Impact of Mucin on Drug Diffusion: Development of a Straightforward In Vitro Method for the Determination of Drug Diffusivity in the Presence of Mucin
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Title
Impact of Mucin on Drug Diffusion: Development of a Straightforward In Vitro Method for the Determination of Drug Diffusivity in the Presence of Mucin
Authors
Keywords
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Journal
Pharmaceutics
Volume 12, Issue 2, Pages 168
Publisher
MDPI AG
Online
2020-02-25
DOI
10.3390/pharmaceutics12020168
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Note: Only part of the references are listed.- Mimicking regional and fasted/fed state conditions in the intestine with the mucus-PVPA in vitro model: The impact of pH and simulated intestinal fluids on drug permeability
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- Optimising the release rate of naproxen liqui-pellet: a new technology for emerging novel oral dosage form
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- A novel microfluidic mucus-chip for studying the permeation of compounds over the mucus barrier
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- The role of mucus on drug transport and its potential to affect therapeutic outcomes
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- Mucus models to evaluate the diffusion of drugs and particles
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- Mucus-PVPA (mucus Phospholipid Vesicle-based Permeation Assay): An artificial permeability tool for drug screening and formulation development
- (2018) Margherita Falavigna et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Experimental Determination of Drug Diffusion Coefficients in Unstirred Aqueous Environments by Temporally Resolved Concentration Measurements
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- Thiolated polymers as mucoadhesive drug delivery systems
- (2017) Sarah Duggan et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Biomimetic PVPA in vitro model for estimation of the intestinal drug permeability using fasted and fed state simulated intestinal fluids
- (2015) Elenaz Naderkhani et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Methods to determine the interactions of micro- and nanoparticles with mucus
- (2015) Julia Grießinger et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Mucus models to evaluate nanomedicines for diffusion
- (2014) Anne-Claire Groo et al. DRUG DISCOVERY TODAY
- Drug “supersaturation” states induced by polymeric micelles and liposomes: A mechanistic investigation into permeability enhancements
- (2013) Massimiliano di Cagno et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Mucus as a barrier to lipophilic drugs
- (2013) Hakon H. Sigurdsson et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- BDDCS Applied to Over 900 Drugs
- (2011) Leslie Z. Benet et al. AAPS Journal
- PGSE-NMR and SANS Studies of the Interaction of Model Polymer Therapeutics with Mucin
- (2009) Peter Charles Griffiths et al. BIOMACROMOLECULES
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