Comprehensive draft of the mouse embryonic fibroblast lysosomal proteome by mass spectrometry based proteomics

Combining LOPIT with differential ultracentrifugation for high-resolution spatial proteomics

(2019) Aikaterini Geladaki et al.   Nature Communications

NUFIP1 is a ribosome receptor for starvation-induced ribophagy

(2018) Gregory A. Wyant et al.   SCIENCE

Targeted analysis of lysosomal directed proteins and their sites of mannose-6-phosphate modification

(2018) Tomislav Caval et al.   MOLECULAR & CELLULAR PROTEOMICS

Systematic Evaluation of Protein Reduction and Alkylation Reveals Massive Unspecific Side Effects by Iodine-containing Reagents

(2017) Torsten Müller et al.   MOLECULAR & CELLULAR PROTEOMICS

Statistical control of peptide and protein error rates in large-scale targeted data-independent acquisition analyses

(2017) George Rosenberger et al.   NATURE METHODS

Using hyperLOPIT to perform high-resolution mapping of the spatial proteome

(2017) Claire M Mulvey et al.   Nature Protocols

Lysosomal metabolomics reveals V-ATPase- and mTOR-dependent regulation of amino acid efflux from lysosomes

(2017) Monther Abu-Remaileh et al.   SCIENCE

A novel approach to analyze lysosomal dysfunctions through subcellular proteomics and lipidomics: the case of NPC1 deficiency

(2017) Arun Kumar Tharkeshwar et al.   Scientific Reports

Brain Disorders Due to Lysosomal Dysfunction

(2016) Alessandro Fraldi et al.   Annual Review of Neuroscience

The awesome lysosome

(2016) A. Ballabio   EMBO Molecular Medicine

The lysosome as a command-and-control center for cellular metabolism

(2016) Chun-Yan Lim et al.   JOURNAL OF CELL BIOLOGY

High-precision iRT prediction in the targeted analysis of data-independent acquisition and its impact on identification and quantitation

(2016) Roland Bruderer et al.   PROTEOMICS

Global, quantitative and dynamic mapping of protein subcellular localization

(2016) Daniel N Itzhak et al.   eLife

Extending the Mannose 6-Phosphate Glycoproteome by High Resolution/Accuracy Mass Spectrometry Analysis of Control and Acid Phosphatase 5-Deficient Mice

(2013) David E. Sleat et al.   MOLECULAR & CELLULAR PROTEOMICS

An Extended Proteome Map of the Lysosomal Membrane Reveals Novel Potential Transporters

(2013) Agnès Chapel et al.   MOLECULAR & CELLULAR PROTEOMICS

Protein carbamylation: In vivo modification or in vitro artefact?

(2013) Laxmikanth Kollipara et al.   PROTEOMICS

Proteomic analysis of mouse models of Niemann-Pick C disease reveals alterations in the steady-state levels of lysosomal proteins within the brain

(2012) David E. Sleat et al.   PROTEOMICS

Proteomic Identification of Protease Cleavage Sites Characterizes Prime and Non-prime Specificity of Cysteine Cathepsins B, L, and S

(2011) Martin L. Biniossek et al.   JOURNAL OF PROTEOME RESEARCH

Mannose 6 Dephosphorylation of Lysosomal Proteins Mediated by Acid Phosphatases Acp2 and Acp5

(2011) G. Makrypidi et al.   MOLECULAR AND CELLULAR BIOLOGY

Optimization of cell lysis and protein digestion protocols for the analysis of HeLa S3 cells by LC-MS/MS

(2011) Dominic Winter et al.   PROTEOMICS

mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H+-ATPase

(2011) R. Zoncu et al.   SCIENCE

Mass Spectrometry-based Protein Profiling to Determine the Cause of Lysosomal Storage Diseases of Unknown Etiology

(2009) David E. Sleat et al.   MOLECULAR & CELLULAR PROTEOMICS

Universal sample preparation method for proteome analysis

(2009) Jacek R Wiśniewski et al.   NATURE METHODS

Proteomics of the lysosome

(2008) Torben Lübke et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Lysosomal disorders: From storage to cellular damage

(2008) Andrea Ballabio et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The Mannose 6-Phosphate Glycoprotein Proteome

(2008) David E. Sleat et al.   JOURNAL OF PROTEOME RESEARCH