Intestinal peroxisomal fatty acid β-oxidation regulates neural serotonin signaling through a feedback mechanism

Data processing, multi-omic pathway mapping, and metabolite activity analysis using XCMS Online

(2018) Erica M Forsberg et al.   Nature Protocols

The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2018 update

(2018) Enis Afgan et al.   NUCLEIC ACIDS RESEARCH

Direct neurotransmitter activation of voltage-gated potassium channels

(2018) Rían W. Manville et al.   Nature Communications

Energy Scarcity Promotes a Brain-wide Sleep State Modulated by Insulin Signaling in C. elegans

(2018) Susanne Skora et al.   Cell Reports

Regulation of reproduction and longevity by nutrient-sensing pathways

(2017) Nicole M. Templeman et al.   JOURNAL OF CELL BIOLOGY

Food responsiveness regulates episodic behavioral states in Caenorhabditis elegans

(2017) Richard J. McCloskey et al.   JOURNAL OF NEUROPHYSIOLOGY

A tachykinin-like neuroendocrine signalling axis couples central serotonin action and nutrient sensing with peripheral lipid metabolism

(2017) Lavinia Palamiuc et al.   Nature Communications

Multi-omics Analyses of Starvation Responses Reveal a Central Role for Lipoprotein Metabolism in Acute Starvation Survival in C. elegans

(2017) Eva Bang Harvald et al.   Cell Systems

Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking

(2016) Mingxun Wang et al.   NATURE BIOTECHNOLOGY

Structural characterization of acyl-CoA oxidases reveals a direct link between pheromone biosynthesis and metabolic state inCaenorhabditis elegans

(2016) Xinxing Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

C. elegans Body Cavity Neurons Are Homeostatic Sensors that Integrate Fluctuations in Oxygen Availability and Internal Nutrient Reserves

(2016) Emily Witham et al.   Cell Reports

Nutrients, satiety, and control of energy intake

(2015) Angelo Tremblay et al.   Applied Physiology Nutrition and Metabolism

Kynurenic Acid Is a Nutritional Cue that Enables Behavioral Plasticity

(2015) George A. Lemieux et al.   CELL

Mass spectral similarity for untargeted metabolomics data analysis of complex mixtures

(2015) Neha Garg et al.   INTERNATIONAL JOURNAL OF MASS SPECTROMETRY

Nutrient-sensing mechanisms and pathways

(2015) Alejo Efeyan et al.   NATURE

Long-chain acyl-CoA esters in metabolism and signaling: Role of acyl-CoA binding proteins

(2015) Ditte Neess et al.   PROGRESS IN LIPID RESEARCH

Acyl-CoA Metabolism and Partitioning

(2014) Trisha J. Grevengoed et al.   Annual Review of Nutrition

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Loss of a Neural AMP-Activated Kinase Mimics the Effects of Elevated Serotonin on Fat, Movement, and Hormonal Secretions

(2014) Katherine A. Cunningham et al.   PLoS Genetics

Metabolic functions of peroxisomes in health and disease

(2013) Ronald J.A. Wanders   BIOCHIMIE

An Integrated Serotonin and Octopamine Neuronal Circuit Directs the Release of an Endocrine Signal to Control C. elegans Body Fat

(2013) Tallie Noble et al.   Cell Metabolism

Succinylated Octopamine Ascarosides and a New Pathway of Biogenic Amine Metabolism inCaenorhabditis elegans

(2013) Alexander B. Artyukhin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Flavonoid regulation of EAG1 channels

(2013) Anne E. Carlson et al.   JOURNAL OF GENERAL PHYSIOLOGY

A Neuronal Signaling Pathway of CaMKII and Gq  Regulates Experience-Dependent Transcription of tph-1

(2013) Y. Qin et al.   JOURNAL OF NEUROSCIENCE

Fatty Acid Modulation of the Endocannabinoid System and the Effect on Food Intake and Metabolism

(2013) Shaan S. Naughton et al.   International Journal of Endocrinology

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

2D NMR-Based Metabolomics Uncovers Interactions between Conserved Biochemical Pathways in the Model Organism Caenorhabditis elegans

(2012) Yevgeniy Izrayelit et al.   ACS Chemical Biology

XCMS Online: A Web-Based Platform to Process Untargeted Metabolomic Data

(2012) Ralf Tautenhahn et al.   ANALYTICAL CHEMISTRY

AMP-Activated Kinase Links Serotonergic Signaling to Glutamate Release for Regulation of Feeding Behavior in C. elegans

(2012) Katherine A. Cunningham et al.   Cell Metabolism

Quantitative screening of genes regulating tryptophan hydroxylase transcription in Caenorhabditis elegans using microfluidics and an adaptive algorithm

(2012) Hyewon Lee et al.   Integrative Biology

Serotonin Activates Overall Feeding by Activating Two Separate Neural Pathways in Caenorhabditis elegans

(2012) B.-m. Song et al.   JOURNAL OF NEUROSCIENCE

Optimization of a GCaMP Calcium Indicator for Neural Activity Imaging

(2012) J. Akerboom et al.   JOURNAL OF NEUROSCIENCE

Comparative Metabolomics Reveals Biogenesis of Ascarosides, a Modular Library of Small-Molecule Signals in C. elegans

(2012) Stephan H. von Reuss et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Central nervous system control of metabolism

(2012) Martin G. Myers et al.   NATURE

Tonic signaling from O2 sensors sets neural circuit activity and behavioral state

(2012) Karl Emanuel Busch et al.   NATURE NEUROSCIENCE

AMPK: a nutrient and energy sensor that maintains energy homeostasis

(2012) D. Grahame Hardie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The ketogenic diet: metabolic influences on brain excitability and epilepsy

(2012) Andrew Lutas et al.   TRENDS IN NEUROSCIENCES

A Modular Library of Small Molecule Signals Regulates Social Behaviors in Caenorhabditis elegans

(2012) Jagan Srinivasan et al.   PLOS BIOLOGY

N-acylethanolamine signalling mediates the effect of diet on lifespan in Caenorhabditis elegans

(2011) Mark Lucanic et al.   NATURE

Mutations in a Guanylate Cyclase GCY-35/GCY-36 Modify Bardet-Biedl Syndrome–Associated Phenotypes in Caenorhabditis elegans

(2011) Calvin A. Mok et al.   PLoS Genetics

The Kennedy pathway-De novo synthesis of phosphatidylethanolamine and phosphatidylcholine

(2010) Federica Gibellini et al.   IUBMB LIFE

Contribution of the PeroxisomalacoxGene to the Dynamic Balance of Daumone Production inCaenorhabditis elegans

(2010) Hyoe-Jin Joo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The effects of transient starvation persist through direct interactions between CaMKII and ether-a-go-go K+ channels in C. elegans males

(2010) B. LeBoeuf et al.   NEUROSCIENCE

Technical Advance: A novel technique for the sensitive quantification of acyl CoA esters from plant tissues

(2010) Tony R. Larson et al.   PLANT JOURNAL

Identifying Regulators for EAG1 Channels with a Novel Electrophysiology and Tryptophan Fluorescence Based Screen

(2010) Tinatin I. Brelidze et al.   PLoS One

Hypothalamic nutrient sensing in the control of energy homeostasis

(2009) Clémence Blouet et al.   BEHAVIOURAL BRAIN RESEARCH

Endocannabinoid signals in the control of emotion

(2009) Beat Lutz   CURRENT OPINION IN PHARMACOLOGY

A hub-and-spoke circuit drives pheromone attraction and social behaviour in C. elegans

(2009) Evan Z. Macosko et al.   NATURE

Neurons Detect Increases and Decreases in Oxygen Levels Using Distinct Guanylate Cyclases

(2009) Manuel Zimmer et al.   NEURON

Biosynthesis of theCaenorhabditis elegansdauer pheromone

(2009) Rebecca A. Butcher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Serotonin Regulates C. elegans Fat and Feeding through Independent Molecular Mechanisms

(2008) Supriya Srinivasan et al.   Cell Metabolism

Insulin, cGMP, and TGF-β Signals Regulate Food Intake and Quiescence in C. elegans: A Model for Satiety

(2008) Young-jai You et al.   Cell Metabolism