An unsupervised learning approach to identify novel signatures of health and disease from multimodal data

Identification of Misclassified ClinVar Variants via Disease Population Prevalence

(2018) Naisha Shah et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Are your covariates under control? How normalization can re-introduce covariate effects

(2018) Oliver Pain et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

National Health Care Spending In 2016: Spending And Enrollment Growth Slow After Initial Coverage Expansions

(2018) Micah Hartman et al.   HEALTH AFFAIRS

The State of US Health, 1990-2016

(2018) et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Multi‐Omics Factor Analysis—a framework for unsupervised integration of multi‐omics data sets

(2018) Ricard Argelaguet et al.   Molecular Systems Biology

The personal and clinical utility of polygenic risk scores

(2018) Ali Torkamani et al.   NATURE REVIEWS GENETICS

Precision medicine screening using whole-genome sequencing and advanced imaging to identify disease risk in adults

(2018) Bradley A. Perkins et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A wellness study of 108 individuals using personal, dense, dynamic data clouds

(2017) Nathan D Price et al.   NATURE BIOTECHNOLOGY

Fast and accurate HLA typing from short-read next-generation sequence data with xHLA

(2017) Chao Xie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

p-Cresyl Sulfate

(2017) Tessa Gryp et al.   Toxins

Hippurate as a metabolomic marker of gut microbiome diversity: Modulation by diet and relationship to metabolic syndrome

(2017) Tess Pallister et al.   Scientific Reports

Deep sequencing of 10,000 human genomes

(2016) Amalio Telenti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A robust ambient temperature collection and stabilization strategy: Enabling worldwide functional studies of the human microbiome

(2016) Ericka L. Anderson et al.   Scientific Reports

Colonic transit time is related to bacterial metabolism and mucosal turnover in the gut

(2016) Henrik M. Roager et al.   Nature Microbiology

Characterization of the Gut Microbial Community of Obese Patients Following a Weight-Loss Intervention Using Whole Metagenome Shotgun Sequencing

(2016) Sandrine Louis et al.   PLoS One

Sodium butyrate epigenetically modulates high-fat diet-induced skeletal muscle mitochondrial adaptation, obesity and insulin resistance through nucleosome positioning

(2015) Tara M Henagan et al.   BRITISH JOURNAL OF PHARMACOLOGY

Dietary protein-fiber ratio associates with circulating levels of indoxyl sulfate and p-cresyl sulfate in chronic kidney disease patients

(2015) M. Rossi et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Production of butyrate from lysine and the Amadori product fructoselysine by a human gut commensal

(2015) Thi Phuong Nam Bui et al.   Nature Communications

Insights into the Role of Erysipelotrichaceae in the Human Host

(2015) Nadeem O. Kaakoush   Frontiers in Cellular and Infection Microbiology

Meta-Analysis of the Associations of p-Cresyl Sulfate (PCS) and Indoxyl Sulfate (IS) with Cardiovascular Events and All-Cause Mortality in Patients with Chronic Renal Failure

(2015) Cheng-Jui Lin et al.   PLoS One

Heritability and Clinical Determinants of Serum Indoxyl Sulfate and p-Cresyl Sulfate, Candidate Biomarkers of the Human Microbiome Enterotype

(2014) Liesbeth Viaene et al.   PLoS One

Discoidal HDL and apoA-I-derived peptides improve glucose uptake in skeletal muscle

(2013) Jonathan Dalla-Riva et al.   JOURNAL OF LIPID RESEARCH

Major phenylpropanoid-derived metabolites in the human gut can arise from microbial fermentation of protein

(2013) Wendy R. Russell et al.   MOLECULAR NUTRITION & FOOD RESEARCH

A personal view on systems medicine and the emergence of proactive P4 medicine: predictive, preventive, personalized and participatory

(2012) Leroy Hood et al.   New Biotechnology

The UK Adult Twin Registry (TwinsUK Resource)

(2012) Alireza Moayyeri et al.   Twin Research and Human Genetics

Serum levels of total p-cresylsulphate are associated with angiographic coronary atherosclerosis severity in stable angina patients with early stage of renal failure

(2010) Chao-Ping Wang et al.   ATHEROSCLEROSIS

p-Cresyl sulphate and indoxyl sulphate predict progression of chronic kidney disease

(2010) I.-W. Wu et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Ranking 37th — Measuring the Performance of the U.S. Health Care System

(2010) Christopher J.L. Murray et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Glycobiome of the Rumen Bacterium Butyrivibrio proteoclasticus B316T Highlights Adaptation to a Polysaccharide-Rich Environment

(2010) William J. Kelly et al.   PLoS One

Rank-Based Inverse Normal Transformations are Increasingly Used, But are They Merited?

(2009) T. Mark Beasley et al.   BEHAVIOR GENETICS

Butyrate Improves Insulin Sensitivity and Increases Energy Expenditure in Mice

(2009) Z. Gao et al.   DIABETES

Uremic toxins originating from colonic microbial metabolism

(2009) Pieter Evenepoel et al.   KIDNEY INTERNATIONAL

Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites

(2009) W. R. Wikoff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fast unfolding of communities in large networks

(2008) Vincent D Blondel et al.   JOURNAL OF STATISTICAL MECHANICS-THEORY AND EXPERIMENT