Host factor prioritization for pan-viral genetic perturbation screens using random intercept models and network propagation

Oncogenic role of PLCG1 in progression of hepatocellular carcinoma

(2019) Wenqing Tang et al.   HEPATOLOGY RESEARCH

netprioR: a probabilistic model for integrative hit prioritisation of genetic screens

(2019) Fabian Schmich et al.   Statistical Applications in Genetics and Molecular Biology

Reciprocal Effects of Fibroblast Growth Factor Receptor Signaling on Dengue Virus Replication and Virion Production

(2019) Mirko Cortese et al.   Cell Reports

Network-based integration of multi-omics data for prioritizing cancer genes

(2018) Christos Dimitrakopoulos et al.   BIOINFORMATICS

Proteasome inhibitors in cancer therapy

(2017) Elisabet E. Manasanch et al.   Nature Reviews Clinical Oncology

Network propagation: a universal amplifier of genetic associations

(2017) Lenore Cowen et al.   NATURE REVIEWS GENETICS

A CRISPR screen defines a signal peptide processing pathway required by flaviviruses

(2016) Rong Zhang et al.   NATURE

Genetic dissection of Flaviviridae host factors through genome-scale CRISPR screens

(2016) Caleb D. Marceau et al.   NATURE

A human genome-wide loss-of-function screen identifies effective chikungunya antiviral drugs

(2016) Alexander Karlas et al.   Nature Communications

Identification of Zika Virus and Dengue Virus Dependency Factors using Functional Genomics

(2016) George Savidis et al.   Cell Reports

Building Viral Replication Organelles: Close Encounters of the Membrane Types

(2016) Peter D. Nagy et al.   PLoS Pathogens

An integrative approach for a network based meta-analysis of viral RNAi screens

(2015) Sandeep S Amberkar et al.   Algorithms for Molecular Biology

Characterizing the effect of Bortezomib on Rift Valley Fever Virus multiplication

(2015) Forrest Keck et al.   ANTIVIRAL RESEARCH

Phosphatidylinositol 4,5-Bisphosphate Is an HCV NS5A Ligand and Mediates Replication of the Viral Genome

(2015) Nam-Joon Cho et al.   GASTROENTEROLOGY

Fitting Linear Mixed-Effects Models Usinglme4

(2015) Douglas Bates et al.   Journal of Statistical Software

A Kinome-Wide Small Interfering RNA Screen Identifies Proviral and Antiviral Host Factors in Severe Acute Respiratory Syndrome Coronavirus Replication, Including Double-Stranded RNA-Activated Protein Kinase and Early Secretory Pathway Proteins

(2015) Adriaan H. de Wilde et al.   JOURNAL OF VIROLOGY

Identification of HNRNPK as Regulator of Hepatitis C Virus Particle Production

(2015) Marion Poenisch et al.   PLoS Pathogens

Simultaneous analysis of large-scale RNAi screens for pathogen entry

(2015) Pauli Rämö et al.   BMC GENOMICS

Kinome siRNA screen identifies novel cell-type specific dengue host target genes

(2014) Yong-Jun Kwon et al.   ANTIVIRAL RESEARCH

Single-cell and multivariate approaches in genetic perturbation screens

(2014) Prisca Liberali et al.   NATURE REVIEWS GENETICS

A Novel, Broad-Spectrum Inhibitor of Enterovirus Replication That Targets Host Cell Factor Phosphatidylinositol 4-Kinase IIIβ

(2013) Hilde M. van der Schaar et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Mining Quasi-Bicliques from HIV-1-Human Protein Interaction Network: A Multiobjective Biclustering Approach

(2012) Ujjwal Maulik et al.   IEEE-ACM Transactions on Computational Biology and Bioinformatics

Recruitment and Activation of a Lipid Kinase by Hepatitis C Virus NS5A Is Essential for Integrity of the Membranous Replication Compartment

(2011) Simon Reiss et al.   Cell Host & Microbe

Comparative RNAi Screening Reveals Host Factors Involved in Enterovirus Infection of Polarized Endothelial Monolayers

(2011) Carolyn B. Coyne et al.   Cell Host & Microbe

Origins of regulated cell-to-cell variability

(2011) Berend Snijder et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Hepatitis c virus and host cell lipids: An intimate connection

(2011) Gualtiero Alvisi et al.   RNA Biology

A human functional protein interaction network and its application to cancer data analysis

(2010) Guanming Wu et al.   GENOME BIOLOGY

A network-based integrative approach to prioritize reliable hits from multiple genome-wide RNAi screens in Drosophila

(2009) Li Wang et al.   BMC GENOMICS

Population context determines cell-to-cell variability in endocytosis and virus infection

(2009) Berend Snijder et al.   NATURE

Viral avoidance and exploitation of the ubiquitin system

(2009) Felix Randow et al.   NATURE CELL BIOLOGY

RNAi screening: tips and techniques

(2009) Sonia Sharma et al.   NATURE IMMUNOLOGY

Statistical methods for analysis of high-throughput RNA interference screens

(2009) Amanda Birmingham et al.   NATURE METHODS

The art and design of genetic screens: RNA interference

(2008) Michael Boutros et al.   NATURE REVIEWS GENETICS