NANOG and LIN28 dramatically improve human cell reprogramming by modulating LIN41 and canonical WNT activities

TCF7L1 suppresses primitive streak gene expression to support human embryonic stem cell pluripotency

(2018) Robert A. Sierra et al.   DEVELOPMENT

Wnt/β-Catenin/TCF Pathway Is a Phase-Dependent Promoter of Colony Formation and Mesendodermal Differentiation During Human Somatic Cell Reprogramming

(2018) Ricardo Raúl Cevallos et al.   STEM CELLS

Enhanced human somatic cell reprogramming efficiency by fusion of the MYC transactivation domain and OCT4

(2017) Ling Wang et al.   Stem Cell Research

The WNT target SP5 negatively regulates WNT transcriptional programs in human pluripotent stem cells

(2017) Ian J. Huggins et al.   Nature Communications

Glis family proteins are differentially implicated in the cellular reprogramming of human somatic cells

(2017) Seo-Young Lee et al.   Oncotarget

Wnt/Tcf1 pathway restricts embryonic stem cell cycle through activation of the Ink4/Arf locus

(2017) Anchel De Jaime-Soguero et al.   PLoS Genetics

LIN28 Regulates Stem Cell Metabolism and Conversion to Primed Pluripotency

(2016) Jin Zhang et al.   Cell Stem Cell

Heatmapper: web-enabled heat mapping for all

(2016) Sasha Babicki et al.   NUCLEIC ACIDS RESEARCH

Transcriptional Control of Somatic Cell Reprogramming

(2016) Yan Xu et al.   TRENDS IN CELL BIOLOGY

Integrative Analyses of Human Reprogramming Reveal Dynamic Nature of Induced Pluripotency

(2015) Davide Cacchiarelli et al.   CELL

The let-7 microRNA Directs Vulval Development through a Single Target

(2015) Matyas Ecsedi et al.   DEVELOPMENTAL CELL

LIN28 cooperates with WNT signaling to drive invasive intestinal and colorectal adenocarcinoma in mice and humans

(2015) Ho-Chou Tu et al.   GENES & DEVELOPMENT

N-cadherin promotes epithelial-mesenchymal transition and cancer stem cell-like traits via ErbB signaling in prostate cancer cells

(2015) MIN WANG et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Choices for Induction of Pluripotency: Recent Developments in Human Induced Pluripotent Stem Cell Reprogramming Strategies

(2015) Marinka Brouwer et al.   Stem Cell Reviews and Reports

DPPA5 Supports Pluripotency and Reprogramming by Regulating NANOG Turnover

(2015) Xu Qian et al.   STEM CELLS

Choices for Induction of Pluripotency: Recent Developments in Human Induced Pluripotent Stem Cell Reprogramming Strategies

(2015) Marinka Brouwer et al.   Stem Cell Reviews and Reports

Mechanisms underlying the formation of induced pluripotent stem cells

(2015) Federico González et al.   Wiley Interdisciplinary Reviews-Developmental Biology

Regulation of Induced Pluripotent Stem (iPS) Cell Induction by Wnt/β-Catenin Signaling

(2014) Peilin Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genome-wide characterization of the routes to pluripotency

(2014) Samer M. I. Hussein et al.   NATURE

The WNT receptor FZD7 is required for maintenance of the pluripotent state in human embryonic stem cells

(2014) A. Fernandez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of pluripotency in human somatic cells via a transient state resembling primitive streak-like mesendoderm

(2014) Kazutoshi Takahashi et al.   Nature Communications

β-Catenin Fluctuates in Mouse ESCs and Is Essential for Nanog-Mediated Reprogramming of Somatic Cells to Pluripotency

(2014) Lucia Marucci et al.   Cell Reports

A Rare Human Syndrome Provides Genetic Evidence that WNT Signaling Is Required for Reprogramming of Fibroblasts to Induced Pluripotent Stem Cells

(2014) Jason Ross et al.   Cell Reports

The let-7/LIN-41 Pathway Regulates Reprogramming to Human Induced Pluripotent Stem Cells by Controlling Expression of Prodifferentiation Genes

(2013) Kathleen A. Worringer et al.   Cell Stem Cell

Tcf7l1 prepares epiblast cells in the gastrulating mouse embryo for lineage specification

(2013) J. A. Hoffman et al.   DEVELOPMENT

The Wnt- -catenin pathway represses let-7 microRNA expression through transactivation of Lin28 to augment breast cancer stem cell expansion

(2013) W.-Y. Cai et al.   JOURNAL OF CELL SCIENCE

Maturation, not initiation, is the major roadblock during reprogramming toward pluripotency from human fibroblasts

(2013) K. Tanabe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of DPPA4 and DPPA2 as a novel family of pluripotency-related oncogenes

(2013) Po-Yuan Tung et al.   STEM CELLS

Modulation of β-catenin function maintains mouse epiblast stem cell and human embryonic stem cell self-renewal

(2013) Hoon Kim et al.   Nature Communications

Stage-Specific Regulation of Reprogramming to Induced Pluripotent Stem Cells by Wnt Signaling and T Cell Factor Proteins

(2013) Ritchie Ho et al.   Cell Reports

WNT3 Is a Biomarker Capable of Predicting the Definitive Endoderm Differentiation Potential of hESCs

(2013) Wei Jiang et al.   Stem Cell Reports

Facilitators and Impediments of the Pluripotency Reprogramming Factors' Initial Engagement with the Genome

(2012) Abdenour Soufi et al.   CELL

A Molecular Roadmap of Reprogramming Somatic Cells into iPS Cells

(2012) Jose M. Polo et al.   CELL

Single-Cell Expression Analyses during Cellular Reprogramming Reveal an Early Stochastic and a Late Hierarchic Phase

(2012) Yosef Buganim et al.   CELL

A Late Transition in Somatic Cell Reprogramming Requires Regulators Distinct from the Pluripotency Network

(2012) Azadeh Golipour et al.   Cell Stem Cell

Esrrb Is a Pivotal Target of the Gsk3/Tcf3 Axis Regulating Embryonic Stem Cell Self-Renewal

(2012) Graziano Martello et al.   Cell Stem Cell

Precise Regulation of Porcupine Activity Is Required for Physiological Wnt Signaling

(2012) Kyle D. Proffitt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Assessing iPSC reprogramming methods for their suitability in translational medicine

(2012) Mahendra S. Rao et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Chromatin-modifying enzymes as modulators of reprogramming

(2012) Tamer T. Onder et al.   NATURE

Wnt/ -catenin signaling promotes differentiation, not self-renewal, of human embryonic stem cells and is repressed by Oct4

(2012) K. C. Davidson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Secreted and Transmembrane Wnt Inhibitors and Activators

(2012) C.-M. Cruciat et al.   Cold Spring Harbor Perspectives in Biology

Porcupine homolog is required for canonical Wnt signaling and gastrulation in mouse embryos

(2011) Steffen Biechele et al.   DEVELOPMENTAL BIOLOGY

Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1

(2011) Momoko Maekawa et al.   NATURE

T-cell factor 3 (Tcf3) deletion increases somatic cell reprogramming by inducing epigenome modifications

(2011) F. Lluis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deletion of mouse Porcn blocks Wnt ligand secretion and reveals an ectodermal etiology of human focal dermal hypoplasia/Goltz syndrome

(2011) J. J. Barrott et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Mesenchymal-to-Epithelial Transition Initiates and Is Required for the Nuclear Reprogramming of Mouse Fibroblasts

(2010) Ronghui Li et al.   Cell Stem Cell

Functional Genomics Reveals a BMP-Driven Mesenchymal-to-Epithelial Transition in the Initiation of Somatic Cell Reprogramming

(2010) Payman Samavarchi-Tehrani et al.   Cell Stem Cell

Opposing microRNA families regulate self-renewal in mouse embryonic stem cells

(2010) Collin Melton et al.   NATURE

Nanog Is the Gateway to the Pluripotent Ground State

(2009) Jose Silva et al.   CELL

Direct cell reprogramming is a stochastic process amenable to acceleration

(2009) Jacob Hanna et al.   NATURE

Live cell imaging distinguishes bona fide human iPS cells from partially reprogrammed cells

(2009) Elayne M Chan et al.   NATURE BIOTECHNOLOGY

Small molecule–mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer

(2009) Baozhi Chen et al.   Nature Chemical Biology

Lin28 promotes transformation and is associated with advanced human malignancies

(2009) Srinivas R Viswanathan et al.   NATURE GENETICS

Tcf3 is an integral component of the core regulatory circuitry of embryonic stem cells

(2008) M. F. Cole et al.   GENES & DEVELOPMENT

Lin28 Mediates the Terminal Uridylation of let-7 Precursor MicroRNA

(2008) Inha Heo et al.   MOLECULAR CELL

A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment

(2008) Agnieszka Rybak et al.   NATURE CELL BIOLOGY

Reprogramming of murine and human somatic cells using a single polycistronic vector

(2008) B. W. Carey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing

(2008) M. A. Newman et al.   RNA

Selective Blockade of MicroRNA Processing by Lin28

(2008) S. R. Viswanathan et al.   SCIENCE