De novo design of a homo-trimeric amantadine-binding protein

Efficacy and safety of amantadine for the treatment of l-DOPA-induced dyskinesia

(2018) Santiago Perez-Lloret et al.   JOURNAL OF NEURAL TRANSMISSION

Inhibitors of the M2 Proton Channel Engage and Disrupt Transmembrane Networks of Hydrogen-Bonded Waters

(2018) Jessica L. Thomaston et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

De novo design of a fluorescence-activating β-barrel

(2018) Jiayi Dou et al.   NATURE

De novo design of a hyperstable non-natural protein–ligand complex with sub-Å accuracy

(2017) Nicholas F. Polizzi et al.   Nature Chemistry

Sampling and energy evaluation challenges in ligand binding protein design

(2017) Jiayi Dou et al.   PROTEIN SCIENCE

Design of a hyperstable 60-subunit protein icosahedron

(2016) Yang Hsia et al.   NATURE

Computational design of a homotrimeric metalloprotein with a trisbipyridyl core

(2016) Jeremy H. Mills et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity

(2016) S. E. Boyken et al.   SCIENCE

Accurate design of megadalton-scale two-component icosahedral protein complexes

(2016) J. B. Bale et al.   SCIENCE

Two-Dimensional NMR Lineshape Analysis

(2016) Christopher A. Waudby et al.   Scientific Reports

Coupling Protein Side-Chain and Backbone Flexibility Improves the Re-design of Protein-Ligand Specificity

(2015) Noah Ollikainen et al.   PLoS Computational Biology

NMRFAM-SPARKY: enhanced software for biomolecular NMR spectroscopy

(2014) Woonghee Lee et al.   BIOINFORMATICS

The IMAGINE instrument: first neutron protein structure and new capabilities for neutron macromolecular crystallography

(2013) Flora Meilleur et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Computational design of ligand-binding proteins with high affinity and selectivity

(2013) Christine E. Tinberg et al.   NATURE

Manipulating signaling at will: chemically-inducible dimerization (CID) techniques resolve problems in cell biology

(2013) Robert DeRose et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Rapid and orthogonal logic gating with a gibberellin-induced dimerization system

(2012) Takafumi Miyamoto et al.   Nature Chemical Biology

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Molecular Dynamics Simulation Directed Rational Design of Inhibitors Targeting Drug-Resistant Mutants of Influenza A Virus M2

(2011) Jun Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Joint X-ray and neutron refinement withphenix.refine

(2010) Pavel V. Afonine et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Chemically Controlled Protein Assembly: Techniques and Applications

(2010) Adrian Fegan et al.   CHEMICAL REVIEWS