Long noncoding RNA DUXAP8 contributes to the progression of hepatocellular carcinoma via regulating miR‐422a/PDK2 axis

MicroRNA‐214 suppresses cell proliferation and migration and cell metabolism by targeting PDK2 and PHF6 in hepatocellular carcinoma

(2019) Qiangfeng Yu et al.   CELL BIOLOGY INTERNATIONAL

Up-regulated long non-coding RNA DUXAP8 promotes cell growth through repressing Krüppel-like factor 2 expression in human hepatocellular carcinoma

(2019) Hao Jiang et al.   OncoTargets and Therapy

MiR-422a regulates cellular metabolism and malignancy by targeting pyruvate dehydrogenase kinase 2 in gastric cancer

(2018) Zhongyuan He et al.   Cell Death & Disease

PDK2 induces cisplatin-resistance in lung adenocarcinoma via transcriptional regulation of CNNM3

(2018) Tinghua Hu et al.   JOURNAL OF DRUG TARGETING

Long Non-Coding RNA DUXAP8 Enhances Renal Cell Carcinoma Progression via Downregulating miR-126

(2018) Tao Huang et al.   MEDICAL SCIENCE MONITOR

The end of almost 10 years of negative RCTs in advanced hepatocellular carcinoma

(2017) Jean-Charles Nault   LANCET

MicroRNA-138 inhibits cell proliferation in hepatocellular carcinoma by targeting Sirt1

(2017) Jia Luo et al.   ONCOLOGY REPORTS

miR-422a Inhibits Glioma Proliferation and Invasion by Targeting IGF1 and IGF1R

(2017) Haiyang Wang et al.   ONCOLOGY RESEARCH

The diagnosis and treatment of hepatocellular carcinoma

(2017) Justin Hartke et al.   SEMINARS IN DIAGNOSTIC PATHOLOGY

The long non-coding RNA MALAT1 promotes the migration and invasion of hepatocellular carcinoma by sponging miR-204 and releasing SIRT1

(2017) Zhouhua Hou et al.   TUMOR BIOLOGY

Liquid biopsy in patients with hepatocellular carcinoma: Circulating tumor cells and cell-free nucleic acids

(2017) Wataru Okajima et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Suppression of pyruvate dehydrogenase kinase-2 re-sensitizes paclitaxel-resistant human lung cancer cells to paclitaxel

(2017) Hong Sun et al.   Oncotarget

Activation of mitochondrial oxidation by PDK2 inhibition reverses cisplatin resistance in head and neck cancer

(2016) Jong-Lyel Roh et al.   CANCER LETTERS

A Positive Feedback Loop of lncRNA- PVT1 and FOXM1 Facilitates Gastric Cancer Growth and Invasion

(2016) Mi-die Xu et al.   CLINICAL CANCER RESEARCH

The long noncoding RNA HOTAIR activates autophagy by upregulating ATG3 and ATG7 in hepatocellular carcinoma

(2016) Liang Yang et al.   Molecular BioSystems

Expression and function of microRNA-27b in hepatocellular carcinoma

(2016) SHUJIE HE et al.   Molecular Medicine Reports

MiR-422a promotes loco-regional recurrence by targeting NT5E/CD73 in head and neck squamous cell carcinoma

(2016) Nathalie Bonnin et al.   Oncotarget

The Long Noncoding RNA lncTCF7 Promotes Self-Renewal of Human Liver Cancer Stem Cells through Activation of Wnt Signaling

(2015) Yanying Wang et al.   Cell Stem Cell

Double-negative feedback loop between MicroRNA-422a and forkhead box (FOX)G1/Q1/E1 regulates hepatocellular carcinoma tumor growth and metastasis

(2015) Jin Zhang et al.   HEPATOLOGY

PDK2-mediated alternative splicing switches Bnip3 from cell death to cell survival

(2015) Hongying Gang et al.   JOURNAL OF CELL BIOLOGY

Long noncoding RNA GAS5 suppresses the migration and invasion of hepatocellular carcinoma cells via miR-21

(2015) Litian Hu et al.   TUMOR BIOLOGY

Functions of lncRNA HOTAIR in lung cancer

(2014) Gregory Loewen et al.   Journal of Hematology & Oncology

MicroRNAs and long non-coding RNAs: prospects in diagnostics and therapy of cancer

(2013) Nina Hauptman et al.   Radiology and Oncology

Hepatocellular carcinoma

(2012) Alejandro Forner et al.   LANCET

p53 Negatively Regulates Transcription of the Pyruvate Dehydrogenase Kinase Pdk2

(2011) T. Contractor et al.   CANCER RESEARCH

Advantages of genomic complexity: bioinformatics opportunities in microRNA cancer signatures: Figure 1

(2011) Yves A Lussier et al.   JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION

MicroRNAs and Cancer: Short RNAs Go a Long Way

(2009) Andrea Ventura et al.   CELL

Evolution and Functions of Long Noncoding RNAs

(2009) Chris P. Ponting et al.   CELL

Causes and consequences of microRNA dysregulation in cancer

(2009) Carlo M. Croce   NATURE REVIEWS GENETICS