Rewiring of Lipid Metabolism and Storage in Ovarian Cancer Cells after Anti-VEGF Therapy

Adipocyte and lipid metabolism in cancer drug resistance

(2019) Yihai Cao   JOURNAL OF CLINICAL INVESTIGATION

Synthesis, biological activities, and docking studies of d-pantolactone derivatives as novel FAS inhibitors

(2019) Hua Fang et al.   BIOORGANIC & MEDICINAL CHEMISTRY

The challenges and promise of targeting the Liver X Receptors for treatment of inflammatory disease

(2018) Michael B. Fessler   PHARMACOLOGY & THERAPEUTICS

Lysophosphatidylcholine acyltransferase 2-mediated lipid droplet production supports colorectal cancer chemoresistance

(2018) Alexia Karen Cotte et al.   Nature Communications

Histone variant macroH2A1 rewires carbohydrate and lipid metabolism of hepatocellular carcinoma cells towards cancer stem cells

(2018) Oriana Lo Re et al.   Epigenetics

Integration of MRI and MRS approaches to monitor molecular imaging and metabolomic effects of trabectedin on a preclinical ovarian cancer model

(2018) Rossella Canese et al.   NMR IN BIOMEDICINE

AMPK: Mechanisms of Cellular Energy Sensing and Restoration of Metabolic Balance

(2017) Daniel Garcia et al.   MOLECULAR CELL

HIF drives lipid deposition and cancer in ccRCC via repression of fatty acid metabolism

(2017) Weinan Du et al.   Nature Communications

Acidosis Drives the Reprogramming of Fatty Acid Metabolism in Cancer Cells through Changes in Mitochondrial and Histone Acetylation

(2016) Cyril Corbet et al.   Cell Metabolism

The Complexity of Translating Anti-angiogenesis Therapy from Basic Science to the Clinic

(2016) Weilan Ye   DEVELOPMENTAL CELL

Antiangiogenic therapy in oncology: current status and future directions

(2016) Gordon C Jayson et al.   LANCET

Bevacizumab in ovarian cancer: A critical review of phase III studies

(2016) Luigi Rossi et al.   Oncotarget

Acetyl-CoA Synthetase 2 Promotes Acetate Utilization and Maintains Cancer Cell Growth under Metabolic Stress

(2015) Zachary T. Schug et al.   CANCER CELL

Uncoupling Nuclear Receptor LXR and Cholesterol Metabolism in Cancer

(2015) Fabiola Bovenga et al.   Cell Metabolism

Metabolic and hypoxic adaptation to anti-angiogenic therapy: a target for induced essentiality

(2015) A. McIntyre et al.   EMBO Molecular Medicine

Famine versus feast: understanding the metabolism of tumors in vivo

(2015) Jared R. Mayers et al.   TRENDS IN BIOCHEMICAL SCIENCES

HIF2 -Dependent Lipid Storage Promotes Endoplasmic Reticulum Homeostasis in Clear-Cell Renal Cell Carcinoma

(2015) B. Qiu et al.   Cancer Discovery

Cancer stem cells from epithelial ovarian cancer patients privilege oxidative phosphorylation, and resist glucose deprivation

(2015) Anna Pastò et al.   Oncotarget

Prognostic significance of AMPK activation in advanced stage colorectal cancer treated with chemotherapy plus bevacizumab

(2014) E Zulato et al.   BRITISH JOURNAL OF CANCER

VEGF-Targeted Therapy Stably Modulates the Glycolytic Phenotype of Tumor Cells

(2014) M. Curtarello et al.   CANCER RESEARCH

Blocking Lipid Synthesis Overcomes Tumor Regrowth and Metastasis after Antiangiogenic Therapy Withdrawal

(2014) Nor Eddine Sounni et al.   Cell Metabolism

Hypoxia, lipids, and cancer: surviving the harsh tumor microenvironment

(2014) Daniel Ackerman et al.   TRENDS IN CELL BIOLOGY

Fatty Acid Uptake and Lipid Storage Induced by HIF-1α Contribute to Cell Growth and Survival after Hypoxia-Reoxygenation

(2014) Karim Bensaad et al.   Cell Reports

Liver X Receptors Inhibit Proliferation of Human Colorectal Cancer Cells and Growth of Intestinal Tumors in Mice

(2013) Giuseppe Lo Sasso et al.   GASTROENTEROLOGY

Dichloroacetate reverses the hypoxic adaptation to bevacizumab and enhances its antitumor effects in mouse xenografts

(2013) Krishan Kumar et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Heterogeneity of tumor-induced gene expression changes in the human metabolic network

(2013) Jie Hu et al.   NATURE BIOTECHNOLOGY

Lipogenesis and lipolysis: The pathways exploited by the cancer cells to acquire fatty acids

(2013) Nousheen Zaidi et al.   PROGRESS IN LIPID RESEARCH

Phospholipids and lipid droplets

(2012) Anke Penno et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Apoptosis-induced mitochondrial dysfunction causes cytoplasmic lipid droplet formation

(2012) J Boren et al.   CELL DEATH AND DIFFERENTIATION

Glycolytic Phenotype and AMP Kinase Modify the Pathologic Response of Tumor Xenografts to VEGF Neutralization

(2011) G. Nardo et al.   CANCER RESEARCH

Bevacizumab impairs oxidative energy metabolism and shows antitumoral effects in recurrent glioblastomas: a 31P/1H MRSI and quantitative magnetic resonance imaging study

(2011) E. Hattingen et al.   NEURO-ONCOLOGY

Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma

(2011) Olivier Keunen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of Phosphatidylcholine Cycle Enzymes in Human Epithelial Ovarian Cancer Cells

(2010) E. Iorio et al.   CANCER RESEARCH

Liver X receptor agonist inhibits proliferation of ovarian carcinoma cells stimulated by oxidized low density lipoprotein

(2009) Daniel R. Scoles et al.   GYNECOLOGIC ONCOLOGY

Hypoxia Inducible Factor-1α Inactivation Unveils a Link between Tumor Cell Metabolism and Hypoxia-Induced Cell Death

(2008) Elena Favaro et al.   AMERICAN JOURNAL OF PATHOLOGY