Journal
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL
Volume 18, Issue -, Pages 482-500Publisher
ELSEVIER
DOI: 10.1016/j.csbj.2020.02.009
Keywords
Evolution; Metabolism; Plants; Genomics; Selection; Adaptation
Funding
- EU Horizon 2020 Research and Innovation Programme, project PlantaSYST (SGA-CSA under FPA) [739582, 664620]
- Max-Planck Society
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The origin of primordial metabolism and its expansion to form the metabolic networks extant today represent excellent systems to study the impact of natural selection and the potential adaptive role of novel compounds. Here we present the current hypotheses made on the origin of life and ancestral metabolism and present the theories and mechanisms by which the large chemical diversity of plants might have emerged along evolution. In particular, we provide a survey of statistical methods that can be used to detect signatures of selection at the gene and population level, and discuss potential and limits of these methods for investigating patterns of molecular adaptation in plant metabolism. (C) 2020 The Authors. Published by Elsevier B.V. on behalf of Research Network of Computational and Structural Biotechnology.
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