β-catenin signaling inhibitors ICG-001 and C-82 improve fibrosis in preclinical models of endometriosis
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Title
β-catenin signaling inhibitors ICG-001 and C-82 improve fibrosis in preclinical models of endometriosis
Authors
Keywords
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Journal
Scientific Reports
Volume 9, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-12-27
DOI
10.1038/s41598-019-56302-4
References
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Related references
Note: Only part of the references are listed.- Recent Development of Wnt Signaling Pathway Inhibitors for Cancer Therapeutics
- (2019) Jerry Harb et al. Current Oncology Reports
- Inhibition of canonical WNT signaling pathway by β-catenin/CBP inhibitor ICG-001 ameliorates liver fibrosis in vivo through suppression of stromal CXCL12
- (2018) Büsra Öztürk Akcora et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Secreted frizzled-related protein 2 (SFRP2) expression promotes lesion proliferation via canonical WNT signaling and indicates lesion borders in extraovarian endometriosis
- (2018) T Heinosalo et al. HUMAN REPRODUCTION
- Inhibition of Wnt/β-catenin signaling suppresses myofibroblast differentiation of lung resident mesenchymal stem cells and pulmonary fibrosis
- (2018) Honghui Cao et al. Scientific Reports
- Wnt/β-Catenin Signaling as a Potential Target for the Treatment of Liver Cirrhosis Using Antifibrotic Drugs
- (2018) Koji Nishikawa et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Arcyriaflavin a, a cyclin D1–cyclin-dependent kinase4 inhibitor, induces apoptosis and inhibits proliferation of human endometriotic stromal cells: a potential therapeutic agent in endometriosis
- (2017) Tomoko Hirakawa et al. Reproductive Biology and Endocrinology
- Selective inhibitor of Wnt/β-catenin/CBP signaling ameliorates hepatitis C virus-induced liver fibrosis in mouse model
- (2017) Yuko Tokunaga et al. Scientific Reports
- Safety, Tolerability, and Preliminary Efficacy of the Anti-Fibrotic Small Molecule PRI-724, a CBP/β-Catenin Inhibitor, in Patients with Hepatitis C Virus-related Cirrhosis: A Single-Center, Open-Label, Dose Escalation Phase 1 Trial
- (2017) Kiminori Kimura et al. EBioMedicine
- Epigenetic Modulation of Collagen 1A1: Therapeutic Implications in Fibrosis and Endometriosis1
- (2016) Ye Zheng et al. BIOLOGY OF REPRODUCTION
- Intracellular Wnt/Beta-Catenin Signaling Underlying 17beta-Estradiol-Induced Matrix Metalloproteinase 9 Expression in Human Endometriosis1
- (2016) Ling Zhang et al. BIOLOGY OF REPRODUCTION
- On the Dependency of Cellular Protein Levels on mRNA Abundance
- (2016) Yansheng Liu et al. CELL
- miR-503, a microRNA epigenetically repressed in endometriosis, induces apoptosis and cell-cycle arrest and inhibits cell proliferation, angiogenesis, and contractility of human ovarian endometriotic stromal cells
- (2016) Tomoko Hirakawa et al. HUMAN REPRODUCTION
- 17 β-Estradiol promotes vascular endothelial growth factor expression via the Wnt/β-catenin pathway during the pathogenesis of endometriosis
- (2016) Ling Zhang et al. MOLECULAR HUMAN REPRODUCTION
- Inhibition of Cyclic Adenosine Monophosphate (cAMP)-response Element-binding Protein (CREB)-binding Protein (CBP)/β-Catenin Reduces Liver Fibrosis in Mice
- (2015) Yosuke Osawa et al. EBioMedicine
- Safely targeting cancer stem cells via selective catenin coactivator antagonism
- (2014) Heinz-Josef Lenz et al. CANCER SCIENCE
- Parthenolide reduces cell proliferation and prostaglandin estradiol synthesis in human endometriotic stromal cells and inhibits development of endometriosis in the murine model
- (2013) Eri Takai et al. FERTILITY AND STERILITY
- Endometriosis: pathogenesis and treatment
- (2013) Paolo Vercellini et al. Nature Reviews Endocrinology
- Small-molecule inhibition of CBP/catenin interactions eliminates drug-resistant clones in acute lymphoblastic leukemia
- (2013) E J Gang et al. ONCOGENE
- In Vitro Effects of a Small-Molecule Antagonist of the Tcf/ß-Catenin Complex on Endometrial and Endometriotic Cells of Patients with Endometriosis
- (2013) Sachiko Matsuzaki et al. PLoS One
- Involvement of the Wnt/β-Catenin Signaling Pathway in the Cellular and Molecular Mechanisms of Fibrosis in Endometriosis
- (2013) Sachiko Matsuzaki et al. PLoS One
- Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis
- (2012) Alfiya Akhmetshina et al. Nature Communications
- Fasudil Inhibits the Proliferation and Contractility and Induces Cell Cycle Arrest and Apoptosis of Human Endometriotic Stromal Cells: A Promising Agent for the Treatment of Endometriosis
- (2011) Akitoshi Tsuno et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Impaired Down-Regulation of E-Cadherin and β-Catenin Protein Expression in Endometrial Epithelial Cells in the Mid-Secretory Endometrium of Infertile Patients with Endometriosis
- (2010) Sachiko Matsuzaki et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Inhibition of Wnt/ -catenin/CREB binding protein (CBP) signaling reverses pulmonary fibrosis
- (2010) W. R. Henderson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Heparin is a promising agent for the treatment of endometriosis-associated fibrosis
- (2009) Kaei Nasu et al. FERTILITY AND STERILITY
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