The Molecular and Physiological Effects of Protein-Derived Polyamines in the Intestine

Polyamines and eIF5A Hypusination Modulate Mitochondrial Respiration and Macrophage Activation

(2019) Daniel J. Puleston et al.   Cell Metabolism

The metabolomic signature of extreme longevity: naked mole rats versus mice

(2019) Mélanie Viltard et al.   Aging-US

Nutrient regulation of mTORC1 at a glance

(2019) Kendall J. Condon et al.   JOURNAL OF CELL SCIENCE

Protein intake trends and conformity with the Dietary Reference Intakes in the United States: analysis of the National Health and Nutrition Examination Survey, 2001–2014

(2018) Claire E Berryman et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Protein fermentation in the gut; implications for intestinal dysfunction in humans, pigs and poultry

(2018) Myrthe Suzanne Gilbert et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Time-course responses of ileal and fecal microbiota and metabolite profiles to antibiotics in cannulated pigs

(2018) Kan Gao et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Spermidine ameliorates the neuronal aging by improving the mitochondrial function in vitro

(2018) Yu-Hong Jing et al.   EXPERIMENTAL GERONTOLOGY

The Traffic Jam: Polyamine Prevalence Pauses Protein Production

(2018) Srivats Venkataramanan et al.   MOLECULAR CELL

Polyamine Control of Translation Elongation Regulates Start Site Selection on Antizyme Inhibitor mRNA via Ribosome Queuing

(2018) Ivaylo P. Ivanov et al.   MOLECULAR CELL

Amino Acid Absorption in the Large Intestine of Humans and Porcine Models

(2017) Nikkie van der Wielen et al.   JOURNAL OF NUTRITION

International Society of Sports Nutrition Position Stand: protein and exercise

(2017) Ralf Jäger et al.   Journal of the International Society of Sports Nutrition

eIF5A Functions Globally in Translation Elongation and Termination

(2017) Anthony P. Schuller et al.   MOLECULAR CELL

mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer

(2017) Amaia Zabala-Letona et al.   NATURE

Amino acid substrates impose polyamine, eIF5A, or hypusine requirement for peptide synthesis

(2017) Byung-Sik Shin et al.   NUCLEIC ACIDS RESEARCH

Ornithine decarboxylase regulates M1 macrophage activation and mucosal inflammation via histone modifications

(2017) Dana M. Hardbower et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Colonic Absorption of Low-Molecular-Weight Metabolites Influenced by the Intestinal Microbiome: A Pilot Study

(2017) Mitsuharu Matsumoto et al.   PLoS One

Spermine cycling in mitochondria is mediated by adenine nucleotide translocase activity: mechanism and pathophysiological implications

(2016) Silvia Grancara et al.   AMINO ACIDS

Effect of oral polyamine supplementation pre-weaning on piglet growth and intestinal characteristics

(2016) W. H. E. J. van Wettere et al.   Animal

Exogenous spermine inhibits hypoxia/ischemia-induced myocardial apoptosis via regulation of mitochondrial permeability transition pore and associated pathways

(2016) Can Wei et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Functions of Polyamines in Mammals

(2016) Anthony E. Pegg   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting eIF5A Hypusination Prevents Anoxic Cell Death through Mitochondrial Silencing and Improves Kidney Transplant Outcome

(2016) Nicolas Melis et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Cardioprotection and lifespan extension by the natural polyamine spermidine

(2016) Tobias Eisenberg et al.   NATURE MEDICINE

A reference gene catalogue of the pig gut microbiome

(2016) Liang Xiao et al.   Nature Microbiology

ATM mediates spermidine-induced mitophagy via PINK1 and Parkin regulation in human fibroblasts

(2016) Yongmei Qi et al.   Scientific Reports

Energy metabolism in intestinal epithelial cells during maturation along the crypt-villus axis

(2016) Huansheng Yang et al.   Scientific Reports

The role of protein in weight loss and maintenance

(2015) Heather J Leidy et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Spermine selectively inhibits high-conductance, but not low-conductance calcium-induced permeability transition pore

(2015) Pia A. Elustondo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Metabolism Links Bacterial Biofilms and Colon Carcinogenesis

(2015) Caroline H. Johnson et al.   Cell Metabolism

A novel enzyme with spermine oxidase properties in bovine liver mitochondria: Identification and kinetic characterization

(2015) Emanuela Bonaiuto et al.   FREE RADICAL BIOLOGY AND MEDICINE

Remaining Mysteries of Molecular Biology: The Role of Polyamines in the Cell

(2015) Leonor Miller-Fleming et al.   JOURNAL OF MOLECULAR BIOLOGY

Digestibility Issues of Vegetable versus Animal Proteins: Protein and Amino Acid Requirements—Functional Aspects

(2015) Daniel Tomé   FOOD AND NUTRITION BULLETIN

Interaction between dietary protein content and the source of carbohydrates along the gastrointestinal tract of weaned piglets

(2014) Robert Pieper et al.   ARCHIVES OF ANIMAL NUTRITION

Spermidine induces autophagy by inhibiting the acetyltransferase EP300

(2014) F Pietrocola et al.   CELL DEATH AND DIFFERENTIATION

Akt and Erk1/2 activate the ornithine decarboxylase/polyamine system in cardioprotective ischemic preconditioning in rats: the role of mitochondrial permeability transition pores

(2014) Hao Zhang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Polyamines in human breast milk for preterm and term infants

(2013) J. Plaza-Zamora et al.   BRITISH JOURNAL OF NUTRITION

Toxicity of Polyamines and Their Metabolic Products

(2013) Anthony E. Pegg   CHEMICAL RESEARCH IN TOXICOLOGY

Polyamines: Emerging players in bacteria–host interactions

(2013) Maria Letizia Di Martino et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

The autophagy enhancer spermidine reverses arterial aging

(2013) Thomas J. LaRocca et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Protein-protein-interaction Network Organization of the Hypusine Modification System

(2012) Henning Sievert et al.   MOLECULAR & CELLULAR PROTEOMICS

Impact of Intestinal Microbiota on Intestinal Luminal Metabolome

(2012) Mitsuharu Matsumoto et al.   Scientific Reports

Mitochondrial oxidative stress induced by Ca2+ and monoamines: different behaviour of liver and brain mitochondria in undergoing permeability transition

(2011) Silvia Grancara et al.   AMINO ACIDS

Spermidine and resveratrol induce autophagy by distinct pathways converging on the acetylproteome

(2011) Eugenia Morselli et al.   JOURNAL OF CELL BIOLOGY

Polyamine transport is mediated by both endocytic and solute carrier transport mechanisms in the gastrointestinal tract

(2010) Takeshi Uemura et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Preliminary kinetic characterization of a copper amine oxidase from rat liver mitochondria matrix

(2010) Roberto Stevanato et al.   AMINO ACIDS

Inactivation of eukaryotic initiation factor 5A (eIF5A) by specific acetylation of its hypusine residue by spermidine/spermine acetyltransferase 1 (SSAT1)

(2010) Seung Bum Lee et al.   BIOCHEMICAL JOURNAL

Polyamines regulate E-cadherin transcription through c-Myc modulating intestinal epithelial barrier function

(2009) Lan Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Functional significance of eIF5A and its hypusine modification in eukaryotes

(2009) M. H. Park et al.   AMINO ACIDS

Mammalian polyamine metabolism and function

(2009) Anthony E. Pegg   IUBMB LIFE

Induction of autophagy by spermidine promotes longevity

(2009) Tobias Eisenberg et al.   NATURE CELL BIOLOGY

Effects of dietary polyamines at physiologic doses in early-weaned piglets

(2009) María Sabater-Molina et al.   NUTRITION

Spermidine/spermine-N1-acetyltransferase: a key metabolic regulator

(2008) Anthony E. Pegg   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Ca2+-independent effects of spermine on pyruvate dehydrogenase complex activity in energized rat liver mitochondria incubated in the absence of exogenous Ca2+ and Mg2 +

(2008) E. Pezzato et al.   AMINO ACIDS

Structural Basis for Putrescine Activation of HumanS-Adenosylmethionine Decarboxylase†‡

(2008) Shridhar Bale et al.   BIOCHEMISTRY

Identification and Characterization of a Diamine Exporter in Colon Epithelial Cells

(2008) Takeshi Uemura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ActivatedK-RAS increases polyamine uptake in human colon cancer cells through modulation of caveolar endocytosis

(2008) Upal K. Basu Roy et al.   MOLECULAR CARCINOGENESIS

uORFs with unusual translational start codons autoregulate expression of eukaryotic ornithine decarboxylase homologs

(2008) I. P. Ivanov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA