Misfolded proteins bind and activate death receptor 5 to trigger apoptosis during unresolved endoplasmic reticulum stress
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Title
Misfolded proteins bind and activate death receptor 5 to trigger apoptosis during unresolved endoplasmic reticulum stress
Authors
Keywords
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Journal
eLife
Volume 9, Issue -, Pages -
Publisher
eLife Sciences Publications, Ltd
Online
2020-01-06
DOI
10.7554/elife.52291
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- (2019) Liqiang Pan et al. CELL
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- Structural principles of tumor necrosis factor superfamily signaling
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- Structural principles of tumor necrosis factor superfamily signaling
- (2018) Éva S. Vanamee et al. Science Signaling
- Coordination between Two Branches of the Unfolded Protein Response Determines Apoptotic Cell Fate
- (2018) Tsun-Kai Chang et al. MOLECULAR CELL
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- (2017) Nagamani Vunnam et al. JOURNAL OF MOLECULAR BIOLOGY
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- (2017) Raffaella Iurlaro et al. MOLECULAR AND CELLULAR BIOLOGY
- Neurodegeneration-associated mutant TREM2 proteins abortively cycle between the ER and ER–Golgi intermediate compartment
- (2017) Daniel W. Sirkis et al. MOLECULAR BIOLOGY OF THE CELL
- Secretory stressors induce intracellular death receptor accumulation to control apoptosis
- (2017) Bram J van Raam et al. Cell Death & Disease
- An unfolded protein-induced conformational switch activates mammalian IRE1
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- (2016) Cherie M. Southwood et al. JOURNAL OF NEUROSCIENCE
- TRAIL receptor gene editing unveils TRAIL-R1 as a master player of apoptosis induced by TRAIL and ER stress
- (2016) Florent Dufour et al. Oncotarget
- Targeting the extrinsic apoptotic pathway in cancer: lessons learned and future directions
- (2015) Avi Ashkenazi JOURNAL OF CLINICAL INVESTIGATION
- PAQR3 modulates cholesterol homeostasis by anchoring Scap/SREBP complex to the Golgi apparatus
- (2015) Daqian Xu et al. Nature Communications
- ER Stress-Induced Clearance of Misfolded GPI-Anchored Proteins via the Secretory Pathway
- (2014) Prasanna Satpute-Krishnan et al. CELL
- Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis
- (2014) M. Lu et al. SCIENCE
- Isolation, characterisation and reconstitution of cell death signalling complexes
- (2013) Michelle A. Hughes et al. METHODS
- ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death
- (2013) Jaeseok Han et al. NATURE CELL BIOLOGY
- Endoplasmic Reticulum Stress Sensing in the Unfolded Protein Response
- (2013) B. M. Gardner et al. Cold Spring Harbor Perspectives in Biology
- Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) Induces Death Receptor 5 Networks That Are Highly Organized
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- A Death Effector Domain Chain DISC Model Reveals a Crucial Role for Caspase-8 Chain Assembly in Mediating Apoptotic Cell Death
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- (2011) Sophie C. Cazanave et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress
- (2011) Ira Tabas et al. NATURE CELL BIOLOGY
- The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation
- (2011) P. Walter et al. SCIENCE
- Unfolded Proteins Are Ire1-Activating Ligands That Directly Induce the Unfolded Protein Response
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- Multivalent DR5 Peptides Activate the TRAIL Death Pathway and Exert Tumoricidal Activity
- (2010) V. Pavet et al. CANCER RESEARCH
- Cullin3-Based Polyubiquitination and p62-Dependent Aggregation of Caspase-8 Mediate Extrinsic Apoptosis Signaling
- (2009) Zhaoyu Jin et al. CELL
- Ablation of the UPR-Mediator CHOP Restores Motor Function and Reduces Demyelination in Charcot-Marie-Tooth 1B Mice
- (2008) Maria Pennuto et al. NEURON
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