Article
Plant Sciences
Irina Kneuper, William Teale, Jonathan Edward Dawson, Ryuji Tsugeki, Eleni Katifori, Klaus Palme, Franck Anicet Ditengou
Summary: This study reveals a synergistic relationship between auxin biosynthesis and cellular auxin efflux in leaf vein development, explaining the formation of midvein morphology through computational modeling. The findings suggest that the site-specific accumulation of auxin, regulated by the balanced action of cellular auxin efflux and local auxin biosynthesis, is crucial for leaf vein formation.
JOURNAL OF EXPERIMENTAL BOTANY
(2021)
Article
Biochemistry & Molecular Biology
Pingzhou Du, Yu Liu, Lu Deng, Dong Qian, Xiuhua Xue, Ting Yang, Tonghui Li, Yun Xiang, Haiyun Ren
Summary: The newly discovered AtMAC protein is involved in the regulation of phragmoplast organization during centrifugal phragmoplast expansion, playing a crucial role in cytokinesis.
JOURNAL OF INTEGRATIVE PLANT BIOLOGY
(2023)
Article
Pharmacology & Pharmacy
Santimoy Sen, Sheetal Lagas, Abhishek Roy, Hemant Kumar
Summary: Cells rely on a balanced cytoskeleton to maintain cellular integrity and regulate signaling pathways. Dysregulation of the cytoskeleton can lead to various pathological conditions, and targeting cytoskeletal dynamics may provide new therapeutic approaches for these diseases.
EUROPEAN JOURNAL OF PHARMACOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Daniel A. D. Flormann, Moritz Schu, Emmanuel Terriac, Divyendu Thalla, Lucina Kainka, Marcus Koch, Annica K. B. Gad, Franziska Lautenschlaeger
Summary: Advancements in advanced microscopy techniques have enhanced imaging quality and understanding of subcellular structures, but computational analysis techniques have not progressed at the same pace. A new algorithm for tracing filament networks has been developed, capable of extracting important parameters and distinguishing sub-networks in two-dimensional images. This algorithm can be widely applied in analyzing images obtained from different advanced microscopy methods.
Article
Plant Sciences
Luiz Ricardo dos Santos Tozin, Silvia Rodrigues Machado, Carmen Silvia Fernandes Boaro, Tatiane Maria Rodrigues
Summary: The study investigated the role of cytoskeleton in glandular trichomes of two species of Lamiaceae. The results showed that cytoskeletal polymerization-inhibiting drugs and low levels of Ca2+ led to similar structural alterations in glandular trichomes which can impact secretion release. Further molecular studies are needed to elucidate the role of cytoskeletal elements in the morphogenesis and functioning of glandular trichomes.
Article
Plant Sciences
Jianyan Zeng, Jing Xi, Baoxia Li, Xingying Yan, Yonglu Dai, Yiping Wu, Yuehua Xiao, Yan Pei, Mi Zhang
Summary: This study elucidates the roles of actin and microtubule cytoskeletons in the initiation of cotton fiber growth. Both cytoskeletons align along the growth axis in initiating fibers. Dense and bundled actin filaments (AFs) are observed in fiber cells, while microtubules (MTs) are randomized. Pharmacological experiments demonstrate that depolymerization of both AFs and MTs assist fiber initiation, while AF stabilization and depolymerization inhibit elongation. Notably, the organization of AFs is correlated with MT dynamics.
PLANT CELL REPORTS
(2022)
Article
Multidisciplinary Sciences
Agustina Belen Fernandez Casafuz, Maria Cecilia De Rossi, Luciana Bruno
Summary: By studying the interactions between mitochondria and the cytoskeleton in melanocytes, it was found that microtubules play a major role in organizing mitochondria, while vimentin and actin filaments affect their shape. Microtubules transmit jittering to mitochondria, while F-actin restricts their motion.
SCIENTIFIC REPORTS
(2023)
Article
Chemistry, Multidisciplinary
Ondrej Kucera, Jeremie Gaillard, Christophe Guerin, Clothilde Utzschneider, Manuel Thery, Laurent Blanchoin
Summary: This study investigates the interaction between gliding microtubules and networks of actin filaments, showing that the behavior of microtubules depends on the actin architecture. Unbranched actin networks can effectively guide microtubules during gliding.
Article
Neurosciences
Cristopher Villablanca, Rene Vidal, Christian Gonzalez-Billault
Summary: Astrocytes in the Central Nervous System (CNS) play important roles in both normal functioning and disease. Aging leads to reactive astrogliosis and cellular senescence in astrocytes, resulting in harmful proinflammatory effects. The changes in the cytoskeleton of astrocytes, which have not been extensively studied, may contribute to these alterations associated with aging and pathologies.
BRAIN RESEARCH BULLETIN
(2023)
Review
Plant Sciences
Thomas Dresselhaus, Gerd Juergens
Summary: This review provides a comparative perspective on early zygotic embryogenesis in flowering plants, focusing on processes such as maternal-to-zygotic transition and the establishment of zygotic polarity. Controversial findings regarding the maternal versus paternal contribution to early embryo development are highlighted, along with discussions on major signaling pathways, cell fate genes, and hormones in early embryogenesis. The article also addresses the lack of knowledge about embryo patterning and basic body plan establishment in angiosperms, and discusses the establishment of stem cell niches and the evolutionary aspects of plant embryo development.
ANNUAL REVIEW OF PLANT BIOLOGY, VOL 72, 2021
(2021)
Article
Chemistry, Multidisciplinary
Kodai Fukumoto, Yuya Miyazono, Takuya Ueda, Yoshie Harada, Hisashi Tadakuma
Summary: Cellular transport systems are complex and efficient, and there is a need to design artificial transport systems using nanotechnology. However, the design principles have been difficult to establish due to the lack of understanding on how motor layout affects motile activity. In this study, a DNA origami platform was used to evaluate the effect of motor protein layout on transporter motility. The densely packed layout of kinesin motor protein was found to decrease the run length of the transporter, highlighting the importance of considering steric hindrance in transport system design.
NANOSCALE ADVANCES
(2023)
Article
Biotechnology & Applied Microbiology
Kun Wang, Erlin Gao, Dan Liu, Xiaomeng Wu, Pengwei Wang
Summary: Somatic embryogenesis is an effective method for citrus genetic improvement, and our study found that the remodeling of endomembrane systems and cytoskeleton plays an important role in citrus SE.
PLANT CELL TISSUE AND ORGAN CULTURE
(2022)
Article
Multidisciplinary Sciences
Stefan Baar, Masahiro Kuragano, Kiyotaka Tokuraku, Shinya Watanabe
Summary: This study aims to define a comprehensive approach to quantitatively estimate the physical cell activity based on migration and morphology using statistical analysis. The researchers present quantitative measurements of the influence of drugs on cell populations and have developed a customized deep learning cell detection and tracking procedure.
SCIENTIFIC REPORTS
(2022)
Review
Endocrinology & Metabolism
Nicole R. Gould, Olivia M. Torre, Jenna M. Leser, Joseph P. Stains
Summary: Bone is a mechano-responsive tissue that adapts to changes in its mechanical environment. Mechanical stress is crucial for bone mass and quality regulation, and understanding how bone cells sense and transduce these mechanical cues is important. While individual cytoskeletal components have been identified as mechano-sensors in bone, the interconnectedness and collaboration of the entire cytoskeleton may be essential for proper bone cell mechano-transduction.
Review
Cell Biology
Anne-Betty Ndiaye, Gijsje H. Koenderink, Michal Shemesh
Summary: The mammalian cytoskeleton plays an important role in transmitting external forces to the cell interior and generating intracellular forces. The three interpenetrating structural proteins, actin, microtubules, and intermediate filaments, have interdependent functions and the intermediate filaments play a central role in mechanosensitivity. Cytoskeletal crosstalk regulates the stability and organization of all three filament families at different scales, and also affects cell adaptation to external cues.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2022)
Article
Plant Sciences
Aneta Zabka, Justyna Teresa Polit, Konrad Winnicki, Patrycja Paciorek, Jolanta Juszczak, Mateusz Nowak, Janusz Maszewski
PLANT CELL REPORTS
(2016)
Article
Plant Sciences
Aneta Zabka, Konrad Winnicki, Justyna Teresa Polit, Janusz Maszewski
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2017)
Article
Biochemistry & Molecular Biology
Konrad Winnicki, Justyna Teresa Polit, Aneta Zabka, Janusz Maszewski
Article
Plant Sciences
Konrad Winnicki, Aneta Zabka, Justyna Teresa Polit, Janusz Maszewski
Article
Plant Sciences
Agnieszka Chmielnicka, Aneta Zabka, Konrad Winnicki, Janusz Maszewski, Justyna Teresa Polit
PLANT CELL REPORTS
(2018)
Article
Plant Sciences
Konrad Winnicki, Iwona Ciereszko, Joanna Lesniewska, Alina T. Dubis, Anna Basa, Aneta Zabka, Marcin Holota, Lukasz Sobiech, Agnieszka Faligowska, Grzegorz Skrzypczak, Janusz Maszewski, Justyna T. Polit
Article
Biochemistry & Molecular Biology
Justyna T. Polit, Iwona Ciereszko, Alina T. Dubis, Joanna Lesniewska, Anna Basa, Konrad Winnicki, Aneta Zabka, Marharyta Audzei, Lukasz Sobiech, Agnieszka Faligowska, Grzegorz Skrzypczak, Janusz Maszewski
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2019)
Article
Plant Sciences
Aneta Zabka, Konrad Winnicki, Justyna Teresa Polit, Joanna Bernasinska-Slomczewska, Janusz Maszewski
PLANT CELL REPORTS
(2020)
Article
Multidisciplinary Sciences
Konrad Winnicki, Katarzyna Ludzik, Aneta Zabka, Justyna Teresa Polit, Anna Zawisza, Janusz Maszewski
Summary: Gemini surfactants have low environmental impact and may serve as a promising solution to reduce algal blooms in water systems. The toxic effects of a specific gemini surfactant on Chlorella cells were investigated, showing dose-dependent cell death and a potential mechanism targeting the photosynthetic apparatus. These findings suggest that gemini surfactants could effectively control algal growth and adhesion in aquatic environments.
SCIENTIFIC REPORTS
(2021)
Review
Cell Biology
Konrad Winnicki, Justyna Teresa Polit, Aneta Zabka, Janusz Maszewski
Summary: Plasmodesmata play crucial roles in intercellular transport, but high permeability may affect the establishment of auxin maxima. Disrupting the symplastic continuum is necessary for inducing or completing certain developmental processes. Research focuses on auxin-dependent regulation of plasmodesmata function, potentially participating in gene expression by altering permeability.
Article
Cell Biology
Aneta Zabka, Konrad Winnicki, Justyna Teresa Polit, Mateusz Wroblewski, Janusz Maszewski
Summary: The toxicity of cadmium to plant cells is mainly mediated by the generation of ROS and DNA damage-induced replication stress, ultimately activating signaling factors involved in cell cycle control pathways, DNA repair systems, and epigenetic adaptations.
Article
Biochemistry & Molecular Biology
Pawel Szczeblewski, Witold Andralojc, Justyna Polit, Aneta Zabka, Konrad Winnicki, Tomasz Laskowski
Summary: Through detailed NMR-driven stereochemical studies, the absolute configuration of all stereogenic centers of mepartricins A and B was defined, and they were shown to be structurally identical to the main components of the aureofacin complex.
Article
Cell Biology
Aneta Zabka, Natalia Gocek, Konrad Winnicki, Pawel Szczeblewski, Tomasz Laskowski, Justyna Teresa Polit
Summary: The experiments on Vicia faba root meristem cells exposed to 150 mu M cadmium chloride analyzed the epigenetic changes, specifically focusing on DNA replication stress. The findings revealed a significant decrease in H3K79Me2 levels in CdCl2-treated interphase cell nuclei, along with an increase in H3K56Ac histone foci, a variety of nuclear and nucleolar labeling patterns, and a decrease in DNA methylation. These changes indicate the important role of DNA and histone modifications in gene expression and plant development under cadmium-induced stress conditions.
Review
Medicine, Research & Experimental
Agnieszka Chmielnicka, Aneta Zabka, Konrad Winnicki, Justyna Teresa Polit
POSTEPY HIGIENY I MEDYCYNY DOSWIADCZALNEJ
(2017)
