Article
Neurosciences
Daniel Yochai Panitz, Aviva Berkovich-Ohana, Avi Mendelsohn
Summary: Evidence suggests a long-axis functional division of the hippocampus, with different regions connected to different brain networks and influenced by age. Aging leads to disruptions in intra-hippocampal signal uniformity and changes in functional connectivity.
Article
Radiology, Nuclear Medicine & Medical Imaging
Florence L. Chiang, Max Feng, Rebecca S. Romero, Larry Price, Crystal G. Franklin, Shengwen Deng, Jodie P. Gray, Fang F. Yu, Bundhit Tantiwongkosi, Susie Y. Huang, Peter T. Fox
Summary: The study defined the atrophy-based functional network model using coordinate-based meta-analysis, revealing the association of functional network disruption in multiple sclerosis and finding a strong positive correlation with clinical disability on resting-state functional MRI scans.
Article
Neuroimaging
Hua Lin, Muwei Li, Yang Zhan, Li Lin, Kun Yang, Shimin Hu, Ying Han
Summary: The study investigated the impact of APOE ε4 on specific white matter functional connectivity in aMCI patients, revealing decreased functional connectivity in specific regions in APOE ε4 carriers, which differed from regions of aMCI-related changes. The findings suggest that APOE ε4 genotype exerts a negative impact on neural activity in both gray and white matter, potentially contributing to functional disconnection and memory decline in aMCI.
BRAIN IMAGING AND BEHAVIOR
(2021)
Article
Neurosciences
S. Duke Han, Debra A. Fleischman, Lei Yu, Victoria Poole, Melissa Lamar, Namhee Kim, Sue E. Leurgans, David A. Bennett, Konstantinos Arfanakis, Lisa L. Barnes
Summary: This study investigated neuroimaging correlates of cognitive decline in older Black adults and found that global cognitive decline was associated with functional connectivity of the hippocampus to the dorsolateral prefrontal cortex. Decline in semantic memory was associated with connectivity of the hippocampus to the precentral gyrus, and decline in perceptual speed was inversely associated with connectivity of the hippocampus to the intracalcarine cortex and the fusiform gyrus.
HUMAN BRAIN MAPPING
(2022)
Article
Neurosciences
Leonie Borne, Ye Tian, Michelle K. Lupton, Johan N. van der Meer, Jayson Jeganathan, Bryan Paton, Nikitas Koussis, Christine C. Guo, Gail A. Robinson, Jurgen Fripp, Andrew Zalesky, Michael Breakspear
Summary: The functional organization of the hippocampus changes smoothly along connectivity gradients and abruptly at inter-areal boundaries, similar to the cortex. This organization allows for flexible integration of hippocampal gradients into cortical networks. By studying fMRI data, researchers found that the functional connectivity gradients of the hippocampus map onto connectivity gradients in the default mode network. The presence of familiar cues accentuates a stepwise transition across the boundary from the anterior to the posterior hippocampus, which is shifted in individuals with mild cognitive impairment or Alzheimer's disease.
Article
Neurosciences
Li-Ying Liu, Xiang Li, Zi-Lei Tian, Qi Zhang, Zhi-Fu Shen, Wei Wei, Xiao-Li Guo, Ling Chen, Meng-Hua Su, Lu Yang, Si-Yi Yu, Jie Yang
Summary: This study aimed to investigate how acupuncture modulates brain activities to achieve therapeutic effects in patients with premenstrual dysphoric disorder (PDM). The results showed that verum acupuncture could effectively modulate frequency-dependent global functional connectivity density (gFCD) by influencing abnormal DLPFC and hippocampus activity, which may enhance the potency of acupuncture in clinical practice.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Neurosciences
Tao Yin, Yuzhu Qu, Yangke Mao, Pan Zhang, Peihong Ma, Zhaoxuan He, Ruirui Sun, Jin Lu, Yuan Chen, Shuai Yin, Qiyong Gong, Yong Tang, Fanrong Liang, Fang Zeng
Summary: The objective of this study was to construct a prediction model based on clinical-neuroimaging signatures to forecast the individual symptom improvement of functional dyspepsia (FD) patients following acupuncture treatment. The model showed an accuracy of 88% in predicting acupuncture responders and an R-2 of 0.453 in forecasting symptom relief. Factors such as higher resting-state functional connectivity and baseline scores contributed significantly to stronger responsiveness to acupuncture therapy.
HUMAN BRAIN MAPPING
(2023)
Article
Neurosciences
Xiang Liu, Liting Chen, Wenfeng Duan, Haijun Li, Linghong Kong, Yongqiang Shu, Panmei Li, Kunyao Li, Wei Xie, Yaping Zeng, Dechang Peng
Summary: This study aimed to investigate the changes in functional connectivity between hippocampal subdivisions and their relationship with neurocognitive function in male patients with untreated severe obstructive sleep apnoea (OSA). The results revealed functional connectivity abnormalities predominantly in the sensorimotor network, fronto-parietal network, and semantic/default mode network, which are closely related to the neurocognitive impairment observed in OSA patients.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Biology
Xenia Grande, Magdalena M. Sauvage, Andreas Becke, Emrah Duzel, David Berron
Summary: Scene and object information are processed and transmitted through specific pathways in the entorhinal-hippocampal circuitry with different selectivity. The findings suggest that these information-specific pathways play a crucial role in the human entorhinal-hippocampal circuitry.
Article
Neurosciences
Sarah Daviddi, Tiziana Pedale, Laura Serra, Simone Macri, Patrizia Campolongo, Valerio Santangelo
Summary: Individuals with Highly Superior Autobiographical Memory (HSAM) show altered hippocampal resting-state functional connectivity, potentially leading to a reduced ability to discern and select salient information and an increased probability of encoding and consolidating sensory information.
Article
Neurosciences
Zhenglong Lin, Gangqiang Hou, Youli Yao, Zhifeng Zhou, Feiqi Zhu, Linjing Liu, Lingwu Zeng, Yatao Yang, Junxian Ma
Summary: The study found that 40-Hz light can significantly alter the activity and functional connectivity of core brain areas related to memory, while 0-Hz light mainly affects brain areas in the prefrontal cortex. The results suggest that the frequency characteristics of light are important in regulating cognitive functions.
FRONTIERS IN HUMAN NEUROSCIENCE
(2021)
Article
Clinical Neurology
Yanzhe Ning, Sisi Zheng, Sitong Feng, Hao Yao, Zhengtian Feng, Xinzi Liu, Linrui Dong, Hongxiao Jia
Summary: Acupuncture has been shown to improve sleep quality and cognitive function in individuals with insufficient sleep. This study found that acupuncture can modulate extensive brain networks and reverse the altered functional connectivity in individuals after acute sleep deprivation.
FRONTIERS IN NEUROLOGY
(2022)
Article
Psychiatry
Ling-ling Wang, Xiaoqi Sun, Chui-De Chiu, Patrick W. L. Leung, Raymond C. K. Chan, Suzanne H. W. So
Summary: The research found impaired cortico-striatal connectivity in individuals with a high level of schizotypy, but improvements over time. The connectivity between the dorsal striatum and the insula may serve as a marker for temporal changes in positive schizotypy.
ASIAN JOURNAL OF PSYCHIATRY
(2021)
Article
Neurosciences
S. Vinci-Booher, T. W. James, K. H. James
Summary: The study found that the contingency between visual and motor experiences during letter production changed the pattern of functional connectivity among neural communities and resulted in better letter recognition performance. This effect was maintained after training but the functional connections observed immediately after training returned to their pre-training baselines after a no-training delay.
Article
Neuroimaging
Ruirui Sun, Zhaoxuan He, Peihong Ma, Shuai Yin, Tao Yin, Xiaoyan Liu, Jin Lu, Yuzhu Qu, Tingting Zhang, Liuyang Huang, Xueling Suo, Du Lei, Qiyong Gong, Fanrong Liang, Fang Zeng
Summary: This study found that deqi has a significant impact on the efficacy of acupuncture for functional dyspepsia, correlating with resting-state functional connectivity of the amygdala subregions.
BRAIN IMAGING AND BEHAVIOR
(2021)