Article
Entomology
Yi Yan, Hong Yang, Kang-kang Xu, Da-Ming Hu, Wen-jia Yang
Summary: The study identified i-type and c-type lysozymes in the cigarette beetle, Lasioderma serricorne, which are highly expressed in late larvae and pupae and induced by 20-hydroxyecdysone. Knockdown of LsLysI and/or LsLysC reduced lysozyme levels and disrupted larval-to-pupa molt, leading to increased larval mortality after Staphylococcus aureus infection. The results suggest that LsLysI and LsLysC play key roles in immune response and developmental processes of L. serricorne.
JOURNAL OF STORED PRODUCTS RESEARCH
(2021)
Article
Biochemistry & Molecular Biology
Yi Yan, Ming-Huan Jia, Zhi-Jun Le, Kang-Kang Xu, Can Li, Wen-Jia Yang
Summary: The four LsPGRP genes play important and distinct regulatory roles in the antibacterial defense response of Lasioderma serricorne, and they are significant for pest control and immune response.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Entomology
Yue Zhang, Yi Yan, Guy Smagghe, Hong Yang, Ren-huai Dai, Wen-jia Yang
Summary: This study found that AMP genes in cigarette beetles were significantly upregulated following parasitism by the ectoparasitic wasp, suggesting enhanced resistance against pathogenic microorganisms. LsCole was responsible for immune response against both Gram-negative and Gram-positive bacteria, while LsDef1 and LsDef2 were involved in defense against Gram-positive bacteria. These AMPs may have potential as antimicrobial agents.
Article
Parasitology
Hao-Chengip Wang, Qiu-Hui Wang, Biswajit Bhowmick, Yi-Xun Li, Qian Han
Summary: The study investigated the functional characterization of Ae-CLIPB15 and Ae-CLIPB22 in Ae. aegypti, revealing their critical roles in immune defense against bacterial and fungal infections through regulation of transcription factors and PO activity. These findings suggest that Ae-CLIPB15 and Ae-CLIPB22 play a specific role in the regulation of innate immunity.
PARASITES & VECTORS
(2021)
Article
Biochemistry & Molecular Biology
Xi-Ya Liu, Hui-Mei Sun, Yi-Hong Luo, Mao-Ye Li, Hai-Bing Liu, Su Liu
Summary: In this study, the role of GST genes in the detoxification of pesticides in cigarette beetles was investigated. It was found that the LsGSTE1 gene not only metabolizes the insecticide but also protects against oxidative stress. These findings suggest that LsGSTE1 could be a potential target for sustainable management of the cigarette beetle.
PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY
(2023)
Article
Agronomy
Li-Xin Ma, Rong-Tao He, Shu-Yan Yan, Wen-Jia Yang
Summary: In this study, we identified and characterized an HR3 gene (LsHR3) from the cigarette beetle and found that LsHR3 plays a critical role in insect metamorphosis and development. LsHR3 was mainly expressed in the fourth-instar larvae, prepupae, and pupae and its expression was induced by 20E. RNAi knockdown of LsHR3 disrupted the larval-pupal molting and caused mortality, indicating the importance of LsHR3-mediated 20E signaling in regulating chitin metabolism during the molting process of the cigarette beetle.
Article
Entomology
Yu-Meng Ma, Nan Chen, Jia-Yu Tan, Mao -Ye Li, Su Liu
Summary: This study identified and characterized the arginine kinase (AK) gene in the cigarette beetle, Lasioderma serricorne, an important pest species. The LsAK gene was found to be essential for larval survival, and oral delivery of double-stranded RNA targeting LsAK significantly reduced survival rates. These findings suggest that LsAK could be a viable target for RNA-interference-based pest management.
JOURNAL OF STORED PRODUCTS RESEARCH
(2022)
Article
Immunology
Qiao Jin, Yang Wang, Haodong Yin, Haobo Jiang
Summary: Insects produce phenoloxidases (POs) to kill pathogens and produce melanin. The activation of POs requires a cofactor, and this study identifies cSPH35 and cSPH242 as essential cofactors for the activation of PPO1 in Drosophila.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Physiology
Kang-Kang Xu, Yi Yan, Shu-Yan Yan, Peng-Liang Xia, Wen-Jia Yang, Can Li, Hong Yang
Summary: The study identified and characterized an Akt gene in the cigarette beetle, showing its crucial role in ovarian development, fecundity, hatchability, vitellogenin synthesis, juvenile hormone production, and carbohydrate metabolism.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Fisheries
Wei Qin, Yang Lu, Hongyu Wang, Beixiang Liu, Zuosheng Jiang, Chengxiang Zhou, Xin Huang, Xiaoling Dai, Qian Ren
Summary: In this study, a clip domain serine protease (MncSP) and its alternative transcript (MncSP-isoform) were identified from Macrobrachium nipponense, which are widely distributed in different tissues. MncSP participated in the synthesis of antimicrobial peptides (AMPs) and the activation of prophenoloxidase, as shown through expression profile analysis and RNAi experiments.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2022)
Article
Fisheries
Pattamaporn Kwankaew, Naeem Madsari, Ratiporn Thongsoi, Prapaporn Utarabhand, Phanthipha Runsaeng
Summary: This study partially characterized the function of FmclipSP and demonstrated its association with VP28. The results indicate the importance of FmclipSP in the innate immunity of F. merguiensis.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2022)
Article
Multidisciplinary Sciences
Seung Hyun Ahn, Dowoon Gu, Yongjun Koh, Hye-Sook Lee, Sung Wook Chi
Summary: By reanalysing AGO CLIP data in RNA viruses, putative AGO binding sites for siRNAs in the SARS-CoV-2 genome were delineated, and it was found that siRNAs loaded onto AGO can repress target transcripts by acting as miRNAs. Utilizing seed sequences of known antifibrotic miRNAs, potential siRNAs for treating COVID-19 were identified and validated for their activity in lung cell lines.
SCIENTIFIC REPORTS
(2021)
Article
Biochemistry & Molecular Biology
Neal T. Dittmer, Yasuaki Hiromasa, Michael R. Kanost
Summary: The insect cuticle is crucial for their survival and serves multiple functions including protection, communication, locomotion, and support. In the molting process, insects secrete molting fluid to break down and recycle their old cuticle. This study identified proteins in the molting fluid of the tobacco hornworm and categorized them based on their proposed functions, providing insights into the immune defense mechanism of molting fluid.
INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY
(2022)
Article
Immunology
Xin Zhang, Miao Li, Layla El Moussawi, Sally Saab, Shasha Zhang, Mike A. Osta, Kristin Michel
Summary: Humoral immune responses in animals are tightly controlled by regulated proteolysis, where extracellular protease cascades activate key immune proteins and enzymes. In mosquitoes, the protease network regulates melanization reactions and affects resistance against microorganisms.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2021)
Article
Entomology
Qing-Hui Zeng, Gui-Yun Long, Xi-Bin Yang, Ze-Yan Jia, Dao-Chao Jin, Hong Yang
Summary: This study investigated the role of Dicer2 in the regulation of molting and wing expansion in Sogatella furcifera. The results showed that the RNAi-mediated silencing of SfDicer2 led to wing deformities and lethal modifications in S. furcifera, which were caused by the inhibition of chitin synthesis and degradation and wing expansion genes.
Article
Engineering, Environmental
Xing Zhang, Xiurong Yang, Suhang Chen, Shuai Dong, Enzhou Liu, Hui Li, Haixia Ma, Kangzhen Xu
Summary: In this study, a novel Eu-doped ZnCo2O4 composite was successfully synthesized and used for PMS activation to degrade FOX-7. The Eu-0.4-ZnCo2O4 exhibited remarkable PMS activation performance, about 5.67 times higher than undoped ZnCo2O4. The enhanced catalytic performance was attributed to abundant oxygen vacancies (OVs) that promoted carrier separation and accelerated the cycling of the Co3+/Co2+ redox pairs. The study also established a relationship between the Co3+/Co2+ and oxygen defects/lattice oxygen (O-Def/O-Lat) ratios and catalytic activity.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Computer Science, Artificial Intelligence
Jianyang Cai, Haidong Yang, Kangkang Xu
Summary: The novel energy consumption prediction model for chillers, ICA-DE-SVM, based on an improved support vector machine, provides an important means to reduce building energy consumption. By optimizing the penalty coefficient and kernel function width of SVM using the imperialist competitive algorithm (ICA), the model greatly improves the generalization ability and prediction accuracy. The application of differential mutation from differential evolution (DE) further enhances population diversity and improves prediction results.
JOURNAL OF INTELLIGENT & FUZZY SYSTEMS
(2023)
Article
Materials Science, Multidisciplinary
Hongjie Ma, Yujiang Wang, Bo Wang, Jian Ding, Kangkang Xu, Xingchuan Xia, Shicheng Wei
Summary: Promising microwave absorbers with thin, light, wide, strong and high stability characteristics can be achieved by designing the microstructure and manipulating the components. In this study, 3D flower-like MoS2 decorated by hollow CoFe2O4 nanospheres was synthesized using a two-step hydrothermal method. The synthesized 1T/2H MoS2@CFO composites exhibited excellent microwave absorption performances, attributed to the synergistic effects of magnetic loss, dielectric loss, impedance matching, polarization relaxation, and multi-scattering/reflection.
JOURNAL OF MATERIALS SCIENCE
(2023)
Article
Engineering, Chemical
Xing Zhang, Suhang Chen, Haidong Luo, Zhenhua Tang, Enzhou Liu, Zhao Qin, Kangzhen Xu
Summary: A novel F-g-C3N4/MnxCo3_xO4 composite was successfully synthesized by a one-step hydrothermal method for the degradation of FOX-7. F doping narrowed the band gap and enhanced the light absorption range and separation of photogenerated electron-hole pairs. The catalytic activity of F-CN/MCO was higher than that of MCO and CN/MCO due to the unique materials morphology and the synergistic effect of photocatalytic and chemical catalytic driven PMS activation. Quenching experiments and EPR confirmed the involvement of both radical and non-radical pathways, with singlet oxygen (1O2) identified as the predominant active species. The synergy between Co2+/Co3+ and Mn2+/Mn3+ couples enhanced electron transfer and redox potential, promoting the photocatalytic activation of PMS. This work provides a novel approach for designing efficient catalysts to promote the redox behavior of metal species in sulfate radical-based advanced oxidation processes.
SEPARATION AND PURIFICATION TECHNOLOGY
(2023)
Article
Geosciences, Multidisciplinary
Kang-kang Xu, Hong-wei Sun, Wei Xie, Fu-qing He, Xiao-yang Liu, Kai Sun, Sheng-fei He, Xing-yuan Wu, Peng-hui Gong, Godfrey Machumu
Summary: Tanzania, an eastern African country with predominantly agricultural economy, has promising potential for developing cultivated land. Boron (B), Zinc (Zn), and Selenium (Se) are essential micronutrients for both plants and human body, and their concentrations and distributions in cultivated land soil are important for guiding agricultural production. In a low-density geochemical survey conducted at a scale of 1:1000000 in Tanzania, it was found that the concentrations of B, Zn, and Se in stream sediments are low and heterogeneously distributed. The concentrations of B, Zn, and Se in these regions are insufficient overall but enriched locally compared to national background values. The positive correlation between element concentrations in stream sediments and soil, due to their similar sources, is essential in agriculture application. Based on the provided low-density geochemical data and maps, regions rich in Se were identified in Tanzania, which can be utilized for developing Se-rich industries. The paper concludes that geochemical survey is a powerful tool for evaluating cultivated land, managing agriculture, and developing land.
Article
Nanoscience & Nanotechnology
Zhechen Fan, Maogen Zhu, Yuting Fang, Kaiwen Qi, Kangli Xu, Weiwei Wang, Qianyao Wu, Yongchun Zhu
Summary: The plating and stripping process of lithium metal within a graphene skeleton decorated with silver nanoparticles was investigated in this study. The graphene skeleton had micron-level pores and superior elastic property, which confined the metal deposition and provided continuous volume-derived stress. This stress-regulating strategy improved the morphology and reversibility of lithium metal anodes, showing its potential significance for other conversion electrodes.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Multidisciplinary
Weiyuan Huang, Jimin Qiu, Yuchen Ji, Wenguang Zhao, Zihang Dong, Kai Yang, Ming Yang, Qindong Chen, Mingjian Zhang, Cong Lin, Kang Xu, Luyi Yang, Feng Pan
Summary: By using LiCoO2 as a redox mediator, the decomposition of Na2CO3 can be catalyzed, enabling the effective harvest of electrochemical energy from insulating compounds and unlocking their potential capacity for energy storage.
Article
Engineering, Chemical
Kangkang Xu, Yajun Fan, Chengjiu Zhu, Guangdong Tian, Luoke Hu
Summary: This paper proposes a novel multiple spatiotemporal modeling method based on incremental spatiotemporal broad learning and adaptive ensemble learning for temperature prediction of lithium-ion batteries (LIBs). The thermal process is identified through density peak clustering and modeled using a spatial kernel function. An adaptive ensemble learning is used to obtain multiple models, and incremental learning is performed to improve the adaptive ability of the model. Experimental results validate the higher accuracy and efficiency of the proposed method compared to traditional global spatiotemporal modeling.
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
(2023)
Article
Entomology
Yi Yan, Dong-Dong Qin, Hong Yang, Kang-Kang Xu, Can Li, Wen-Jia Yang
Summary: This study identified the post-transcriptional pathway of LsAkt in L. serricorne and identified the binding sites of miR-9c-5p and novel-mir50 in the coding sequences of LsAkt. miR-9c-5p and novel-mir50 downregulated the expression of LsAkt, leading to inhibited reproduction and ovarian development in L. serricorne. It was also found that bovine insulin could regulate miR-9c-5p/novel-mir50 expression and rescue the reproductive defects caused by their overexpression.
Article
Chemistry, Multidisciplinary
Zhenhai Li, Jinchen Wei, Jialin Meng, Yongkai Liu, Jiajie Yu, Tianyu Wang, Kangli Xu, Pei Liu, Hao Zhu, Shiyou Chen, Qing-Qing Sun, David Wei Zhang, Lin Chen
Summary: The influence of aluminum content in HfAlO thin films on the ferroelectric characteristics of HfAlO-based FTJs was investigated. The HfAlO device with a Hf/Al ratio of 34:1 showed the highest remanent polarization and excellent memory characteristics, indicating the best ferroelectricity among the investigated devices. First-principal analyses confirmed that the HfAlO thin films with a Hf/Al ratio of 34:1 promoted the formation of the orthorhombic phase and reduced alumina impurities, enhancing the ferroelectricity of the device.
Article
Multidisciplinary Sciences
Jijian Xu, Jiaxun Zhang, Travis P. Pollard, Qingdong Li, Sha Tan, Singyuk Hou, Hongli Wan, Fu Chen, Huixin He, Enyuan Hu, Kang Xu, Xiao-Qing Yang, Oleg Borodin, Chunsheng Wang
Summary: This study introduces an electrolyte design strategy based on soft solvents, which can meet various requirements of the widely used LiNi0.8Mn0.1Co0.1O2 (NMC811)||graphite lithium-ion batteries, such as high voltage, fast charging, wide temperature range for charging/discharging, and non-flammability. This design principle can also prevent lithium plating at low temperatures.
Review
Biochemistry & Molecular Biology
Yue Chen, Yadong Wang, Yawei Fu, Yulong Yin, Kang Xu
Summary: Aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor that plays a crucial role in regulating intestinal immunity and inflammation. Activation of AHR can have beneficial effects on the gut, but excessive or sustained activation can lead to immune dysregulation and intestinal diseases. The synthetic ligand TCDD has significant immunotoxic effects and impairs the intestinal epithelial barrier when it activates AHR.
CELL AND BIOSCIENCE
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yuhua Wang, Ye Liu, Na Li, Kang Xu, Wanchun Zhang
Summary: This retrospective study compared the SUVmax and TBR of parathyroid lesions in early-phase and delayed-phase SPECT/CT in patients with SHPT. Results showed significant differences in SUVmax and TBR between the two phases, indicating the need for delayed-phase SPECT/CT for better image contrast in SHPT patients.
Article
Food Science & Technology
Bangqiang Zhu, Hu Gao, Fang Yang, Yiyang Li, Qiaoyue Yang, Yinchang Liao, Haimin Guo, Kang Xu, Zhiqiang Tang, Ning Gao, Yuebo Zhang, Jun He
Summary: This study aimed to investigate the flavor characteristics of Ningxiang pigs, Duroc pigs, and their crosses using electronic nose and gas chromatography-mass spectrometry analysis. Aldehydes were found to be the main volatile substances in all three populations, with significant differences in benzaldehyde content. The flavor substances of the Duroc x Ningxiang crosses were similar to Ningxiang pigs and exhibited certain heterosis in flavor characteristics.
Article
Green & Sustainable Science & Technology
Jun Li, Jing Peng, Kuo Zeng, Dian Zhong, Kang Xu, Vasilevich Sergey Vladimirovich, Ange Nzihou, Haiping Yang, Hanping Chen
Summary: Pyrolysis of algae in molten carbonates driven by concentrated solar energy is proposed as an economical and environmentally friendly method to obtain capacitive carbon for supercapacitors. The effects of different molten carbonates on pyrolysis process and electrochemical performance are investigated. Na2CO3-K2CO3 leads to a high carbon yield and superior microstructure at around 900 degrees C, resulting in a capacitive carbon with high specific capacitance and capacitance retention.
JOURNAL OF CLEANER PRODUCTION
(2023)