Inhibition of Alternative Cancer Cell Metabolism of EGFR Mutated Non-Small Cell Lung Cancer Serves as a Potential Therapeutic Strategy

Oxidative Phosphorylation as an Emerging Target in Cancer Therapy

(2018) Thomas M. Ashton et al.   CLINICAL CANCER RESEARCH

Inhibition of monocarboxyate transporter 1 by AZD3965 as a novel therapeutic approach for diffuse large B-cell lymphoma and Burkitt lymphoma

(2017) Richard A. Noble et al.   HAEMATOLOGICA

Mitochondrial markers predict survival and progression in non-small cell lung cancer (NSCLC) patients: Use as companion diagnostics

(2017) Federica Sotgia et al.   Oncotarget

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(2017) Chien-Hua Tseng et al.   Oncotarget

Inhibition of monocarboxyate transporter 1 by AZD3965 as a novel therapeutic approach for diffuse large B-cell lymphoma and Burkitt lymphoma

(2017) Richard A. Noble et al.   HAEMATOLOGICA

Epidermal Growth Factor Receptor Cell Proliferation Signaling Pathways

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The Mitochondrial Complex(I)ty of Cancer

(2017) Félix A. Urra et al.   Frontiers in Oncology

Reexamining cancer metabolism: lactate production for carcinogenesis could be the purpose and explanation of the Warburg Effect

(2016) Iñigo San-Millán et al.   CARCINOGENESIS

Metabolic Heterogeneity in Human Lung Tumors

(2016) Christopher T. Hensley et al.   CELL

Metabolic regulation of mitochondrial dynamics

(2016) Prashant Mishra et al.   JOURNAL OF CELL BIOLOGY

EGFR C797S mutation mediates resistance to third-generation inhibitors in T790M-positive non-small cell lung cancer

(2016) Shuhang Wang et al.   Journal of Hematology & Oncology

Lactate metabolism is associated with mammalian mitochondria

(2016) Ying-Jr Chen et al.   Nature Chemical Biology

MCT1 Modulates Cancer Cell Pyruvate Export and Growth of Tumors that Co-express MCT1 and MCT4

(2016) Candice Sun Hong et al.   Cell Reports

Global Cancer Incidence and Mortality Rates and Trends--An Update

(2015) L. A. Torre et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Targeting mitochondria metabolism for cancer therapy

(2015) Samuel E Weinberg et al.   Nature Chemical Biology

EGFR and NF-κB: partners in cancer

(2015) Kateryna Shostak et al.   TRENDS IN MOLECULAR MEDICINE

Mitochondrial translocation of EGFR regulates mitochondria dynamics and promotes metastasis in NSCLC

(2015) Ting-Fang Che et al.   Oncotarget

Warburg Effect or Reverse Warburg Effect? A Review of Cancer Metabolism

(2015) Xiao Dong Xu et al.   Oncology Research and Treatment

Pyruvate Dehydrogenase Kinases: Therapeutic Targets for Diabetes and Cancers

(2015) Nam Ho Jeoung   Diabetes & Metabolism Journal

Characterization of monocarboxylate transporters (MCTs) expression in soft tissue sarcomas: distinct prognostic impact of MCT1 sub-cellular localization

(2014) Céline Pinheiro et al.   Journal of Translational Medicine

Comprehensive measurement of respiratory activity in permeabilized cells using extracellular flux analysis

(2014) Joshua K Salabei et al.   Nature Protocols

PDK1 inhibition is a novel therapeutic target in multiple myeloma

(2013) S Fujiwara et al.   BRITISH JOURNAL OF CANCER

Activity of the Monocarboxylate Transporter 1 Inhibitor AZD3965 in Small Cell Lung Cancer

(2013) R. Polanski et al.   CLINICAL CANCER RESEARCH

Targeting lactate metabolism for cancer therapeutics

(2013) Joanne R. Doherty et al.   JOURNAL OF CLINICAL INVESTIGATION

Lung Cancer and Prognosis in Taiwan: A Population-Based Cancer Registry

(2013) Bing-Yen Wang et al.   Journal of Thoracic Oncology

Suppression of Mitochondrial Complex I Influences Cell Metastatic Properties

(2013) Xuelian He et al.   PLoS One

Mechanism for activation of mutated epidermal growth factor receptors in lung cancer

(2013) M. Red Brewer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anti-mitochondrial therapy in human breast cancer multi-cellular spheroids

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Celastrol targets mitochondrial respiratory chain complex I to induce reactive oxygen species-dependent cytotoxicity in tumor cells

(2011) Guozhu Chen et al.   BMC CANCER

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

The reverse Warburg effect: Aerobic glycolysis in cancer associated fibroblasts and the tumor stroma

(2011) Stephanos Pavlides et al.   CELL CYCLE

Nuclear Translocation of Epidermal Growth Factor Receptor by Akt-dependent Phosphorylation Enhances Breast Cancer-resistant Protein Expression in Gefitinib-resistant Cells

(2011) Wei-Chien Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial DNA mutations in respiratory complex-I in never-smoker lung cancer patients contribute to lung cancer progression and associated withEGFRgene mutation

(2011) Santanu Dasgupta et al.   JOURNAL OF CELLULAR PHYSIOLOGY

EGFR and EGFRvIII undergo stress- and EGFR kinase inhibitor-induced mitochondrial translocalization: A potential mechanism of EGFR-driven antagonism of apoptosis

(2011) Xinyu Cao et al.   Molecular Cancer

Oligomycin-induced Bioenergetic Adaptation in Cancer Cells with Heterogeneous Bioenergetic Organization

(2010) Wenshan Hao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel Epidermal Growth Factor Receptor Mutation-Specific Antibodies for Non-small Cell Lung Cancer: Immunohistochemistry as a Possible Screening Method for Epidermal Growth Factor Receptor Mutations

(2010) Yasufumi Kato et al.   Journal of Thoracic Oncology

Epidermal Growth Factor Receptor Translocation to the Mitochondria

(2009) Michelle L. Demory et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nuclear EGFR contributes to acquired resistance to cetuximab

(2009) C Li et al.   ONCOGENE