Article
Infectious Diseases
Marco Lollobrigida, Gianluca Pingitore, Luca Lamazza, Giulia Mazzucchi, Giorgio Serafini, Alberto De Biase
Summary: The benefit of antibiotic prophylaxis for most oral surgical procedures is controversial, with substantial agreement found in some clinical scenarios but discordant responses in others. Specific guidelines on antibiotics in dentistry, particularly on antibiotic prophylaxis in oral surgery, are needed to avoid unnecessary prescriptions, as indicated by the heterogeneous responses collected from the survey sample.
Article
Surgery
Susan L. Feldt, Robert Keskey, Pranav Krishnan, Neil H. Hyman, Benjamin D. Shogan
Summary: This study found that previous postoperative infection is an independent risk factor for subsequent postoperative infections and is associated with resistance to standard prophylaxis. Therefore, individualized antibiotic prophylaxis is necessary for patients with previous postoperative infections.
JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
(2022)
Article
Clinical Neurology
Jennyfer A. Mitterer, Bernhard J. H. Frank, Susana Gardete-Hartmann, Lukas F. Panzenboeck, Sebastian Simon, Petra Krepler, Jochen G. Hofstaetter
Summary: This study analyzed the changes in microbiological spectrum and antibiotic resistance pattern in patients who underwent multiple revision surgeries for the treatment of postoperative spinal implant infections (PSII). The findings suggest that changes in microbiological spectrum and antibiotic resistance pattern can occur in severe PSII cases that require multiple revision surgeries. These findings are important for guiding antimicrobial treatment in PSII.
Review
Infectious Diseases
Anastasia Murtha-Lemekhova, Juri Fuchs, Miriam Teroerde, Ute Chiriac, Rosa Klotz, Daniel Hornuss, Jan Larmann, Markus A. Weigand, Katrin Hoffmann
Summary: This systematic review and meta-analysis assessed the efficacy of prophylactic antibiotics after hepatectomy. The results showed that routine prophylactic antibiotic use does not reduce postoperative infection or liver-specific complications, but contributes to bacterial resistance. Further research on individualized risk-adapted antibiotic prophylaxis strategies is needed to optimize perioperative treatment in liver surgery.
Article
Gastroenterology & Hepatology
Javier Martinez, Virginia Hernandez-Gea, Enrique Rodriguez-de-Santiago, Luis Tellez, Bogdan Procopet, Alvaro Giraldez, Lucio Amitrano, Candid Villanueva, Dominique Thabut, Luis Ibanez-Samaniego, Gilberto Silva-Junior, Joan Genesca, Christophe Bureau, Jonel Trebicka, Rafael Banares, Aleksander Krag, Elba Llop, Wim Laleman, Jose Maria Palazon, Jose Castellote, Susana Rodrigues, Lise L. Gluud, Carlos Noronha-Ferreira, Nuria Canete, Manuel Rodriguez, Arnulf Ferlitsch, Remy Schwarzer, Jose Luis Mundi, Henning Gronbaek, Manuel Hernandez-Guerra, Romano Sassatelli, Alessandra Dell'Era, Marco Senzolo, Juan G. Abraldes, Manuel Romero-Gomez, Alexander Zipprich, Meritxell Casas, Helena Masnoun, Massimo Primignani, Frederik Nevens, Jose Luis Calleja, Christian Jansen, Marie Angele Robic, Irene Conejo, Maria Vega Catalina, Marika Rudler, Edilmar Alvarado, Valeria Perez-Campuzano, Maria Anna Guardascione, Petra Fischer, Jaime Bosch, Juan Carlos Garcia-Pagan, Agustin Albillos
Summary: Despite antibiotic prophylaxis, nearly 20% of patients with acute variceal bleeding develop bacterial infections during hospitalization. Respiratory bacterial infections are the most common, occurring early after admission. Respiratory infection is associated with advanced liver disease, severe hepatic encephalopathy, and the use of nasogastric tube, orotracheal intubation for endoscopy, or esophageal balloon tamponade.
JOURNAL OF HEPATOLOGY
(2021)
Article
Infectious Diseases
Angel Orion Salgado-Peralvo, Naresh Kewalramani, Juan Francisco Pena-Cardelles, Maria Victoria Mateos-Moreno, Loreto Monsalve-Guil, Alvaro Jimenez-Guerra, Ivan Ortiz-Garcia, Eugenio Velasco-Ortega
Summary: Professionals in oral implantology frequently prescribe preventive antibiotics in both healthy and at-risk patients; amoxicillin is the most commonly used antibiotic, while clindamycin is the most commonly used antibiotic in patients with allergies; antibiotics are often used by professionals in oral implantology both preoperatively and postoperatively.
Review
Dentistry, Oral Surgery & Medicine
Iciar Arteagoitia, Fabio Rodriguez Sanchez, Amaia Figueras, Nagore Arroyo-Lamas
Summary: The effectiveness of oral clindamycin in preventing infection after oral surgery, except for third molar extraction, is limited.
CLINICAL ORAL INVESTIGATIONS
(2022)
Article
Dentistry, Oral Surgery & Medicine
Sahyun Sung, Eun Hwa Kim, Ji-Won Kwon, Jung-Seok Lee, Soo-Bin Lee, Seong-Hwan Moon, Hwan-Mo Lee, Inkyung Jung, Byung Ho Lee
Summary: Invasive dental procedures do not increase the risk of postoperative spinal infection, and antibiotic prophylaxis before dental procedures is not effective in preventing spinal infection, according to an analysis of 229,335 patients who underwent spinal surgery from 2010 to 2017.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2021)
Article
Orthopedics
Anna Stephan, Alexander Thuermer, Ingmar Glauche, Joerg Nowotny, Stefan Zwingenberger, Maik Stiehler
Summary: The study evaluated the impact of prophylactic antibiotics and antibiotic therapy on sonicate fluid cultures in patients with implant-associated infection. The results showed that antibiotic treatment did not significantly affect the detection rate of infectious agents, and sonicate fluid cultures were able to detect pathogens that conventional tissue cultures failed to identify.
JOURNAL OF ORTHOPAEDIC RESEARCH
(2021)
Article
Medicine, General & Internal
Sung-Woo Choi, Jae Chul Lee, Won Seok Lee, Jin Yeong Hwang, Min Jung Baek, Yoon Seo Choi, Hae-Dong Jang, Byung-Joon Shin
Summary: This study compared the clinical features, treatment course, and prognosis of delayed postoperative spinal infection (PSI) with acute PSI. The results showed that delayed-onset PSI requires more extensive and longer treatment than acute-onset PSI, including revision surgery and additional instrumentation. The causative organisms and clinical manifestations did not differ between the two groups.
Article
Urology & Nephrology
Riccardo Bartoletti, Francesco Claps, Gabriele Tulone, Alessandro Perotti, Alessandro Zucchi, Niccolo Riccardi, Vincenzo Ficarra, Cosimo De Nunzio, Andrea Tubaro, Alchiede Simonato
Summary: The effects of different antibiotic prophylaxis regimens in DM patients undergoing TRUSPB were investigated. The results showed that fluoroquinolones were effective in antibiotic prophylaxis for diabetic patients undergoing TRUSPB, regardless of the level of bacterial resistance in the community.
WORLD JOURNAL OF UROLOGY
(2022)
Review
Pharmacology & Pharmacy
Mohammad Abavisani, Reza Khayami, Melika Hoseinzadeh, Mansoor Kodori, Prashant Kesharwani, Amirhossein Sahebkar
Summary: The increasing global trends of antibiotic resistance (AR) and its destructive impact on patients and healthcare systems underscore the need for new strategies. Understanding bacterial resistance mechanisms and accurate diagnosis can enhance the effectiveness of novel strategies. The transfer of antimicrobial resistance genes (ARGs) is a significant factor in disseminating AR. The CRISPR-Cas system, as part of the bacterial immune system, shows promise in removing ARGs and presents an innovative strategy in the battle against antibiotic resistance.
DRUG RESISTANCE UPDATES
(2023)
Article
Infectious Diseases
Daniel J. G. Thirion, Jean-Alexandre Caissy, Florence Poulin, Camille S. H. Lanfranchi, Albin Deda, Armen Aprikian, Charles Frenette, Sero Andonian
Summary: The study compared the impact of augmented prophylaxis (ciprofloxacin with an aminoglycoside) and empirical prophylaxis (ciprofloxacin alone) on post-prostate biopsy infectious complication rates. A total of 2835 patients were evaluated in a retrospective cohort study, and the results showed that augmented prophylaxis was associated with significantly lower rates of infectious complications compared to empirical prophylaxis. Risk factors such as recent fluoroquinolone use and previous urinary tract infection also had a significant impact on infection rates.
Review
Medicine, General & Internal
Lukasz Bialek, Marta Rydzinska, Malte W. Vetterlein, Jakub Dobruch, Michal A. Skrzypczyk
Summary: In the era of antibiotic overuse and increasing antibiotic resistance, there is a lack of evidence regarding postoperative antibiotic prophylaxis after urethral reconstruction. This systematic review aimed to evaluate the effectiveness and relevance of postoperative antibiotic prophylaxis in male pediatric and adult urethral reconstruction.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Oncology
Abida K. Sattar, Taleaa Masroor, Russell Seth Martins, Nida Zahid, Hania Shahzad, Rufina Soomro, Omema Saleem, Lubna M. Vohra, Sana Zeeshan, Muhammad Areeb Ashfaq, Irum Khan, Rida Nadeem, Nikhat Fatima, Ayisha Afzal Qureshi, Farin F. Amersi, Syed Faisal Mahmood
Summary: This study investigated the utility of continued antibiotic prophylaxis after mastectomy without immediate reconstruction and with indwelling drains. The results showed that continued antibiotic prophylaxis did not provide additional benefits in reducing surgical site infection rates.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Fabio Rodriguez Sanchez, Iciar Arteagoitia, Carlos Rodriguez Andres, Josef Bruers
Article
Multidisciplinary Sciences
Fabio Rodriguez Sanchez, Iciar Arteagoitia, Wim Teughels, Carlos Rodriguez Andres, Marc Quirynen
Article
Infectious Diseases
Nagore Arroyo-Lamas, Unai Ugalde, Iciar Arteagoitia
Article
Biochemistry & Molecular Biology
Nagore Arroyo-Lamas, Iciar Arteagoitia, Unai Ugalde
Summary: LED-based UVC irradiation effectively decontaminates titanium surfaces, reducing carbon content and improving chemical features, regardless of surface type.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Immunology
Fabio Rodriguez Sanchez, Tim Verspecht, Ana B. Castro, Martine Pauwels, Carlos Rodriguez Andres, Marc Quirynen, Wim Teughels
Summary: L-PRF exudate exhibits antimicrobial activity against P. gingivalis by releasing hydrogen peroxide and antimicrobial peptides. In developing multi-species biofilms, its antimicrobial effect is blocked only by peroxidase, leading to an increase in P. gingivalis growth.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2021)
Review
Dentistry, Oral Surgery & Medicine
Iciar Arteagoitia, Fabio Rodriguez Sanchez, Amaia Figueras, Nagore Arroyo-Lamas
Summary: The effectiveness of oral clindamycin in preventing infection after oral surgery, except for third molar extraction, is limited.
CLINICAL ORAL INVESTIGATIONS
(2022)
Article
Dentistry, Oral Surgery & Medicine
Gorka Santamaria Arrieta, Fabio Rodriguez Sanchez, Carlos Rodriguez-Andres, Luis Barbier, Iciar Arteagoitia
Summary: This study found that preoperative oral clindamycin administration during dental implant surgery in healthy adults may not reduce early implant failure or postoperative complications.
CLINICAL ORAL INVESTIGATIONS
(2023)