Degradation of the Tumor Suppressor PDCD4 Is Impaired by the Suppression of p62/SQSTM1 and Autophagy

Autophagy in liver diseases: Time for translation?

(2019) Manon Allaire et al.   JOURNAL OF HEPATOLOGY

Control Mechanisms of the Tumor Suppressor PDCD4: Expression and Functions

(2019) Sachiko Matsuhashi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Autophagy Function and Dysfunction: Potential Drugs as Anti-Cancer Therapy

(2019) Francesca Cuomo et al.   Cancers

PDCD4 Is an Androgen-Repressed Tumor Suppressor that Regulates Prostate Cancer Growth and Castration Resistance

(2018) Kenji Zennami et al.   MOLECULAR CANCER RESEARCH

Regulation of selective autophagy: the p62/SQSTM1 paradigm

(2017) Trond Lamark et al.   Essays in Biochemistry

Tumor suppressor Pdcd4 attenuates Sin1 translation to inhibit invasion in colon carcinoma

(2017) Q Wang et al.   ONCOGENE

Molecular mechanisms and physiological roles of Atg5/Atg7-independent alternative autophagy

(2017) Satoko ARAKAWA et al.   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

miR-23a/b promote tumor growth and suppress apoptosis by targeting PDCD4 in gastric cancer

(2017) Xiuting Hu et al.   Cell Death & Disease

Chaperone-mediated autophagy compensates for impaired macroautophagy in the cirrhotic liver to promote hepatocellular carcinoma

(2017) Srinivas Chava et al.   Oncotarget

Inhibition of autophagy with bafilomycin and chloroquine decreases mitochondrial quality and bioenergetic function in primary neurons

(2017) Matthew Redmann et al.   Redox Biology

TGF-â1-induced miR-503 controls cell growth and apoptosis by targeting PDCD4 in glioblastoma cells

(2017) Pin Guo et al.   Scientific Reports

Proliferation, survival and metabolism: the role of PI3K/AKT/mTOR signalling in pluripotency and cell fate determination

(2016) Jason S. L. Yu et al.   DEVELOPMENT

The ATG conjugation systems are important for degradation of the inner autophagosomal membrane

(2016) Kotaro Tsuboyama et al.   SCIENCE

p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming

(2016) Tetsuya Saito et al.   Nature Communications

Reliable LC3 and p62 autophagy marker detection in formalin fixed paraffin embedded human tissue by immunohistochemistry

(2015) A.M. Schläfli et al.   EUROPEAN JOURNAL OF HISTOCHEMISTRY

The role for autophagy in cancer

(2015) Eileen White   JOURNAL OF CLINICAL INVESTIGATION

LC3- and p62-based biochemical methods for the analysis of autophagy progression in mammalian cells

(2015) Peidu Jiang et al.   METHODS

Autophagosome–lysosome fusion is independent of V-ATPase-mediated acidification

(2015) Caroline Mauvezin et al.   Nature Communications

Tumor suppressor PDCD4 inhibits NF-κB-dependent transcription in human glioblastoma cells by direct interaction with p65

(2014) Soon-Kyung Hwang et al.   CARCINOGENESIS

p62/SQSTM1 synergizes with autophagy for tumor growth in vivo

(2014) H. Wei et al.   GENES & DEVELOPMENT

Bafilomycin A1 targets both autophagy and apoptosis pathways in pediatric B-cell acute lymphoblastic leukemia

(2014) N. Yuan et al.   HAEMATOLOGICA

A dual role for autophagy in a murine model of lung cancer

(2014) Shuan Rao et al.   Nature Communications

Control of a tumor suppressor PDCD4: Degradation mechanisms of the protein in hepatocellular carcinoma cells

(2013) Sachiko Matsuhashi et al.   CELLULAR SIGNALLING

MicroRNA-182 promotes cell growth, invasion, and chemoresistance by targeting programmed cell death 4 (PDCD4) in human ovarian carcinomas

(2013) Yu-Quan Wang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Tumor suppressor PDCD4 modulates miR-184-mediated direct suppression of C-MYC and BCL2 blocking cell growth and survival in nasopharyngeal carcinoma

(2013) Yan Zhen et al.   Cell Death & Disease

Tumor Suppressor PDCD4 Represses Internal Ribosome Entry Site-Mediated Translation of Antiapoptotic Proteins and Is Regulated by S6 Kinase 2

(2012) U. Liwak et al.   MOLECULAR AND CELLULAR BIOLOGY

p62 Stages an Interplay Between the Ubiquitin-Proteasome System and Autophagy in the Heart of Defense Against Proteotoxic Stress

(2012) Huabo Su et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Role of AMPK-mTOR-Ulk1/2 in the Regulation of Autophagy: Cross Talk, Shortcuts, and Feedbacks

(2011) S. Alers et al.   MOLECULAR AND CELLULAR BIOLOGY

Pdcd4 directly binds the coding region of c-myb mRNA and suppresses its translation

(2011) P Singh et al.   ONCOGENE

Regulation of tumor suppressor PDCD4 by novel protein kinase C isoforms

(2010) Mayumi Nakashima et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Fighting disease by selective autophagy of aggregate-prone proteins

(2010) Helene Knaevelsrud et al.   FEBS LETTERS

Physiological significance of selective degradation of p62 by autophagy

(2010) Masaaki Komatsu et al.   FEBS LETTERS

Autophagy facilitates glycolysis during Ras-mediated oncogenic transformation

(2010) Rebecca Lock et al.   MOLECULAR BIOLOGY OF THE CELL

Termination of autophagy and reformation of lysosomes regulated by mTOR

(2010) Li Yu et al.   NATURE

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

(2010) Sven Geisler et al.   NATURE CELL BIOLOGY

MicroRNA-21 promotes cell proliferation and down-regulates the expression of programmed cell death 4 (PDCD4) in HeLa cervical carcinoma cells

(2009) Qing Yao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Programmed Cell Death Protein 4 Down-regulates Y-Box Binding Protein-1 Expression via a Direct Interaction with Twist1 to Suppress Cancer Cell Growth

(2009) M. Shiota et al.   CANCER RESEARCH

Autophagy and metastasis: another double-edged sword

(2009) Candia M Kenific et al.   CURRENT OPINION IN CELL BIOLOGY

Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy

(2009) Nao Hosokawa et al.   MOLECULAR BIOLOGY OF THE CELL

ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery

(2009) Chang Hwa Jung et al.   MOLECULAR BIOLOGY OF THE CELL

Discovery of Atg5/Atg7-independent alternative macroautophagy

(2009) Yuya Nishida et al.   NATURE

Crystal structure of the eIF4A-PDCD4 complex

(2009) J. H. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Translation Inhibitor Pdcd4 Is Targeted for Degradation during Tumor Promotion

(2008) T. Schmid et al.   CANCER RESEARCH

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Autophagosome-Independent Essential Function for the Autophagy Protein Atg5 in Cellular Immunity to Intracellular Pathogens

(2008) Zijiang Zhao et al.   Cell Host & Microbe

IGF-I, EGF, and sex steroids regulate autophagy in bovine mammary epithelial cells via the mTOR pathway

(2008) Agnieszka Sobolewska et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells

(2008) Taichi Hara et al.   JOURNAL OF CELL BIOLOGY

PDCD4gene silencing in gliomas is associated with 5′CpG island methylation and unfavourable prognosis

(2008) Fei Gao et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE

PDCD4 inhibits translation initiation by binding to eIF4A using both its MA3 domains

(2008) C. Suzuki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA