Identification of Platform-Independent Diagnostic Biomarker Panel for Hepatocellular Carcinoma Using Large-Scale Transcriptomics Data

Cancer statistics, 2019

(2019) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

High expression B3GAT3 is related with poor prognosis of liver cancer

(2019) Yan-li Zhang et al.   Open Medicine

Clinical characteristics and prognosis of 2887 patients with hepatocellular carcinoma

(2019) Chun-yan Wang et al.   MEDICINE

In Silico Analysis of Gene Expression Change Associated with Copy Number of Enhancers in Pancreatic Adenocarcinoma

(2019) Rajesh Kumar et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Classification of early and late stage liver hepatocellular carcinoma patients from their genomics and epigenomics profiles

(2019) Harpreet Kaur et al.   PLoS One

Prediction and Analysis of Skin Cancer Progression using Genomics Profiles of Patients

(2019) Sherry Bhalla et al.   Scientific Reports

Fatty Acid Binding Protein 4 (FABP4) Overexpression in Intratumoral Hepatic Stellate Cells within Hepatocellular Carcinoma with Metabolic Risk Factors

(2018) Norimichi Chiyonobu et al.   AMERICAN JOURNAL OF PATHOLOGY

Screening for immune-potentiating antigens from hepatocellular carcinoma patients after radiofrequency ablation by serum proteomic analysis

(2018) Shunli Shen et al.   BMC CANCER

An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics

(2018) Jianfang Liu et al.   CELL

A six-gene-based prognostic signature for hepatocellular carcinoma overall survival prediction

(2018) Zhenglu Wang et al.   LIFE SCIENCES

Molecular Signature and Mechanisms of Hepatitis D Virus-Associated Hepatocellular Carcinoma

(2018) Giacomo Diaz et al.   MOLECULAR CANCER RESEARCH

Construction of a set of novel and robust gene expression signatures predicting prostate cancer recurrence

(2018) Yanzhi Jiang et al.   Molecular Oncology

The Identification of Core Gene Expression Signature in Hepatocellular Carcinoma

(2018) Ning Li et al.   Oxidative Medicine and Cellular Longevity

Personalized disease signatures through information-theoretic compaction of big cancer data

(2018) Swetha Vasudevan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CLEC1B Expression and PD-L1 Expression Predict Clinical Outcome in Hepatocellular Carcinoma with Tumor Hemorrhage

(2018) Kuan Hu et al.   Translational Oncology

Reducing protein regulator of cytokinesis 1 as a prospective therapy for hepatocellular carcinoma

(2018) Xinran Liu et al.   Cell Death & Disease

Cancer epigenetics: Moving forward

(2018) Angela Nebbioso et al.   PLoS Genetics

Infection with hepatitis C virus depends on TACSTD2, a regulator of claudin-1 and occludin highly downregulated in hepatocellular carcinoma

(2018) Vandana Sekhar et al.   PLoS Pathogens

Distinct Diagnostic and Prognostic Values of Minichromosome Maintenance Gene Expression in Patients with Hepatocellular Carcinoma

(2018) Xiwen Liao et al.   Journal of Cancer

Gene Expression Detection Assay for Cancer Clinical Use

(2018) Shavira Narrandes et al.   Journal of Cancer

Direct comparison of five serum biomarkers in early diagnosis of hepatocellular carcinoma

(2018) Hongda Chen et al.   Cancer Management and Research

Identification and Validation of a Diagnostic and Prognostic Multi-Gene Biomarker Panel for Pancreatic Ductal Adenocarcinoma

(2018) Hagen Klett et al.   Frontiers in Genetics

Identification of novel biomarkers for hepatocellular carcinoma using transcriptome analysis

(2018) Qianlin Xia et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Identification of biomarkers for Barcelona Clinic Liver Cancer staging and overall survival of patients with hepatocellular carcinoma

(2018) Wei Xu et al.   PLoS One

Polycomb complexes associate with enhancers and promote oncogenic transcriptional programs in cancer through multiple mechanisms

(2018) Ho Lam Chan et al.   Nature Communications

A miRNA Combination as Promising Biomarker for Hepatocellular Carcinoma Diagnosis: A Study Based on Bioinformatics Analysis

(2018) Jia Ji et al.   Journal of Cancer

GALAD Score for Hepatocellular Carcinoma Detection in Comparison to Liver Ultrasound and Proposal of GALADUS Score

(2018) Ju Dong Yang et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Using microarray-based subtyping methods for breast cancer in the era of high-throughput RNA sequencing

(2018) Christina Bligaard Pedersen et al.   Molecular Oncology

Comparative efficacy of treatment strategies for hepatocellular carcinoma: systematic review and network meta-analysis

(2018) Guo Tian et al.   BMJ Open

Ficolin-1 and Ficolin-3 Plasma Levels Are Altered in HIV and HIV/HCV Coinfected Patients From Southern Brazil

(2018) Maria Regina Tizzot et al.   Frontiers in Immunology

Large-scale analysis reveals a novel risk score to predict overall survival in hepatocellular carcinoma

(2018) Yujia Zheng et al.   Cancer Management and Research

Importance of tumor size at diagnosis as a prognostic factor for hepatocellular carcinoma survival: a population-based study

(2018) Guoyi Wu et al.   Cancer Management and Research

SUMOylation regulates LKB1 localization and its oncogenic activity in liver cancer

(2018) Imanol Zubiete-Franco et al.   EBioMedicine

The identification of key genes and pathways in hepatocellular carcinoma by bioinformatics analysis of high-throughput data

(2017) Chaoyang Zhang et al.   MEDICAL ONCOLOGY

STAT3-mediated upregulation of lncRNA HOXD-AS1 as a ceRNA facilitates liver cancer metastasis by regulating SOX4

(2017) Hui Wang et al.   Molecular Cancer

Tumor-adjacent tissue co-expression profile analysis reveals pro-oncogenic ribosomal gene signature for prognosis of resectable hepatocellular carcinoma

(2017) Oleg V. Grinchuk et al.   Molecular Oncology

Epigenetic plasticity and the hallmarks of cancer

(2017) William A. Flavahan et al.   SCIENCE

Epigenetic drivers of tumourigenesis and cancer metastasis

(2017) Aniruddha Chatterjee et al.   SEMINARS IN CANCER BIOLOGY

Integrative analysis of genomic and epigenomic regulation of the transcriptome in liver cancer

(2017) Hyun Goo Woo et al.   Nature Communications

Circulating miRNAs as novel diagnostic biomarkers in hepatocellular carcinoma detection: a meta-analysis based on 24 articles

(2017) Yan Ding et al.   Oncotarget

Gene expression-based biomarkers for discriminating early and late stage of clear cell renal cancer

(2017) Sherry Bhalla et al.   Scientific Reports

Exploitation of Gene Expression and Cancer Biomarkers in Paving the Path to Era of Personalized Medicine

(2017) Hala Fawzy Mohamed Kamel et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Prognostic Biomarker Identification Through Integrating the Gene Signatures of Hepatocellular Carcinoma Properties

(2017) Jialin Cai et al.   EBioMedicine

Alpha-foetoprotein (AFP): A multi-purpose marker in hepatocellular carcinoma

(2016) Chloé Sauzay et al.   CLINICA CHIMICA ACTA

The microtubule-associated protein PRC1 promotes early recurrence of hepatocellular carcinoma in association with the Wnt/β-catenin signalling pathway

(2016) Jianxiang Chen et al.   GUT

Toward a Shared Vision for Cancer Genomic Data

(2016) Robert L. Grossman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Enrichr: a comprehensive gene set enrichment analysis web server 2016 update

(2016) Maxim V. Kuleshov et al.   NUCLEIC ACIDS RESEARCH

Diagnostic Evaluation of Des-Gamma-Carboxy Prothrombin versus α-Fetoprotein for Hepatitis B Virus-Related Hepatocellular Carcinoma in China: A Large-Scale, Multicentre Study

(2016) Jun Ji et al.   PLoS One

The GALAD scoring algorithm based on AFP, AFP-L3, and DCP significantly improves detection of BCLC early stage hepatocellular carcinoma

(2016) J. Best et al.   ZEITSCHRIFT FUR GASTROENTEROLOGIE

NUPR1, a new target in liver cancer: implication in controlling cell growth, migration, invasion and sorafenib resistance

(2016) M R Emma et al.   Cell Death & Disease

Integrin α2β1 inhibits MST1 kinase phosphorylation and activates Yes-associated protein oncogenic signaling in hepatocellular carcinoma

(2016) Kwong-Fai Wong et al.   Oncotarget

Molecular Pathogenesis of Hepatocellular Carcinoma

(2016) Daniel Wai-Hung Ho et al.   Liver Cancer

Genome-wide identification of RNA editing in hepatocellular carcinoma

(2015) Lin Kang et al.   GENOMICS

Neoangiogenesis-related genes are hallmarks of fast-growing hepatocellular carcinomas and worst survival. Results from a prospective study

(2015) Erica Villa et al.   GUT

Low serum ficolin-3 levels are associated with severity and poor outcome in traumatic brain injury

(2015) Jian-Wei Pan et al.   Journal of Neuroinflammation

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Integrative genomics identifies YY1AP1 as an oncogenic driver in EpCAM+ AFP+ hepatocellular carcinoma

(2015) X Zhao et al.   ONCOGENE

Identification of Hepatocellular Carcinoma-associated Hub Genes and Pathways by Integrated Microarray Analysis

(2015) Fangfeng Liu et al.   TUMORI

Comprehensive analysis of transcriptome and metabolome analysis in Intrahepatic Cholangiocarcinoma and Hepatocellular Carcinoma

(2015) Yoshiki Murakami et al.   Scientific Reports

Machine learning applications in cancer prognosis and prediction

(2015) Konstantina Kourou et al.   Computational and Structural Biotechnology Journal

Identification of Hepatocellular Carcinoma-associated Hub Genes and Pathways by Integrated Microarray Analysis

(2015) Fangfeng Liu et al.   TUMORI JOURNAL

Identification of HBV-MLL4 Integration and Its Molecular Basis in Chinese Hepatocellular Carcinoma

(2015) Hua Dong et al.   PLoS One

Big Data and Large Sample Size: A Cautionary Note on the Potential for Bias

(2014) Robert M. Kaplan et al.   CTS-Clinical and Translational Science

Gene: a gene-centered information resource at NCBI

(2014) Garth R. Brown et al.   NUCLEIC ACIDS RESEARCH

Methylation Profiles Reveal Distinct Subgroup of Hepatocellular Carcinoma Patients with Poor Prognosis

(2014) Way-Champ Mah et al.   PLoS One

PCMdb: Pancreatic Cancer Methylation Database

(2014) Gandharva Nagpal et al.   Scientific Reports

Genomic Predictors for Recurrence Patterns of Hepatocellular Carcinoma: Model Derivation and Validation

(2014) Ji Hoon Kim et al.   PLOS MEDICINE

Prediction of Disease-free Survival in Hepatocellular Carcinoma by Gene Expression Profiling

(2013) Ho-Yeong Lim et al.   ANNALS OF SURGICAL ONCOLOGY

Global Gene Expression Profiling Reveals SPINK1 as a Potential Hepatocellular Carcinoma Marker

(2013) Aileen Marshall et al.   PLoS One

A Machine Learned Classifier That Uses Gene Expression Data to Accurately Predict Estrogen Receptor Status

(2013) Meysam Bastani et al.   PLoS One

Cancer Epigenetics: From Mechanism to Therapy

(2012) Mark A. Dawson et al.   CELL

Transcriptomic profiling reveals hepatic stem-like gene signatures and interplay of miR-200c and epithelial-mesenchymal transition in intrahepatic cholangiocarcinoma

(2012) Naoki Oishi et al.   HEPATOLOGY

A fibrous stromal component in hepatocellular carcinoma reveals a cholangiocarcinoma-like gene expression trait and epithelial-mesenchymal transition

(2012) Jae Yeon Seok et al.   HEPATOLOGY

NCBI GEO: archive for functional genomics data sets—update

(2012) Tanya Barrett et al.   NUCLEIC ACIDS RESEARCH

Gene Expression Profiles for Predicting Metastasis in Breast Cancer: A Cross-Study Comparison of Classification Methods

(2012) Mark Burton et al.   TheScientificWorldJOURNAL

Definition of the Landscape of Promoter DNA Hypomethylation in Liver Cancer

(2011) B. Stefanska et al.   CANCER RESEARCH

Clinicopathological and prognostic significance of serum and tissue Dickkopf-1 levels in human hepatocellular carcinoma

(2011) Edmund Kwok-Kwan Tung et al.   LIVER INTERNATIONAL

Predictive Genes in Adjacent Normal Tissue Are Preferentially Altered by sCNV during Tumorigenesis in Liver Cancer and May Rate Limiting

(2011) John R. Lamb et al.   PLoS One

A framework for oligonucleotide microarray preprocessing

(2010) Benilton S. Carvalho et al.   BIOINFORMATICS

A Unique Metastasis Gene Signature Enables Prediction of Tumor Relapse in Early-Stage Hepatocellular Carcinoma Patients

(2010) S. Roessler et al.   CANCER RESEARCH

Identification of genes preferentially methylated in hepatitis C virus-related hepatocellular carcinoma

(2010) Ying-Bing Deng et al.   CANCER SCIENCE

Epigenetics in cancer

(2009) S. Sharma et al.   CARCINOGENESIS

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(2009) Valeria Mas et al.   MOLECULAR MEDICINE

lumi: a pipeline for processing Illumina microarray

(2008) P. Du et al.   BIOINFORMATICS