Identification of a proton sensor that regulates conductance and open time of single hERG channels

Extracellular protons accelerate hERG channel deactivation by destabilizing voltage sensor relaxation

(2018) Yu Patrick Shi et al.   JOURNAL OF GENERAL PHYSIOLOGY

External protons destabilize the activated voltage sensor in hERG channels

(2013) Yu Patrick Shi et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

External pH modulates EAG superfamily K+channels through EAG-specific acidic residues in the voltage sensor

(2013) Marcin Kazmierczak et al.   JOURNAL OF GENERAL PHYSIOLOGY

Proton block of the pore underlies the inhibition of hERG cardiac K+ channels during acidosis

(2012) Aaron C. Van Slyke et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Enhanced inhibitory effect of acidosis on hERG potassium channels that incorporate the hERG1b isoform

(2011) C.Y. Du et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Regulation of the voltage-insensitive step of HERG activation by extracellular pH

(2010) Qinlian Zhou et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Acidosis Impairs the Protective Role of hERG K+ Channels Against Premature Stimulation

(2010) CHUN YUN DU et al.   JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY

Protein Ionizable Groups: pKValues and Their Contribution to Protein Stability and Solubility

(2009) C. Nick Pace et al.   JOURNAL OF BIOLOGICAL CHEMISTRY