Insulin-Like Growth Factor-1 Down-Regulates the Phosphorylation of FXYD1 and Rescues Behavioral Deficits in a Mouse Model of Rett Syndrome

Correcting deregulated Fxyd1 expression rescues deficits in neuronal arborization and potassium homeostasis in MeCP2 deficient male mice

(2018) Valerie Matagne et al.   BRAIN RESEARCH

Rett syndrome: insights into genetic, molecular and circuit mechanisms

(2018) Jacque P. K. Ip et al.   NATURE REVIEWS NEUROSCIENCE

The therapeutic potential of insulin-like growth factor-1 in central nervous system disorders

(2016) Jesse Costales et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Expression of nuclear Methyl-CpG binding protein 2 (Mecp2) is dependent on neuronal stimulation and application of Insulin-like growth factor 1

(2016) Daniela Tropea et al.   NEUROSCIENCE LETTERS

Protein kinase C beta II suppresses colorectal cancer by regulating IGF-1 mediated cell survival

(2016) Catríona M. Dowling et al.   Oncotarget

Insulin-Like Growth Factor 1 and Related Compounds in the Treatment of Childhood-Onset Neurodevelopmental Disorders

(2016) Cyrus Vahdatpour et al.   Frontiers in Neuroscience

Dysregulation of the IGF-I/PI3K/AKT/mTOR signaling pathway in autism spectrum disorders

(2014) Jianling Chen et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Functional recovery with recombinant human IGF1 treatment in a mouse model of Rett Syndrome

(2014) Jorge Castro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Safety, pharmacokinetics, and preliminary assessment of efficacy of mecasermin (recombinant human IGF-1) for the treatment of Rett syndrome

(2014) O. S. Khwaja et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Insulin-like growth factor-1 rescues synaptic and motor deficits in a mouse model of autism and developmental delay

(2013) Ozlem Bozdagi et al.   Molecular Autism

Correcting deregulated Fxyd1 expression ameliorates a behavioral impairment in a mouse model of Rett syndrome

(2012) Valerie Matagne et al.   BRAIN RESEARCH

PKCη is a negative regulator of AKT inhibiting the IGF-I induced proliferation

(2012) Galit Shahaf et al.   EXPERIMENTAL CELL RESEARCH

Reduced AKT/mTOR signaling and protein synthesis dysregulation in a Rett syndrome animal model

(2011) Sara Ricciardi et al.   HUMAN MOLECULAR GENETICS

Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes

(2010) Hsiao-Tuan Chao et al.   NATURE

Partial reversal of Rett Syndrome-like symptoms in MeCP2 mutant mice

(2009) Daniela Tropea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA