A Robust Model System for Retinal Hypoxia: Live Imaging of Calcium Dynamics and Gene Expression Studies in Primary Human Mixed Retinal Culture

Hypoxia and Hypoxia-Inducible Factors in Kidney Injury and Repair

(2019) Shaoqun Shu et al.   Cells

Merging organoid and organ-on-a-chip technology to generate complex multi-layer tissue models in a human retina-on-a-chip platform

(2019) Kevin Achberger et al.   eLife

Role of Inflammation in Diabetic Retinopathy

(2018) Anne Rübsam et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Disease Modeling Using 3D Organoids Derived from Human Induced Pluripotent Stem Cells

(2018) Beatrice Ho et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A 3D human triculture system modeling neurodegeneration and neuroinflammation in Alzheimer’s disease

(2018) Joseph Park et al.   NATURE NEUROSCIENCE

Human induced pluripotent stem cells generate light responsive retinal organoids with variable and nutrient dependent efficiency

(2018) Dean Hallam et al.   STEM CELLS

Confocal Imaging and k-Means Clustering of GABAB and mGluR Mediated Modulation of Ca2+ Spiking in Hippocampal Neurons

(2018) Sarpras Swain et al.   ACS Chemical Neuroscience

Reactive Oxygen Species-Mediated Damage of Retinal Neurons: Drug Development Targets for Therapies of Chronic Neurodegeneration of the Retina

(2018) Landon Rohowetz et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

In Vivo Two-Photon Imaging of Astrocytes in GFAP-GFP Transgenic Mice

(2017) Dongjun Guo et al.   PLoS One

Two different mechanosensitive calcium responses in Müller glial cells of the guinea pig retina: Differential dependence on purinergic receptor signaling

(2016) Silke Agte et al.   GLIA

Glia–neuron interactions in the mammalian retina

(2016) Elena Vecino et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Glia-Neuron Interactions in the Retina Can Be Studied in Cocultures of Müller Cells and Retinal Ganglion Cells

(2016) D. M. Skytt et al.   Biomed Research International

Microglial phagocytosis of living photoreceptors contributes to inherited retinal degeneration

(2015) L. Zhao et al.   EMBO Molecular Medicine

Neuroinflammatory responses in diabetic retinopathy

(2015) Ying Yu et al.   Journal of Neuroinflammation

Primary Retinal Cultures as a Tool for Modeling Diabetic Retinopathy: An Overview

(2015) Andrea Matteucci et al.   Biomed Research International

Neuron-glia signaling in developing retina mediated by neurotransmitter spillover

(2015) Juliana M Rosa et al.   eLife

High Glucose Alters Retinal Astrocytes Phenotype through Increased Production of Inflammatory Cytokines and Oxidative Stress

(2014) Eui Seok Shin et al.   PLoS One

Expression and significance of HIF-1 α and VEGF in rats with diabetic retinopathy

(2014) Hong-Tao Yan et al.   Asian Pacific Journal of Tropical Medicine

Hypoxia induces cell damage via oxidative stress in retinal epithelial cells

(2013) F. Cervellati et al.   FREE RADICAL RESEARCH

Retinal Microglial Activation and Inflammation Induced by Amadori-Glycated Albumin in a Rat Model of Diabetes

(2011) A. S. Ibrahim et al.   DIABETES

Activation of retinal microglia rather than microglial cell density correlates with retinal neovascularization in the mouse model of oxygen-induced retinopathy

(2011) Franziska Fischer et al.   Journal of Neuroinflammation

Neurodegeneration in glaucoma: progression and calcium-dependent intracellular mechanisms

(2010) S.D. Crish et al.   NEUROSCIENCE

High glucose enhances intracellular Ca2+ responses triggered by purinergic stimulation in retinal neurons and microglia

(2009) Tiago de Oliveira Simões Pereira et al.   BRAIN RESEARCH

Synchronous Hyperactivity and Intercellular Calcium Waves in Astrocytes in Alzheimer Mice

(2009) K. V. Kuchibhotla et al.   SCIENCE

Live Imaging of Neuronal Degradation by Microglia Reveals a Role for v0-ATPase a1 in Phagosomal Fusion In Vivo

(2008) Francesca Peri et al.   CELL

Thoughts on limitations of animal models

(2008) Thomas Hartung   PARKINSONISM & RELATED DISORDERS