Article
Medicine, General & Internal
Riccardo Polosa, Jaymin B. Morjaria, Umberto Prosperini, Barbara Busa, Alfio Pennisi, Gualberto Gussoni, Sonja Rust, Marilena Maglia, Pasquale Caponnetto
Summary: This study demonstrates that COPD patients who switch to heated tobacco products experience significant improvements in respiratory symptoms, exercise tolerance, quality of life, and rate of disease exacerbations over a 3-year period, while no significant changes were observed in patients who continued smoking.
INTERNAL AND EMERGENCY MEDICINE
(2021)
Article
Substance Abuse
Charlotte N. E. Tompkins, Annabel Burnley, Ann McNeill, Sara C. Hitchman
Summary: The study identified six main factors influencing initiation and use of IQOS among smokers and ex-smokers, including health, financial, physical, practical, psychological, and social factors. The findings suggest that factors such as packaging, labeling, risk communication, price, and smoke-free policies play a role in influencing the decision to use IQOS.
Review
Substance Abuse
Sophie Braznell, Amber van den Akker, Chris Metcalfe, Gemma M. J. Taylor, Jamie Hartmann-Boyce
Summary: This study critically evaluates the methodological characteristics and quality of interventional clinical trials investigating the effects of heated tobacco products (HTPs). The findings suggest that these trials have poor conduct and reporting and are limited to investigating short-term exposure effects. This raises concerns about their reliability as a basis for tobacco control policy decisions.
Review
Substance Abuse
Malak El-Kaassamani, Miaoshan Yen, Soha Talih, Ahmad El-Hellani
Summary: This article highlights the general features of IQOS literature, focusing on the chemical analysis of IQOS emissions. The study compares data from different sources and reveals the agreement and disagreement between PMI-sponsored and independent research. The analysis shows consistent nicotine yield from IQOS under the same puffing conditions and significantly reduced levels of some emissions compared to combustible cigarettes. However, there are significant increases in other emissions from IQOS, as indicated by independent studies and examination of PMI's data.
Article
Substance Abuse
Jungmi Jun, Sei-Hill Kim, James Thrasher, Yoo Jin Cho, Yu-Jin Heo
Summary: The news coverage of heated tobacco products (HTPs) regulation in South Korea focused mainly on taxation (55.2%) and warning labels (25.7%). While attitudes towards taxation were evenly split between pro-regulation (2.5%) and anti-regulation (2.2%), other restrictions such as warning labels (pro=9.5% vs anti=1.4%), marketing restrictions (pro=6.9% vs anti=0%), and smoke-free policies for cigarettes (pro=8.7% vs anti=0%) were more likely to be portrayed in a positive light. The government (59%) was cited most frequently as a news source, followed by the tobacco industry (39.4%), with a low presence of tobacco control advocates (4.9%). There was no significant difference in the prevalence of news stories mentioning reduced harm (31.7%) and equal or more harm (33.6%) of HTPs compared with conventional cigarettes.
Article
Substance Abuse
Lorien C. Abroms, Chritina N. Wysota, Sararat Tosakoon, Amal Khayat, Zongshuan Duan, Yael Bar-Zeev, Carla J. Berg, Hagai Levine
Summary: This study examined Philip Morris International's global social media marketing of its leading heated tobacco product IQOS. The study found that the company used social media to engage consumers with advertising, event promotions, product use instructions, and price promotions. The findings highlight the need for monitoring and tobacco control regulatory efforts in the digital arena.
Article
Public, Environmental & Occupational Health
Suzana AlMoosawi, Martha Bajec, Nelly Mainy, Gerd Kallischnigg, Bertram Zwisele, Karina Fischer, Pierpaolo Magnani, Steve Roulet
Summary: This study assessed the temporal trends in the health risk perception of IQOS relative to cigarettes among current IQOS users. The results showed that the relative risk perception of IQOS decreased over time.
SSM-POPULATION HEALTH
(2022)
Review
Environmental Sciences
Swapna Upadhyay, Mizanur Rahman, Gunnar Johanson, Lena Palmberg, Koustav Ganguly
Summary: Heated tobacco products (HTPs) allow users to inhale nicotine by heating reconstituted tobacco. The composition of HTP aerosol varies according to the added flavoring agents and contains more harmful and potentially harmful constituents compared to cigarette smoke. The risks of HTP use, especially the long-term effects, are still unknown.
Article
Substance Abuse
Xiaoyu Zhang, Yuying Sun, Yee Tak Derek Cheung, Man Ping Wang, Yongda Socrates Wu, Kin Yeung Chak, Jianjiu Chen, Lok Tung Leung, Tai Hing Lam, Sai Yin Ho
Summary: This study found that users of heated tobacco products had lower levels of exhaled CO and similar levels of saliva cotinine compared to conventional cigarette smokers.
Review
Biochemistry & Molecular Biology
Rosalia Emma, Massimo Caruso, Davide Campagna, Roberta Pulvirenti, Giovanni Li Volti
Summary: Cells constantly produce oxidizing species through their metabolic activity, which is countered by the production of antioxidant species. Smoking is a major exogenous source of these species. Next-generation products like electronic cigarettes and tobacco heating products are proposed as alternatives to reduce the harmful effects of smoking. Tobacco smoke has been established to have significant impact on oxidative stress signaling, while further research is needed to understand the long-term oxidative effects of these alternative products.
Article
Environmental Sciences
Teemu Karkela, Unto Tapper, Tuula Kajolinna
Summary: The study compared the smoke from a research cigarette with the aerosol generated by IQOS, finding that IQOS aerosol emissions were significantly lower than cigarette smoke under the same puffing regimen. Despite similar maximum nicotine concentrations within a puff for both 3R4F smoke and IQOS aerosol, the average concentration was lower for IQOS aerosol. Additionally, water constituted a significant portion of particulate matter in both products, with higher levels in the IQOS aerosol.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Public, Environmental & Occupational Health
Pasquale Caponnetto, Davide Campagna, Marilena Maglia, Francesca Benfatto, Rosalia Emma, Massimo Caruso, Grazia Caci, Barbara Busa, Alfio Pennisi, Maurizio Ceracchi, Marcello Migliore, Maria Signorelli
Summary: This study compared the effectiveness of heated tobacco products (HTPs) and electronic cigarettes (ECs) for smokers who do not intend to quit. The results showed that both HTPs and ECs can effectively reduce cigarette consumption, and the user experience and risk perception are similar between the two.
JMIR PUBLIC HEALTH AND SURVEILLANCE
(2023)
Article
Substance Abuse
Monica Nunes-Rubinstein, Teresa Leao
Summary: This study analyzed three policy discussions on the commercialization and marketing of e-cigarettes and HTPs in order to identify proponents and opponents, examine the arguments used by both sides, and compare how these arguments have changed over time. The findings indicate that tobacco companies mainly argue for the harm reduction potential of e-cigarettes and HTPs compared to conventional tobacco. Unions supporting the commercialization also argue that lifting the ban would prevent smuggling and ensure product quality. On the other hand, universities, medical organizations, and anti-tobacco institutions argue that these devices may pose health risks, including the risk of inducing cigarette smoking. In addition, the study found that the focus of the arguments shifted from "health" in 2009 to economic and moral/ethical themes in 2018 and 2019.
Article
Substance Abuse
Ollie Ganz, Andrew A. Strasser, Daniel P. Giovenco, Janet Audrain-McGovern, Joseph N. Cappella, Zeinab Safi, Andy S. L. Tan, Eugene M. Talbot, Cristine D. Delnevo
Summary: IQOS, a heated tobacco product, was authorized as a modified risk tobacco product (MRTP) in July 2020. Despite being removed from the US market in 2021, surveillance of IQOS marketing is crucial for future MRTP regulation and policy. This study analyzed IQOS ads in print magazines before and after MRTP authorization, revealing an increase in ad expenditures and a focus on Marlboro HeatSticks and female-targeted magazines after MRTP authorization. Monitoring IQOS advertisement content, placement, and expenditures will be important if it returns to the US market.
Article
Substance Abuse
Stephanie Edwards, Lisa Fitzgerald, Allyson Mutch, Judith A. Dean, Pauline Ford, Chris Howard, Peter Watts, Coral Gartner
Summary: This study examined the role of smoking among PLHIV, their views on traditional and novel nicotine products, and categorized participants into groups based on smoking commitment and interest in quitting. While nicotine replacement therapy was criticized for side effects and seen as a short-term aid, nicotine vaping products were debated and products resembling cigarettes were considered suitable long-term substitutes, particularly for PLHIV who are ambivalent about smoking.
INTERNATIONAL JOURNAL OF DRUG POLICY
(2021)
Letter
Dermatology
Katarzyna Kunkiel, Agata Natkanska, Monika Nedzi, Anna Zawadzka-Krajewska, Wojciech Feleszko
JOURNAL OF DERMATOLOGICAL TREATMENT
(2022)
Letter
Allergy
Dominika Ambrozej, Katarzyna Kunkiel, Karolina Dumycz, Wojciech Feleszko
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
(2021)
Review
Allergy
Marek Ruszczynski, Dominika Ambrozej, Aleksander Adamiec, Klaudia Ryczaj, Varpu Elenius, Ozlem Cavkaytar, Paraskevi Maggina, Heidi Makrinioti, Nikolaos Papadopoulos, Gunilla Hedlin, Jon R. Konradsen, Bianca Schaub, Hermelijn H. Smits, Tuomas Jartti, Wojciech Feleszko
Summary: The study found variations in the quality of guidelines for asthma management in children, and a significant gap in reliable recommendations for the management and treatment of non-asthmatic preschool wheeze.
PEDIATRIC ALLERGY AND IMMUNOLOGY
(2021)
Review
Allergy
Varpu Elenius, Bo Chawes, Pekka L. Malmberg, Aleksander Adamiec, Marek Ruszczynski, Wojciech Feleszko, Tuomas Jartti
Summary: The review suggests that FEV1 measurement using spirometry is useful, and for those unable to perform spirometry, whole-body plethysmography and IOS may be helpful. Adding bronchial reversibility to beta2-agonist and hyperresponsiveness tests could improve the sensitivity of the tests. A lack of large randomized controlled trials makes it challenging to establish monitoring guidelines for asthma in preschool children.
PEDIATRIC ALLERGY AND IMMUNOLOGY
(2021)
Article
Immunology
Wojciech Feleszko, Piotr Lewulis, Adam Czarnecki, Pawel Waszkiewicz
Summary: Research indicates varying levels of acceptance towards the COVID-19 vaccine globally, with some countries exhibiting high levels of vaccine hesitancy. To achieve a 67% herd immunity, early implementation of mandatory preventive vaccination programs, coupled with legislative support and coordinated education efforts, are crucial.
Article
Allergy
Anna D. J. Korath, Jozef Janda, Eva Untersmayr, Milena Sokolowska, Wojciech Feleszko, Ioana Agache, Ahmed Adel Seida, Katrin Hartmann, Erika Jensen-Jarolim, Isabella Pali-Schoell
Summary: As indicated by the study, similar pandemics may occur more frequently in the future due to factors such as climate change, consumption of exotic foods and drinks, global travel, increasing world population, decreasing production space, declining wildlife and free-ranging animal habitats, as well as changed lifestyles. Both society and health authorities need to be alert and well-prepared for similar future situations, with research focusing on prevention and rapid development of treatment options (medications, vaccines).
Article
Microbiology
Magdalena Grochowska, Dominika Ambrozej, Aneta Wachnik, Urszula Demkow, Edyta Podsiadly, Wojciech Feleszko
Summary: The measures implemented during the COVID-19 pandemic effectively reduced the incidence of lower respiratory tract infections and various viral infections, but had little impact on gastrointestinal bacterial infections. However, an unexpected increase in RSV-positive cases was observed in August 2021.
Review
Allergy
Heidi Makrinioti, Kohei Hasegawa, John Lakoumentas, Paraskevi Xepapadaki, Maria Tsolia, Jose A. Castro-Rodriguez, Wojciech Feleszko, Tuomas Jartti, Sebastian L. Johnston, Andrew Bush, Vasiliki Papaevangelou, Carlos A. Camargo, Nikolaos G. Papadopoulos
Summary: This study compares the associations of RSV-induced bronchiolitis and RV-induced bronchiolitis with the development of preschool wheeze and childhood asthma through a meta-analysis. The results show that the RV-bronchiolitis group is more likely to develop recurrent wheeze and asthma. This study is clinically significant for understanding the relationship between viruses and asthma.
PEDIATRIC ALLERGY AND IMMUNOLOGY
(2022)
Article
Medicine, General & Internal
Agnieszka Strzelak, Anna Komorowska-Piotrowska, Katarzyna Krenke, Wioletta Zagorska, Witold Bartosiewicz, Wojciech Feleszko, Marek Kulus
Summary: This study found that IP-10 can be detected in unstimulated BALF in children with respiratory diseases, with higher concentrations compared to plasma, but it does not correlate with age and cannot be used to differentiate MTBI from other respiratory diseases.
Letter
Allergy
Klaudia Ryczaj, Karolina Dumycz, Radoslaw Spiewak, Wojciech Feleszko
Summary: This study investigated the presence of haptens in moisturizers used in preventative therapy for atopic dermatitis and food allergies. The majority of moisturizers contained at least one potentially harmful hapten. Due to the heterogeneity of preparations used, quantitative data synthesis on the prevention of food allergies and atopic dermatitis was not possible. The study highlights the importance of careful selection of moisturizers, particularly for young children, to avoid potential harm.
CLINICAL AND TRANSLATIONAL ALLERGY
(2022)
Article
Immunology
Pawel Waszkiewicz, Piotr Lewulis, Michal Gorski, Adam Czarnecki, Wojciech Feleszko
Summary: This paper presents a longitudinal cohort survey on the public acceptability of COVID-19 vaccination and real vaccination levels. It found that a significant portion of individuals who initially expressed reluctance or hesitation towards the vaccine eventually got vaccinated or have plans to do so. The main reasons for their change in attitude included concern for their health and safety, as well as the desire to travel. The main factors contributing to increased vaccination acceptance were focused on personal safety and freedom from restrictions.
Letter
Allergy
Marco Caminati, Wojciech Feleszko, Moise Michel, Isabella Annesi-Maesano, Joana Vitte
Letter
Allergy
Karolina Dumycz, Katarzyna Kunkiel, Anna Stelmaszczyk-Emmel, Pawel Jozefczuk, Aleksander Adamiec, Marek Kulus, Wojciech Feleszko
CLINICAL AND EXPERIMENTAL ALLERGY
(2023)
Article
Pediatrics
Katarzyna Ostrzyzek-Przezdziecka, Mariusz Panczyk, Michal Bronikowski, Jakub S. Gasior, Wojciech Feleszko
Summary: The study found that low levels of physical activity in preschoolers can increase the risk of upper respiratory tract infections (URTIs). Parents should encourage their children to engage in physical activity to prevent URTIs.
PEDIATRIC RESEARCH
(2023)
Letter
Allergy
Klaudia Ryczaj, Marek Kulus, Wojciech Feleszko
