries, cancer patients generally face high financial toxicity, with patients from larger households, undergoing multiple cycles of chemotherapy, and seeking treatment at private health facilities experiencing higher financial toxicity. Studies have paid little attention to subjective measures of financial toxicity, indicating a need for further rigorous research.
SUPPORTIVE CARE IN CANCER
(2022)
Review
Oncology
Anna Cabanes, Carolyn Taylor, Carly Malburg, Phuong Thao D. Le
Summary: This scoping review aimed to assess the type of supportive care interventions for cancer patients across the cancer care continuum in low-and middle-income countries (LMICs). The findings suggest that providing different types of supportive services in less-resourced settings, even when health systems are fragmented and fragile, can improve the mental and physical health as well as the quality of life (QoL) of cancer patients.
SUPPORTIVE CARE IN CANCER
(2022)
