Phase I, multicenter, open-label, dose-escalation study of sonidegib in Asian patients with advanced solid tumors

SHH inhibitors for the treatment of medulloblastoma

(2015) Ayman Samkari et al.   Expert Review of Neurotherapeutics

Vismodegib in the treatment of basal cell carcinoma: indications for clinical practice

(2015) Piergiacomo Calzavara Pinton et al.   Future Oncology

Treatment with two different doses of sonidegib in patients with locally advanced or metastatic basal cell carcinoma (BOLT): a multicentre, randomised, double-blind phase 2 trial

(2015) Michael R Migden et al.   LANCET ONCOLOGY

SHH inhibitors for the treatment of medulloblastoma

(2015) Ayman Samkari et al.   Expert Review of Neurotherapeutics

Hedgehog Inhibitors in Rhabdomyosarcoma: A Comparison of Four Compounds and Responsiveness of Four Cell Lines

(2015) Rosalie Ridzewski et al.   Frontiers in Oncology

A Five-Gene Hedgehog Signature Developed as a Patient Preselection Tool for Hedgehog Inhibitor Therapy in Medulloblastoma

(2014) Yaping Shou et al.   CLINICAL CANCER RESEARCH

A Phase I, Multicenter, Open-Label, First-in-Human, Dose-Escalation Study of the Oral Smoothened Inhibitor Sonidegib (LDE225) in Patients with Advanced Solid Tumors

(2014) J. Rodon et al.   CLINICAL CANCER RESEARCH

Sonic hedgehog promotes autophagy of vascular smooth muscle cells

(2012) Haijie Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Hedgehog Partial Agonism Drives Warburg-like Metabolism in Muscle and Brown Fat

(2012) Raffaele Teperino et al.   CELL

Hedgehog signaling maintains hair follicle stem cell phenotype in young and aged human skin

(2009) Laure Rittié et al.   AGING CELL

New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1)

(2008) E.A. Eisenhauer et al.   EUROPEAN JOURNAL OF CANCER

Critical aspects of the Bayesian approach to phase I cancer trials

(2008) Beat Neuenschwander et al.   STATISTICS IN MEDICINE