Anti-repulsive Guidance Molecule C (RGMc) Antibodies Increases Serum Iron in Rats and Cynomolgus Monkeys by Hepcidin Downregulation

Title
Anti-repulsive Guidance Molecule C (RGMc) Antibodies Increases Serum Iron in Rats and Cynomolgus Monkeys by Hepcidin Downregulation
Authors
Keywords
ABT-207, h5F9-AM8, hepcidin, PK/PD analysis, safety assessment
Journal
AAPS Journal
Volume 17, Issue 4, Pages 930-938
Publisher
American Association of Pharmaceutical Scientists (AAPS)
Online
2015-04-21
DOI
10.1208/s12248-015-9770-4

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