Review
Oncology
Jinnan Xiao, Marques S. N. Ng, Tingting Yan, Ka Ming Chow, Carmen W. H. Chan
Summary: This review summarizes and synthesizes empirical literature on the experience of dignity in cancer patients, highlighting the importance of factors such as respect and self-worth in maintaining dignity. Factors associated with dignity include demographics, physical and psychosocial distress, experiences of suffering, and coping strategies.
Article
Biotechnology & Applied Microbiology
Tanja Kunej, Simon Horvat, Janez Salobir, Blaz Stres, Spela Mikec, Tomaz Accetto, Gorazd Avgustin, Bojana Bogovic Matijasic, Angela Cividini, Andreja Canzek Majhenic, Marko Cepon, Leon Deutsch, Ida Djurdjevic, Emil Erjavec, Gregor Gorjanc, Antonija Holcman, Dusanka Jordan, Luka Juvancic, Stane Kavcic, Ajda Kermauner, Marija Klopcic, Tina Kocjancic, Milena Kovac, Ales Kuhar, Andrej Lavrencic, Jakob Leskovec, Alenka Levart, Spela Malovrh, Romana Marinsek-Logar, Petra Mohar Lorbeg, Mojca Narat, Tanja Obermajer, Diana Paveljsek, Tatjana Pirman, Klemen Potocnik, Ilona Rac, Vida Rezar, Irena Rogelj, Mojca Simcic, Ales Snoj, Simona Susnik Bajec, Tanja Sumrada, Dusan Tercic, Primoz Treven, Masa Vodovnik, Manja Zupan Semrov, Jaka Zgajnar, Silvester Zgur, Peter Dovc
Summary: This article explores how integrative biology research in the 21st century can benefit from lessons learned in animal science. The authors share three key lessons from their experience in the past two decades, emphasizing the importance of cultivating multiomics knowledge through an integrative biology framework. They also highlight the significant prospects and relevance of studying animal science and nutrition in relation to human health, particularly during the current COVID-19 pandemic.
OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY
(2022)
Article
Oncology
Eran Ben-Arye, Naama Nijk, Ofer Lavie, Orit Gressel, Elad Schiff Md, Noah Samuels
Summary: This study examined the impact of a patient-tailored integrative oncology program on adherence to chemotherapy among patients with advanced gynecological cancer. The results showed that the patient-tailored program helped preserve adherence to chemotherapy, especially with taxane-based regimens.
SUPPORTIVE CARE IN CANCER
(2022)
Article
Biotechnology & Applied Microbiology
Dunja Manal Sabra, Anna Krin, Ana Belen Romeral, Johannes Ludwig Friess, Gunnar Jeremias
Summary: This study analyzes and assesses the potential bioterrorism threat arising from advances in synthetic biology, genome editing, and information availability. The results show that the affordability and ease of use of these technologies have led to an increase in the number and types of actors who could potentially weaponize B. anthracis. It highlights the importance of adapting biosecurity measures in political decision-making and the scientific community.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Pharmacology & Pharmacy
M. Berretta, S. Cazzavillan, M. Tinazzi, A. M. Peire, D. Santanga, A. Bignucolo, M. Montopoli
Summary: The purpose of this conference was to explain the relationship between integrative and complementary medicine and cancer through evidence-based medicine. The researchers used a multidisciplinary approach to improve the quality of life for cancer patients and highlight the risks of drugs and nutraceuticals.
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
(2022)
Article
Chemistry, Physical
Leonardo Vinicius Monteiro de Assis, Paulo Newton Tonolli, Maria Nathalia Moraes, Mauricio S. Baptista, Ana Maria de Lauro Castrucci
Summary: Human skin responses to sunlight involve both the beneficial and harmful effects of UV and visible light, which require a comprehensive understanding of the interactions of photons in the skin and the regulatory role of the light-sensing protein opsins.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY C-PHOTOCHEMISTRY REVIEWS
(2021)
Article
Biotechnology & Applied Microbiology
Elizabeth A. W. Sigston
Summary: The emergence of 3D printing is driving a major shift in translational medical research, introducing bidirectional translation and an entrepreneurial mindset. However, the rapid pace of development brings potential pitfalls and ethical concerns, requiring early recognition and management.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Review
Mathematics, Interdisciplinary Applications
Lourenco Corte Vieira, Rafael S. Costa, Duarte Valerio
Summary: Cancer, as a complex disease, has a significant impact on global mortality. Mathematical techniques, including fractional calculus, have been increasingly used in cancer modelling to study its intricate phenomena and improve understanding. This review provides an overview of the main trends and categories in cancer research, highlighting the growing application of fractional calculus in mathematical modelling. The review also outlines key research questions, challenges, and future perspectives.
FRACTAL AND FRACTIONAL
(2023)
Article
Neurosciences
Insoo Hyun, J. C. Scharf-Deering, Sarah Sullivan, John Dennis Aach, Paola Arlotta, Matthew L. Baum, George M. Church, Aaron Goldenberg, Henry T. Greely, Parastoo Khoshakhlagh, Richie E. Kohman, Melissa Lopes, Caroline Lowenthal, Aric Lu, Alex H. M. Ng, Sergiu P. Pasca, Bruna Paulsen, Martina Pigoni, Christopher T. Scott, David A. Silbersweig, Mark A. Skylar-Scott, Robert D. Truog, Jeantine E. Lunshof
Summary: By integrating ongoing bioethical collaboration, neuroscientists can have a positive impact on their research and the knowledge it generates. In this regard, the authors share their interdisciplinary model for promoting the ethical advancement of human neural organoid research.
NATURE NEUROSCIENCE
(2022)
Article
Oncology
Alexios-Fotios A. Mentis, Kostas A. Papavassiliou, Christina Piperi, Athanasios G. Papavassiliou
Summary: Cancer and brain research have historically focused on studying brain cancer, but now there is increasing interest in the field of neuro-oncology and the regulation of tumorigenesis in the nervous system. Evidence suggests that somatic mutations in cancer-related genes are also present in noncancerous brain disorders, indicating shared molecular alterations between cancer development/progression and nervous system pathologies. Understanding these commonalities could lead to repurposing cancer drugs for brain disorders and improving our understanding of the basis of these diseases.
INTERNATIONAL JOURNAL OF CANCER
(2023)
Review
Psychology
Jeff Miller, Rolf Ulrich
Summary: Recent evidence suggests that research practices in psychology and other disciplines are less effective than previously thought, leading to a crisis of confidence in psychological research. In response to this crisis, standard research practices have been scrutinized and various changes have been proposed to improve them. The field of metascience aims to use quantitative data gathering and modeling techniques to understand the reasons for inefficiency, assess the potential effects of suggested changes, and guide psychologists in conducting better science.
ANNUAL REVIEW OF PSYCHOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Nima Ghaderi, Joseph Jung, Sarah C. Brueningk, Ajay Subramanian, Lauren Nassour, Jeffrey Peacock
Summary: This review article discusses the application of radiotherapy and its current limitations, and proposes the use of mathematical simulations to identify optimal fractionation schedules.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Multidisciplinary Sciences
Sarah J. Stock, Catherine E. Aiken
Summary: Healthy pregnancies are crucial for populations, but there is a lack of therapies to improve pregnancy outcomes. The understanding of fundamental concepts like placentation and labor onset control is limited. The complex tripartite maternal-placental-fetal system poses challenges in studying pregnancy disorders, including the difficulty of creating relevant in vitro models and the uncertain applicability of animal models. Nevertheless, newer approaches such as trophoblast organoids and integrated data-science methods offer insights into healthy pregnancy physiology and potential therapeutic targets.
Review
Immunology
Elisa Cappuzzello, Emilia Vigolo, Giulia D'Accardio, Giuseppe Astori, Antonio Rosato, Roberta Sommaggio
Summary: The successful treatment of B-cell malignancies with CAR-T cells was a breakthrough, but not all patients can benefit from this therapy. CIK cells, as an alternative cellular therapy, have the potential to overcome some of the limitations of CAR-T cells.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Developmental Biology
Scott F. Gilbert, Michael G. Hadfield
Summary: This article discusses the contribution of developmental biology to mitigating the consequences of human impacts on the environment and climate change. It emphasizes the need for developmental biology to consider the environment as part of the body and to explore the interactions between developing organisms and their chemical, physical, and biotic environments.
