Journal
HEART FAILURE CLINICS
Volume 16, Issue 1, Pages 71-+Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.hfc.2019.08.008
Keywords
Obesity; Heart failure; Obesity paradox; Body composition; Cardiorespiratory fitness
Categories
Funding
- American Heart Association [19CDA34660318]
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Overweight and obesity adversely impact cardiac structure and function, affecting systolic and diastolic ventricular function. Epidemiologic studies have documented an obesity paradox in large heart failure cohorts, where overweight and obese individuals with established heart failure have a better short- and medium-term prognosis compared with leaner patients; this relationship is strongly impacted by level of cardiorespiratory fitness. There are implications for therapies aimed at increasing lean mass as well as weight loss and improvements in quality of diet for the prevention and treatment of heart failure and concomitant obesity to improve cardiorespiratory fitness.
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