Elevated hepatocyte growth factor expression as an autocrine c-Met activation mechanism in acquired resistance to sorafenib in hepatocellular carcinoma cells
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Title
Elevated hepatocyte growth factor expression as an autocrine c-Met activation mechanism in acquired resistance to sorafenib in hepatocellular carcinoma cells
Authors
Keywords
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Journal
CANCER SCIENCE
Volume 107, Issue 4, Pages 407-416
Publisher
Wiley
Online
2016-01-21
DOI
10.1111/cas.12891
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Related references
Note: Only part of the references are listed.- Sorafenib and DE605, a novel c-Met inhibitor, synergistically suppress hepatocellular carcinoma
- (2015) Xiufeng Jiang et al. Oncotarget
- Microenvironment-Derived HGF Overcomes Genetically Determined Sensitivity to Anti-MET Drugs
- (2014) S. Pennacchietti et al. CANCER RESEARCH
- Cabozantinib Suppresses Tumor Growth and Metastasis in Hepatocellular Carcinoma by a Dual Blockade of VEGFR2 and MET
- (2014) Q. Xiang et al. CLINICAL CANCER RESEARCH
- Inhibition of Akt Reverses the Acquired Resistance to Sorafenib by Switching Protective Autophagy to Autophagic Cell Death in Hepatocellular Carcinoma
- (2014) B. Zhai et al. MOLECULAR CANCER THERAPEUTICS
- The Met receptor tyrosine kinase: A key player in oncogenesis and drug resistance
- (2014) Christiane R. Maroun et al. PHARMACOLOGY & THERAPEUTICS
- Reciprocal Activating Crosstalk between c-Met and Caveolin 1 Promotes Invasive Phenotype in Hepatocellular Carcinoma
- (2014) Peyda Korhan et al. PLoS One
- SC-2001 Overcomes STAT3-mediated Sorafenib Resistance through RFX-1/SHP-1 Activation in Hepatocellular Carcinoma
- (2014) Jung-Chen Su et al. NEOPLASIA
- Targeting Epithelial-to-Mesenchymal Transition with Met Inhibitors Reverts Chemoresistance in Small Cell Lung Cancer
- (2013) I. Canadas et al. CLINICAL CANCER RESEARCH
- PKI-587 and sorafenib alone and in combination on inhibition of liver cancer stem cell proliferation
- (2013) Roberto Gedaly et al. JOURNAL OF SURGICAL RESEARCH
- The Enhanced Metastatic Potential of Hepatocellular Carcinoma (HCC) Cells with Sorafenib Resistance
- (2013) Ariel Ka-Man Chow et al. PLoS One
- Treating hepatocellular carcinoma progression following first-line sorafenib: therapeutic options and clinical observations
- (2013) A. Ruth He et al. Therapeutic Advances in Gastroenterology
- Increased MET and HGF gene copy numbers are associated with trastuzumab failure in HER2-positive metastatic breast cancer
- (2012) G Minuti et al. BRITISH JOURNAL OF CANCER
- Long-term exposure to sorafenib of liver cancer cells induces resistance with epithelial-to-mesenchymal transition, increased invasion and risk of rebound growth
- (2012) Hannah van Malenstein et al. CANCER LETTERS
- Second-Line Therapies in Hepatocellular Carcinoma: Emergence of Resistance to Sorafenib
- (2012) A. Villanueva et al. CLINICAL CANCER RESEARCH
- Role of sorafenib in the treatment of advanced hepatocellular carcinoma: An update
- (2012) Angela Gauthier et al. HEPATOLOGY RESEARCH
- Clinical impact of c-Met expression and its gene amplification in hepatocellular carcinoma
- (2012) Shunsuke Kondo et al. International Journal of Clinical Oncology
- Hepatocellular carcinoma
- (2012) Alejandro Forner et al. LANCET
- Cooperative interaction of MUC1 with the HGF/c-Met pathway during hepatocarcinogenesis
- (2012) Giray Bozkaya et al. Molecular Cancer
- Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion
- (2012) Ravid Straussman et al. NATURE
- Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors
- (2012) Timothy R. Wilson et al. NATURE
- Autocrine activation of the MET receptor tyrosine kinase in acute myeloid leukemia
- (2012) Alex Kentsis et al. NATURE MEDICINE
- Medical therapies for hepatocellular carcinoma: a critical view of the evidence
- (2012) Augusto Villanueva et al. Nature Reviews Gastroenterology & Hepatology
- Heparin Inhibits Hepatocyte Growth Factor Induced Motility and Invasion of Hepatocellular Carcinoma Cells through Early Growth Response Protein 1
- (2012) Evin Ozen et al. PLoS One
- Global cancer statistics
- (2011) Ahmedin Jemal et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Activation of Phosphatidylinositol 3-Kinase/Akt Signaling Pathway Mediates Acquired Resistance to Sorafenib in Hepatocellular Carcinoma Cells
- (2011) K.-F. Chen et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Hepatocyte Growth Factor Expression in EGFR Mutant Lung Cancer with Intrinsic and Acquired Resistance to Tyrosine Kinase Inhibitors in a Japanese Cohort
- (2011) Seiji Yano et al. Journal of Thoracic Oncology
- Dovitinib Induces Apoptosis and Overcomes Sorafenib Resistance in Hepatocellular Carcinoma through SHP-1-Mediated Inhibition of STAT3
- (2011) W.-T. Tai et al. MOLECULAR CANCER THERAPEUTICS
- Hepatocyte growth factor (HGF) autocrine activation predicts sensitivity to MET inhibition in glioblastoma
- (2011) Q. Xie et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An overview of the c-MET signaling pathway
- (2011) Shawna Leslie Organ et al. Therapeutic Advances in Medical Oncology
- Preexistence and Clonal Selection of MET Amplification in EGFR Mutant NSCLC
- (2010) Alexa B. Turke et al. CANCER CELL
- HGF Rescues Colorectal Cancer Cells from EGFR Inhibition via MET Activation
- (2010) D. Liska et al. CLINICAL CANCER RESEARCH
- Targeting the HGF/Met signalling pathway in cancer
- (2010) Fabiola Cecchi et al. EUROPEAN JOURNAL OF CANCER
- MET signalling: principles and functions in development, organ regeneration and cancer
- (2010) Livio Trusolino et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer
- (2010) A Singh et al. ONCOGENE
- Differential expression of Caveolin-1 in hepatocellular carcinoma: correlation with differentiation state, motility and invasion
- (2009) Murat Cokakli et al. BMC CANCER
- Accelerated Metastasis after Short-Term Treatment with a Potent Inhibitor of Tumor Angiogenesis
- (2009) John M.L. Ebos et al. CANCER CELL
- Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis
- (2009) Marta Pàez-Ribes et al. CANCER CELL
- Canonical Wnt signaling is antagonized by noncanonical Wnt5a in hepatocellular carcinoma cells
- (2009) Haluk Yuzugullu et al. Molecular Cancer
- Systemic Therapy for Hepatocellular Carcinoma
- (2008) Melanie B. Thomas CANCER JOURNAL
- Met Receptor Contributes to Trastuzumab Resistance of Her2-Overexpressing Breast Cancer Cells
- (2008) D. L. Shattuck et al. CANCER RESEARCH
- Hepatocyte Growth Factor Induces Gefitinib Resistance of Lung Adenocarcinoma with Epidermal Growth Factor Receptor-Activating Mutations
- (2008) S. Yano et al. CANCER RESEARCH
- Hepatocarcinogenesis in mice with a conditional knockout of the hepatocyte growth factor receptor c-Met
- (2008) Philip Marx-Stoelting et al. INTERNATIONAL JOURNAL OF CANCER
- Sorafenib in Advanced Hepatocellular Carcinoma
- (2008) Josep M. Llovet et al. NEW ENGLAND JOURNAL OF MEDICINE
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