The Natural Product Lepidiline A as an N-Heterocyclic Carbene Ligand Precursor in Complexes of the Type [Ir(cod)(NHC)PPh3)]X: Synthesis, Characterisation, and Application in Hydrogen Isotope Exchange Catalysis

Highlights of aliphatic C (sp3 )-H Hydrogen Isotope Exchange Reactions

(2019) Mégane Valero et al.   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

Highlights of C (sp2 )-H hydrogen isotope Exchange Reactions

(2019) David Hesk   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

Recent Advances in Iridium(I) Catalysis towards Directed Hydrogen Isotope Exchange

(2019) William J. Kerr et al.   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

Deuterium- and Tritium-Labelled Compounds: Applications in the Life Sciences

(2018) Jens Atzrodt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

C−H Functionalisation for Hydrogen Isotope Exchange

(2018) Jens Atzrodt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis and Cytotoxicity Studies of Novel NHC*-Gold(I) Complexes Derived from Lepidiline A

(2018) Danielle Curran et al.   MOLECULES

Site-Selective Deuteration of N-Heterocycles via Iridium-Catalyzed Hydrogen Isotope Exchange

(2017) William J. Kerr et al.   ACS Catalysis

Iridium-catalysed ortho-H/D and -H/T exchange under basic conditions: C–H activation of unprotected tetrazoles

(2016) William J. Kerr et al.   CHEMICAL COMMUNICATIONS

Hydrogen isotope exchange with highly active iridium(I) NHC/phosphine complexes: a comparative counterion study

(2016) William J. Kerr et al.   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

Expanded applicability of iridium(I) NHC/phosphine catalysts in hydrogen isotope exchange processes with pharmaceutically-relevant heterocycles

(2015) Jens Atzrodt et al.   TETRAHEDRON

The Synthesis of Highly Active Iridium(I) Complexes and their Application in Catalytic Hydrogen Isotope Exchange

(2014) Jack A. Brown et al.   ADVANCED SYNTHESIS & CATALYSIS

Iridium(I)-Catalyzed Regioselective CH Activation and Hydrogen-Isotope Exchange of Non-aromatic Unsaturated Functionality

(2014) William J. Kerr et al.   CHEMISTRY-A EUROPEAN JOURNAL

Anion effects to deliver enhanced iridium catalysts for hydrogen isotope exchange processes

(2014) Alan R. Kennedy et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Iridium-Catalyzed C–H Activation and Deuteration of Primary Sulfonamides: An Experimental and Computational Study

(2014) William J. Kerr et al.   ACS Catalysis

Synthesis and Reactivity of New Bis(N-heterocyclic carbene) Iridium(I) Complexes

(2013) David J. Nelson et al.   INORGANIC CHEMISTRY

Application of neutral iridium(I)N-heterocyclic carbene complexes inortho-directed hydrogen isotope exchange

(2013) Alison R. Cochrane et al.   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

Heavy drugs draw heavy interest from pharma backers

(2013) Alla Katsnelson   NATURE MEDICINE

Radiolabeled Absorption, Distribution, Metabolism, and Excretion Studies in Drug Development: Why, When, and How?

(2012) Natalia Penner et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Use of Radiolabeled Compounds in Drug Metabolism and Pharmacokinetic Studies

(2012) Emre M. Isin et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Structure-Activity Relationship in the Iridium-Catalyzed Isomerization of Primary Allylic Alcohols

(2012) Luca Mantilli et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

LabileN-Heterocyclic Carbene Complexes of Iridium

(2009) Olga Torres et al.   ORGANOMETALLICS

Highly active iridium(i) complexes for catalytic hydrogen isotope exchange

(2008) Jack A. Brown et al.   CHEMICAL COMMUNICATIONS

Synthesis, characterization and catalytic activity of saturated and unsaturated N-heterocyclic carbene iridium(i) complexes

(2008) Yung-Hung Chang et al.   DALTON TRANSACTIONS