A phenotypic screening platform utilising human spermatozoa identifies compounds with contraceptive activity

Reproductive endocrinologists are the gatekeepers for male infertility care in North America: results of a North American survey on the referral patterns and characteristics of men presenting to male infertility specialists for infertility investigations

(2019) Mary K. Samplaski et al.   FERTILITY AND STERILITY

Disulfiram’s anti-cancer activity reflects targeting NPL4, not inhibition of aldehyde dehydrogenase

(2019) Zdenek Skrott et al.   ONCOGENE

Activation of Toll-like receptor 7/8 encoded by the X chromosome alters sperm motility and provides a novel simple technology for sexing sperm

(2019) Takashi Umehara et al.   PLOS BIOLOGY

The demographic impact and development benefits of meeting demand for family planning with modern contraceptive methods

(2018) Daniel Goodkind et al.   Global Health Action

Male hormonal contraceptive — are we there yet?

(2018) Stephanie T. Page et al.   Nature Reviews Endocrinology

The ReFRAME library as a comprehensive drug repurposing library and its application to the treatment of cryptosporidiosis

(2018) Jeff Janes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The diagnosis of male infertility: an analysis of the evidence to support the development of global WHO guidance—challenges and future research opportunities

(2017) Christopher L R Barratt et al.   HUMAN REPRODUCTION UPDATE

Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4

(2017) Zdenek Skrott et al.   NATURE

Opportunities and challenges in phenotypic drug discovery: an industry perspective

(2017) John G. Moffat et al.   NATURE REVIEWS DRUG DISCOVERY

Role of disulfide linkage in action of bis(dialkylaminethiocarbonyl)disulfides as potent double-Edged microbicidal spermicide: Design, synthesis and biology

(2016) Nand Lal et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

The future of computer-aided sperm analysis

(2015) David Mortimer et al.   ASIAN JOURNAL OF ANDROLOGY

‘How to count sperm properly’: checklist for acceptability of studies based on human semen analysis

(2015) Lars Björndahl et al.   HUMAN REPRODUCTION

Clinically relevant enhancement of human sperm motility using compounds with reported phosphodiesterase inhibitor activity

(2014) Steve Tardif et al.   HUMAN REPRODUCTION

Quantifying the chemical beauty of drugs

(2012) G. Richard Bickerton et al.   Nature Chemistry

How were new medicines discovered?

(2011) David C. Swinney et al.   NATURE REVIEWS DRUG DISCOVERY