Systemic β-Adrenergic Receptor Activation Augments the ex vivo Expansion and Anti-Tumor Activity of Vγ9Vδ2 T-Cells

γδ cell-based immunotherapy for cancer

(2019) Elena Lo Presti et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

A single exercise bout augments adenovirus-specific T-cell mobilization and function

(2018) Hawley E. Kunz et al.   PHYSIOLOGY & BEHAVIOR

Lymphocytes and monocytes egress peripheral blood within minutes after cessation of steady state exercise: A detailed temporal analysis of leukocyte extravasation

(2018) Bridgette V. Rooney et al.   PHYSIOLOGY & BEHAVIOR

Improving the Efficiency of Vγ9Vδ2 T-Cell Immunotherapy in Cancer

(2018) Timm Hoeres et al.   Frontiers in Immunology

Debunking the Myth of Exercise-Induced Immune Suppression: Redefining the Impact of Exercise on Immunological Health Across the Lifespan

(2018) John P. Campbell et al.   Frontiers in Immunology

Gamma Delta T Cell Therapy for Cancer: It Is Good to be Local

(2018) C. David Pauza et al.   Frontiers in Immunology

β2-Adrenergic receptor signaling mediates the preferential mobilization of differentiated subsets of CD8+ T-cells, NK-cells and non-classical monocytes in response to acute exercise in humans

(2018) Rachel M. Graff et al.   BRAIN BEHAVIOR AND IMMUNITY

NK-cell function is impaired during long-duration spaceflight

(2018) Austin B. Bigley et al.   JOURNAL OF APPLIED PHYSIOLOGY

Mobilizing Immune Cells With Exercise for Cancer Immunotherapy

(2017) Richard J. Simpson et al.   EXERCISE AND SPORT SCIENCES REVIEWS

Key Features of Gamma-Delta T-Cell Subsets in Human Diseases and Their Immunotherapeutic Implications

(2017) Myriam Lawand et al.   Frontiers in Immunology

Zoledronic acid boosts γδ T-cell activity in children receiving αβ+ T and CD19+ cell-depleted grafts from an HLA-haplo-identical donor

(2017) A. Bertaina et al.   OncoImmunology

A systems biology approach to investigating the influence of exercise and fitness on the composition of leukocytes in peripheral blood

(2017) Michael P. Gustafson et al.   Journal for ImmunoTherapy of Cancer

A promising sword of tomorrow: Human γδ T cell strategies reconcile allo-HSCT complications

(2016) Yongxian Hu et al.   BLOOD REVIEWS

In vivo expansion and activation of γδ T cells as immunotherapy for refractory neuroblastoma

(2016) Joseph G. Pressey et al.   MEDICINE

A single exercise bout enhances the manufacture of viral-specific T-cells from healthy donors: implications for allogeneic adoptive transfer immunotherapy

(2016) Guillaume Spielmann et al.   Scientific Reports

Gamma Delta T Cell Reconstitution Is Associated with Fewer Infections and Improved Event-Free Survival after Hematopoietic Stem Cell Transplantation for Pediatric Leukemia

(2015) Ross Perko et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

   T-cell reconstitution after HLA-haploidentical hematopoietic transplantation depleted of TCR-  +/CD19+ lymphocytes

(2015) I. Airoldi et al.   BLOOD

A single bout of dynamic exercise by healthy adults enhances the generation of monocyte-derived-dendritic cells

(2015) Emily C.P. LaVoy et al.   CELLULAR IMMUNOLOGY

Direct and Indirect Effects of Cytomegalovirus-Induced γδ T Cells after Kidney Transplantation

(2015) Lionel Couzi et al.   Frontiers in Immunology

Ex vivoexpanded human circulating Vδ1 γδT cells exhibit favorable therapeutic potential for colon cancer

(2015) Dang Wu et al.   OncoImmunology

Transmissible cytotoxicity of multiple myeloma cells by cord blood-derived NK cells is mediated by vesicle trafficking

(2014) B Martin-Antonio et al.   CELL DEATH AND DIFFERENTIATION

Successful adoptive transfer and in vivo expansion of haploidentical γδ T cells

(2014) Martin Wilhelm et al.   Journal of Translational Medicine

Plasticity of γδ T Cells: Impact on the Anti-Tumor Response

(2014) Virginie Lafont et al.   Frontiers in Immunology

Acute exercise preferentially redeploys NK-cells with a highly-differentiated phenotype and augments cytotoxicity against lymphoma and multiple myeloma target cells

(2013) Austin B. Bigley et al.   BRAIN BEHAVIOR AND IMMUNITY

The effects of age and viral serology on γδ T-cell numbers and exercise responsiveness in humans

(2013) Mira Pistillo et al.   CELLULAR IMMUNOLOGY

NKG2D regulates production of soluble TRAIL by ex vivo expanded human γδ T cells

(2013) Pouneh Dokouhaki et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Current and future approaches to treat graft failure after allogeneic hematopoietic stem cell transplantation

(2013) Franco Locatelli et al.   EXPERT OPINION ON PHARMACOTHERAPY

Essential Requirements of Zoledronate-Induced Cytokine and    T Cell Proliferative Responses

(2013) O. Nussbaumer et al.   JOURNAL OF IMMUNOLOGY

CMV-Independent Lysis of Glioblastoma by Ex Vivo Expanded/Activated Vδ1+ γδ T Cells

(2013) Andrea Knight et al.   PLoS One

Human Vδ2 versus non-Vδ2 γδ T cells in antitumor immunity

(2013) Dieter Kabelitz et al.   OncoImmunology

Human Vdelta1 gamma-delta T cells exert potent specific cytotoxicity against primary multiple myeloma cells

(2012) Andrea Knight et al.   CYTOTHERAPY

Human Vδ1 γδ T cells expanded from peripheral blood exhibit specific cytotoxicity against B-cell chronic lymphocytic leukemia-derived cells

(2011) Gabrielle M. Siegers et al.   CYTOTHERAPY

Expansion of Human Peripheral Blood γδ T Cells using Zoledronate

(2011) Makoto Kondo et al.   Jove-Journal of Visualized Experiments

Phenotypic characterization of γδ T cells mobilized in response to acute psychological stress

(2010) Leila H. Anane et al.   BRAIN BEHAVIOR AND IMMUNITY

Mobilization of γδ T lymphocytes in response to psychological stress, exercise, and β-agonist infusion

(2009) Leila H. Anane et al.   BRAIN BEHAVIOR AND IMMUNITY

Acute exercise mobilises CD8+ T lymphocytes exhibiting an effector-memory phenotype

(2009) John P. Campbell et al.   BRAIN BEHAVIOR AND IMMUNITY

Large scale expansion of Vγ9Vδ2 T lymphocytes from human peripheral blood mononuclear cells after a positive selection using MACS “TCR γ/δ + T cell isolation kit”

(2009) Samuel Salot et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Peripheral blood monocytes are responsible for γδ T cell activation induced by zoledronic acid through accumulation of IPP/DMAPP

(2008) Anke J. Roelofs et al.   BRITISH JOURNAL OF HAEMATOLOGY

Zoledronate facilitates large-scale ex vivo expansion of functional γδ T cells from cancer patients for use in adoptive immunotherapy*

(2008) M. Kondo et al.   CYTOTHERAPY