FA-97, a New Synthetic Caffeic Acid Phenethyl Ester Derivative, Ameliorates DSS-Induced Colitis Against Oxidative Stress by Activating Nrf2/HO-1 Pathway

Cytokine Networks in the Pathophysiology of Inflammatory Bowel Disease

(2019) Matthias Friedrich et al.   IMMUNITY

Mitophagy Reduces Oxidative Stress Via Keap1 (Kelch-Like Epichlorohydrin-Associated Protein 1)/Nrf2 (Nuclear Factor-E2-Related Factor 2)/PHB2 (Prohibitin 2) Pathway After Subarachnoid Hemorrhage in Rats

(2019) Tongyu Zhang et al.   STROKE

Targeting immune cell circuits and trafficking in inflammatory bowel disease

(2019) Markus F. Neurath   NATURE IMMUNOLOGY

Assessment of the Antigenotoxic Activity of Poly(d,l-lactic-co-glycolic acid) Nanoparticles Loaded with Caffeic Acid Phenethyl Ester Using the Ames Salmonella/Microsome Assay

(2018) Tülin Arasoğlu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Transcription Factor NRF2 as a Therapeutic Target for Chronic Diseases: A Systems Medicine Approach

(2018) Antonio Cuadrado et al.   PHARMACOLOGICAL REVIEWS

Inflammasome, Inflammation, and Tissue Homeostasis

(2018) Vijay A.K. Rathinam et al.   TRENDS IN MOLECULAR MEDICINE

Prdx6 Deficiency Ameliorates DSS Colitis: Relevance of Compensatory Antioxidant Mechanisms

(2017) Hassan Melhem et al.   Journal of Crohns & Colitis

Worldwide incidence and prevalence of inflammatory bowel disease in the 21st century: a systematic review of population-based studies

(2017) Siew C Ng et al.   LANCET

Caffeic acid phenethyl ester is protective in experimental ulcerative colitis via reduction in levels of pro-inflammatory mediators and enhancement of epithelial barrier function

(2017) Mohammed N. Khan et al.   INFLAMMOPHARMACOLOGY

Small Molecule Inhibitor of NRF2 Selectively Intervenes Therapeutic Resistance in KEAP1-Deficient NSCLC Tumors

(2016) Anju Singh et al.   ACS Chemical Biology

Overexpression of HDAC6 induces pro-inflammatory responses by regulating ROS-MAPK-NF-κB/AP-1 signaling pathways in macrophages

(2016) Gi Soo Youn et al.   FREE RADICAL BIOLOGY AND MEDICINE

Drug development in IBD: from novel target identification to early clinical trials

(2016) Silvio Danese et al.   GUT

Emerging Roles for Noncanonical NF-κB Signaling in the Modulation of Inflammatory Bowel Disease Pathobiology

(2016) Dylan K. McDaniel et al.   INFLAMMATORY BOWEL DISEASES

TNF-α modulates genome-wide redistribution of ΔNp63α/TAp73 and NF-κB cREL interactive binding on TP53 and AP-1 motifs to promote an oncogenic gene program in squamous cancer

(2016) H Si et al.   ONCOGENE

Mechanisms behind efficacy of tumor necrosis factor inhibitors in inflammatory bowel diseases

(2016) Caroline Meyer Olesen et al.   PHARMACOLOGY & THERAPEUTICS

Molecular Characterization and Enhancement of Anticancer Activity of Caffeic Acid Phenethyl Ester by γ Cyclodextrin

(2016) Renu Wadhwa et al.   Journal of Cancer

Gallic acid attenuates dextran sulfate sodium-induced experimental colitis in BALB/c mice

(2015) Ashok Kumar Pandurangan et al.   Drug Design Development and Therapy

Endoscopic ultrasound of the colon for the differentiation of Crohn's disease and ulcerative colitis in comparison with healthy controls

(2014) M. Ellrichmann et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Caffeic Acid Phenethyl Ester: A Review of Its Antioxidant Activity, Protective Effects against Ischemia-reperfusion Injury and Drug Adverse Reactions

(2014) Mai F. Tolba et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Wogonin prevents lipopolysaccharide-induced acute lung injury and inflammation in mice via peroxisome proliferator-activated receptor gamma-mediated attenuation of the nuclear factor-kappaB pathway

(2014) Jing Yao et al.   IMMUNOLOGY

Role of Nrf2 in Oxidative Stress and Toxicity

(2013) Qiang Ma   Annual Review of Pharmacology and Toxicology

Development and validation of an LCMS method to determine the pharmacokinetic profiles of caffeic acid phenethyl amide and caffeic acid phenethyl ester in male Sprague-Dawley rats

(2013) John Yang et al.   BIOMEDICAL CHROMATOGRAPHY

DSS-induced acute colitis in C57BL/6 mice is mitigated by sulforaphane pre-treatment

(2013) Anika E. Wagner et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Toward clinical application of the Keap1–Nrf2 pathway

(2013) Takafumi Suzuki et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

CD11b + Bone Marrow–Derived Monocytes Are the Major Leukocyte Subset Responsible for Retinal Capillary Leukostasis in Experimental Diabetes in Mouse and Express High Levels of CCR5 in the Circulation

(2012) Andreia M. Serra et al.   AMERICAN JOURNAL OF PATHOLOGY

Oxidative stress and redox signaling mechanisms of inflammatory bowel disease: updated experimental and clinical evidence

(2012) Hong Zhu et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Small Molecule Modulators of Keap1-Nrf2-ARE Pathway as Potential Preventive and Therapeutic Agents

(2012) Sadagopan Magesh et al.   MEDICINAL RESEARCH REVIEWS

Epithelial Barriers in Intestinal Inflammation

(2011) Lena J. John et al.   ANTIOXIDANTS & REDOX SIGNALING

The cytoprotective role of the Keap1–Nrf2 pathway

(2011) Liam Baird et al.   ARCHIVES OF TOXICOLOGY

New therapies for inflammatory bowel disease: from the bench to the bedside

(2011) Silvio Danese   GUT

Involvement of oxidative stress and mucosal addressin cell adhesion molecule-1 (MAdCAM-1) in inflammatory bowel disease

(2011) Satoshi Tanida et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Genetics and pathogenesis of inflammatory bowel disease

(2011) Bernard Khor et al.   NATURE

Inflammatory Bowel Disease

(2010) Arthur Kaser et al.   Annual Review of Immunology

Oxidative state and IL-6 production in intestinal myofibroblasts of Crohnʼs disease patients

(2010) Serena Catarzi et al.   INFLAMMATORY BOWEL DISEASES

Protein profiles of peripheral blood mononuclear cells are useful for differential diagnosis of ulcerative colitis and Crohn’s disease

(2010) Moriaki Hatsugai et al.   JOURNAL OF GASTROENTEROLOGY

New pathophysiological insights and modern treatment of IBD

(2010) Matthias A. Engel et al.   JOURNAL OF GASTROENTEROLOGY

Increased Susceptibility of Nrf2 Knockout Mice to Colitis-Associated Colorectal Cancer

(2008) T. O. Khor et al.   Cancer Prevention Research

Therapeutic potency of IL2-caspase 3 targeted treatment in a murine experimental model of inflammatory bowel disease

(2008) S Shteingart et al.   GUT

Oxidative stress in ulcerative colitis-associated carcinogenesis

(2008) A. Roessner et al.   PATHOLOGY RESEARCH AND PRACTICE