4.5 Article

Flies from a tertiary hospital in Rwanda carry multidrug-resistant Gram-negative pathogens including extended-spectrum beta-lactamase-producing E. coli sequence type 131

Journal

Publisher

BMC
DOI: 10.1186/s13756-020-0696-y

Keywords

MRGN; Vector flies; Virulence

Funding

  1. German Federal Ministry for Economic Cooperation and Development via the ESTHER programme (Ensemble pour une Solidarite Therapeutique Hospitaliere En Reseau)
  2. DFG (German Research Foundation) [393148499]
  3. Open Access Publication Fund of the University of Greifswald

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Multidrug-resistant gram-negative (MRGN) bacteria are a serious threat to global health. We used genomics to study MRGN obtained from houseflies in a tertiary Rwandan hospital. Our analysis revealed a high abundance of different MRGN including E. coli pathogenic lineage ST131 suggesting the important role of flies in disseminating highly virulent pathogens in clinical settings and beyond.

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