Novel and Rare Fusion Transcripts Involving Transcription Factors and Tumor Suppressor Genes in Acute Myeloid Leukemia

Genomic subtyping and therapeutic targeting of acute erythroleukemia

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CNOT2 promotes proliferation and angiogenesis via VEGF signaling in MDA-MB-231 breast cancer cells

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Detection of recurrent and of novel fusion transcripts in myeloid malignancies by targeted RNA sequencing

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The genetic basis and cell of origin of mixed phenotype acute leukaemia

(2018) Thomas B. Alexander et al.   NATURE

Aneuploid acute myeloid leukemia exhibits a signature of genomic alterations in the cell cycle and protein degradation machinery

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Genetic Basis of Acute Lymphoblastic Leukemia

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The T-ALL related gene BCL11B regulates the initial stages of human T-cell differentiation

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TumorFusions: an integrative resource for cancer-associated transcript fusions

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Complex heatmaps reveal patterns and correlations in multidimensional genomic data

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The EMT transcription factor Zeb2 controls adult murine hematopoietic differentiation by regulating cytokine signaling

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The EMT regulator ZEB2 is a novel dependency of human and murine acute myeloid leukemia

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Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel

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Small Maf proteins (MafF, MafG, MafK): History, structure and function

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Genomic Classification and Prognosis in Acute Myeloid Leukemia

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Enrichr: a comprehensive gene set enrichment analysis web server 2016 update

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Best Practices in Chronic Myeloid Leukemia Monitoring and Management

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Genomic analyses identify recurrent MEF2D fusions in acute lymphoblastic leukaemia

(2016) Zhaohui Gu et al.   Nature Communications

Rawcopy: Improved copy number analysis with Affymetrix arrays

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A novel mouse model identifies cooperating mutations and therapeutic targets critical for chronic myeloid leukemia progression

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Identification of the NUP98-PHF23 fusion gene in pediatric cytogenetically normal acute myeloid leukemia by whole-transcriptome sequencing

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limma powers differential expression analyses for RNA-sequencing and microarray studies

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Structural basis of antizyme-mediated regulation of polyamine homeostasis

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Haploinsufficiency of the c-myc transcriptional repressor FIR, as a dominant negative-alternative splicing model, promoted p53-dependent T-cell acute lymphoblastic leukemia progression by activating Notch1

(2015) Kazuyuki Matsushita et al.   Oncotarget

Novel ZEB2-BCL11B Fusion Gene Identified by RNA-Sequencing in Acute Myeloid Leukemia with t(2;14)(q22;q32)

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Pegasus: a comprehensive annotation and prediction tool for detection of driver gene fusions in cancer

(2014) Francesco Abate et al.   BMC Systems Biology

Integrated genome-wide genotyping and gene expression profiling reveals BCL11B as a putative oncogene in acute myeloid leukemia with 14q32 aberrations

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The landscape and therapeutic relevance of cancer-associated transcript fusions

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Carboxypeptidase-D is elevated in prostate cancer and its anti-apoptotic activity is abolished by combined androgen and prolactin receptor targeting

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NUP98-PHF23 Is a Chromatin-Modifying Oncoprotein That Causes a Wide Array of Leukemias Sensitive to Inhibition of PHD Histone Reader Function

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Oncofuse: a computational framework for the prediction of the oncogenic potential of gene fusions

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SiRNA-targeted carboxypeptidase D inhibits hepatocellular carcinoma growth

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Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia

(2013)   NEW ENGLAND JOURNAL OF MEDICINE

Cytogenetic profile of a large cohort of Tunisian de novo acute myeloid leukemia

(2012) Abir Gmidène et al.   Hematology

Mammalian HCA66 protein is required for both ribosome synthesis and centriole duplication

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New Fusion Transcripts Identified in Normal Karyotype Acute Myeloid Leukemia

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Genomic Hallmarks of Genes Involved in Chromosomal Translocations in Hematological Cancer

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ChimeraScan: a tool for identifying chimeric transcription in sequencing data

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Downregulation of SAV1 plays a role in pathogenesis of high-grade clear cell renal cell carcinoma

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CNOT2 depletion disrupts and inhibits the CCR4-NOT deadenylase complex and induces apoptotic cell death

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deFuse: An Algorithm for Gene Fusion Discovery in Tumor RNA-Seq Data

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The molecular signature of oncofusion proteins in acute myeloid leukemia

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Components of the Hippo pathway cooperate with Nek2 kinase to regulate centrosome disjunction

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Acute mixed lineage leukemia in children: the experience of St Jude Children's Research Hospital

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Cloning and characterization of a novel intracellular protein p48.2 that negatively regulates cell cycle progression

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Loss of the Alox5 gene impairs leukemia stem cells and prevents chronic myeloid leukemia

(2009) Yaoyu Chen et al.   NATURE GENETICS

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Novel IGHα translocations, t(2;14)(q14.3;q32) and t(14;17)(q32;q21), in B-cell precursor acute lymphoblastic leukemia

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Prolactin and Estrogen Up-Regulate Carboxypeptidase-D to Promote Nitric Oxide Production and Survival of MCF-7 Breast Cancer Cells

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