Long-Term Ibrutinib Therapy Reverses CD8+ T Cell Exhaustion in B Cell Chronic Lymphocytic Leukaemia
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Title
Long-Term Ibrutinib Therapy Reverses CD8+ T Cell Exhaustion in B Cell Chronic Lymphocytic Leukaemia
Authors
Keywords
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Journal
Frontiers in Immunology
Volume 10, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2019-12-12
DOI
10.3389/fimmu.2019.02832
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- Ibrutinib enhances chimeric antigen receptor T-cell engraftment and efficacy in leukemia
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- Disruption of in vivo Chronic Lymphocytic Leukemia Tumor-Microenvironment Interactions by Ibrutinib - Findings from an Investigator-Initiated Phase II Study
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- Acyclovir Therapy Reduces the CD4+ T Cell Response against the Immunodominant pp65 Protein from Cytomegalovirus in Immune Competent Individuals
- (2015) Annette Pachnio et al. PLoS One
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- (2013) J. A. Dubovsky et al. BLOOD
- CMV-specific CD8+ T-cell function is not impaired in chronic lymphocytic leukemia
- (2013) G. D. te Raa et al. BLOOD
- Targeting BTK with Ibrutinib in Relapsed Chronic Lymphocytic Leukemia
- (2013) John C. Byrd et al. NEW ENGLAND JOURNAL OF MEDICINE
- Seropositivity for CMV and IL-6 levels are associated with grip strength and muscle size in the elderly
- (2013) Alixe HM Kilgour et al. Immunity & Ageing
- T cells from CLL patients exhibit features of T-cell exhaustion but retain capacity for cytokine production
- (2012) J. C. Riches et al. BLOOD
- Expansion of a CD8+PD-1+ Replicative Senescence Phenotype in Early Stage CLL Patients Is Associated with Inverted CD4:CD8 Ratios and Disease Progression
- (2011) C. Nunes et al. CLINICAL CANCER RESEARCH
- T cell exhaustion
- (2011) E John Wherry NATURE IMMUNOLOGY
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