Integration of transcriptome-wide association study and messenger RNA expression profile to identify genes associated with osteoarthritis

NFAT1 protects articular cartilage against osteoarthritic degradation by directly regulating transcription of specific anabolic and catabolic genes

(2019) M. Zhang et al.   Bone & Joint Research

GWAS for quantitative resistance phenotypes in Mycobacterium tuberculosis reveals resistance genes and regulatory regions

(2019) Maha R. Farhat et al.   Nature Communications

Transcriptome-wide association studies accounting for colocalization using Egger regression

(2018) Richard Barfield et al.   GENETIC EPIDEMIOLOGY

Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis

(2018) Eleni Zengini et al.   NATURE GENETICS

The role of skeletal muscle in the pathophysiology and management of knee osteoarthritis

(2018) Priathashini Krishnasamy et al.   RHEUMATOLOGY

Use of integrative epigenetic and mRNA expression analyses to identify significantly changed genes and functional pathways in osteoarthritic cartilage

(2018) A. He et al.   Bone & Joint Research

Global transcriptome analysis to identify critical genes involved in the pathology of osteoarthritis

(2018) X. Zhang et al.   Bone & Joint Research

Identification of transcription factors responsible for dysregulated networks in human osteoarthritis cartilage by global gene expression analysis

(2018) K.M. Fisch et al.   OSTEOARTHRITIS AND CARTILAGE

Gene expression imputation identifies candidate genes and susceptibility loci associated with cutaneous squamous cell carcinoma

(2018) Nilah M. Ioannidis et al.   Nature Communications

Transcriptome-wide association study identifies multiple genes and pathways associated with pancreatic cancer

(2018) Liuyun Gong et al.   Cancer Medicine

Expression quantitative trait loci (eQTLs) in human placentas suggest developmental origins of complex diseases

(2017) Shouneng Peng et al.   HUMAN MOLECULAR GENETICS

Functional mapping and annotation of genetic associations with FUMA

(2017) Kyoko Watanabe et al.   Nature Communications

Identification of upstream regulators for synovial expression signature genes in osteoarthritis

(2016) Qi Fei et al.   JOINT BONE SPINE

Integrative approaches for large-scale transcriptome-wide association studies

(2016) Alexander Gusev et al.   NATURE GENETICS

MicroRNAs: exploring new horizons in osteoarthritis

(2016) M. Nugent   OSTEOARTHRITIS AND CARTILAGE

Silencing of microRNA-138-5p promotes IL-1β-induced cartilage degradation in human chondrocytes by targeting FOXC1

(2016) Y. Yuan et al.   Bone & Joint Research

Osteoarthritis

(2016) Johanne Martel-Pelletier et al.   Nature Reviews Disease Primers

Osteoarthritis

(2016) Duarte Pereira et al.   Acta Medica Portuguesa

Changes in peripheral blood immune cell composition in osteoarthritis

(2015) F. Ponchel et al.   OSTEOARTHRITIS AND CARTILAGE

The involvement of follistatin-like protein 1 in osteoarthritis by elevating NF-κB-mediated inflammatory cytokines and enhancing fibroblast like synoviocyte proliferation

(2015) Su Ni et al.   ARTHRITIS RESEARCH & THERAPY

Follistatin-like protein 1 regulates chondrocyte proliferation and chondrogenic differentiation of mesenchymal stem cells

(2014) Yury Chaly et al.   ANNALS OF THE RHEUMATIC DISEASES

Heritability and genomics of gene expression in peripheral blood

(2014) Fred A Wright et al.   NATURE GENETICS

Cardiovascular risk factors in 2011 and secular trends since 2007: The Cardiovascular Risk in Young Finns Study

(2014) Joel Nuotio et al.   SCANDINAVIAN JOURNAL OF PUBLIC HEALTH

Characterization of the Cartilage DNA Methylome in Knee and Hip Osteoarthritis

(2014) Michael D. Rushton et al.   Arthritis & Rheumatology

Transcriptome and genome sequencing uncovers functional variation in humans

(2013) Tuuli Lappalainen et al.   NATURE

The Genotype-Tissue Expression (GTEx) project

(2013) John Lonsdale et al.   NATURE GENETICS

Polygenic Modeling with Bayesian Sparse Linear Mixed Models

(2013) Xiang Zhou et al.   PLoS Genetics

Identification of the pathogenic pathways in osteoarthritic hip cartilage: commonality and discord between hip and knee OA

(2012) Y. Xu et al.   OSTEOARTHRITIS AND CARTILAGE

Global quantification of mammalian gene expression control

(2011) Björn Schwanhäusser et al.   NATURE

Large Scale Replication Study of the Association between HLA Class II/BTNL2 Variants and Osteoarthritis of the Knee in European-Descent Populations

(2011) Ana M. Valdes et al.   PLoS One

MicroRNA-138 regulates osteogenic differentiation of human stromal (mesenchymal) stem cells in vivo

(2011) T. Eskildsen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Follistatin-like protein 1: a serum biochemical marker reflecting the severity of joint damage in patients with osteoarthritis

(2011) Yuji Wang et al.   ARTHRITIS RESEARCH & THERAPY

New Sequence Variants in HLA Class II/III Region Associated with Susceptibility to Knee Osteoarthritis Identified by Genome-Wide Association Study

(2010) Masahiro Nakajima et al.   PLoS One

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Differential expression of GADD45β in normal and osteoarthritic cartilage: Potential role in homeostasis of articular chondrocytes

(2008) Kosei Ijiri et al.   ARTHRITIS AND RHEUMATISM

Gene expression profile of the bone microenvironment in human fragility fracture bone

(2008) B. Hopwood et al.   BONE

Cohort Profile: The Cardiovascular Risk in Young Finns Study

(2008) O. T Raitakari et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH