SynToxProfiler: An interactive analysis of drug combination synergy, toxicity and efficacy

Ibrutinib and Venetoclax for First-Line Treatment of CLL

(2019) Nitin Jain et al.   NEW ENGLAND JOURNAL OF MEDICINE

Patient-Customized Drug Combination Prediction and Testing for T-cell Prolymphocytic Leukemia Patients

(2018) Liye He et al.   CANCER RESEARCH

Identification of Combinations of Approved Drugs With Synergistic Activity Against Ebola Virus in Cell Cultures

(2018) Julie Dyall et al.   JOURNAL OF INFECTIOUS DISEASES

Cytarabine and daunorubicin for the treatment of acute myeloid leukemia

(2017) Tracy Murphy et al.   EXPERT OPINION ON PHARMACOTHERAPY

Discovery of novel drug sensitivities in T-PLL by high-throughput ex vivo drug testing and mutation profiling

(2017) E I Andersson et al.   LEUKEMIA

Combenefit: an interactive platform for the analysis and visualization of drug combinations

(2016) Giovanni Y. Di Veroli et al.   BIOINFORMATICS

Identification of selective cytotoxic and synthetic lethal drug responses in triple negative breast cancer cells

(2016) Prson Gautam et al.   Molecular Cancer

Combine and conquer: challenges for targeted therapy combinations in early phase trials

(2016) Juanita S. Lopez et al.   Nature Reviews Clinical Oncology

Failure of Investigational Drugs in Late-Stage Clinical Development and Publication of Trial Results

(2016) Thomas J. Hwang et al.   JAMA Internal Medicine

A screen of approved drugs and molecular probes identifies therapeutics with anti–Ebola virus activity

(2015) Lisa M. Johansen et al.   Science Translational Medicine

Searching for Drug Synergy in Complex Dose–Response Landscapes Using an Interaction Potency Model

(2015) Bhagwan Yadav et al.   Computational and Structural Biotechnology Journal

A Correlation Between the In Vitro Drug Toxicity of Drugs to Cell Lines That Express Human P450s and Their Propensity to Cause Liver Injury in Humans

(2013) Frida Gustafsson et al.   TOXICOLOGICAL SCIENCES

Synergistic Drug Combinations for Tuberculosis Therapy Identified by a Novel High-Throughput Screen

(2011) Santiago Ramón-García et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Phase II failures: 2008–2010

(2011) John Arrowsmith   NATURE REVIEWS DRUG DISCOVERY

Colchicine poisoning: the dark side of an ancient drug

(2010) Yaron Finkelstein et al.   CLINICAL TOXICOLOGY