Article
Multidisciplinary Sciences
Kabir Ahmad, Enamul Kabir, Syed Afroz Keramat, Rasheda Khanam
Summary: The study found that poor maternal physical and mental health during or up to 15 months after childbirth was associated with adverse health outcomes for their offspring, including poor general health, presence of chronic health conditions, and lower physical health scores. Additionally, the presence of a chronic condition in mothers during pregnancy significantly increased the likelihood of their offspring having a chronic condition in infancy and adolescence. Stressful life events and mental health issues in mothers were also found to impact the health of their children during adolescence and infancy, respectively.
Article
Obstetrics & Gynecology
Rebecka Bramsved, Staffan Marild, Maria Bygdell, Jenny M. Kindblom, Ingela Lindh
Summary: This study examined the impact of body mass index (BMI) and smoking during adolescence on future birth weight. The results showed that BMI and smoking at the start of pregnancy were strongly associated with birth weight, while BMI and smoking at 19 years of age did not show this association.
BMC PREGNANCY AND CHILDBIRTH
(2023)
Article
Environmental Sciences
Keiko Yamasaki, Naomi Mitsuda, J-P Naw Awn, Masamitsu Eitoku, Nagamasa Maeda, Mikiya Fujieda, Narufumi Suganuma
Summary: This study found a positive correlation between maternal urinary cotinine concentration and placental weight and the ratio of placental weight to birth weight. After reaching a certain concentration, placental weight decreased in male offspring while it plateaued in female offspring. Active smoking during pregnancy significantly increased both placental weight and placental weight to birth weight ratio.
ENVIRONMENTAL RESEARCH
(2022)
Article
Multidisciplinary Sciences
Aderonke A. Akinkugbe, Tegwyn H. Brickhouse, Dipankar Bandyopadhyay, Marcelle M. Nascimento, Gary D. Slade
Summary: Pre-existing maternal overweight/obesity and gestational weight gain are associated with the risk of early childhood caries, but there is currently insufficient evidence to demonstrate the impact of prepregnancy BMI and gestational weight gain on offspring caries experience risk.
Article
Environmental Sciences
Yuki Kunori, Yasuaki Saijo, Eiji Yoshioka, Yukihiro Sato, Tomoko Kanaya, Kentaro Nakanishi, Yasuhito Kato, Ken Nagaya, Satoru Takahashi, Yoshiya Ito, Sachiko Itoh, Sumitaka Kobayashi, Chihiro Miyashita, Atsuko Ikeda-Araki, Reiko Kishi
Summary: This study aimed to investigate the relationship between urinary cotinine concentration (UCC) during pregnancy and adverse birth outcomes related to fetal growth. The study found dose-response relationships between UCC and the risks of preterm birth, low birth weight, and small-for-gestational age.
ENVIRONMENTAL RESEARCH
(2022)
Review
Pediatrics
Hong-Kun Di, Yong Gan, Kai Lu, Chao Wang, Yi Zhu, Xin Meng, Wen-Qi Xia, Min-Zhi Xu, Jing Feng, Qing-Feng Tian, Yan He, Zhi-Qiang Nie, Jun-An Liu, Fu-Jian Song, Zu-Xun Lu
Summary: This study systematically explored the association between maternal smoking during pregnancy and the risk of low birth weight (LBW) in offspring globally. The results showed a significant association between maternal smoking during pregnancy and the risk of LBW in offspring. There was also a dose-response relationship, with a higher risk observed for longer duration and higher amount of smoking.
WORLD JOURNAL OF PEDIATRICS
(2022)
Article
Endocrinology & Metabolism
Dingyu Cui, Wen Yang, Ping Shao, Jing Li, Peng Wang, Junhong Leng, Shuo Wang, Enqing Liu, Juliana C. N. Chan, Zhijie Yu, Gang Hu, Xilin Yang
Summary: Prepregnancy overweight/obesity was synergistically associated with an increased risk of macrosomia in Chinese women who also engaged in passive smoking during pregnancy, with the majority of the association remaining unchanged by hyperglycemia during pregnancy.
Article
Environmental Sciences
Weeberb J. Requia, Petros Koutrakis, Stefania Papatheodorou
Summary: This study examines the association between Low Birth Weight (LBW) and ambient temperature exposure in Brazil, the largest county in South America. The results indicate that there is a significant positive association between LBW and ambient temperature, specifically in the northern region where the Amazon is located.
ENVIRONMENTAL RESEARCH
(2022)
Article
Public, Environmental & Occupational Health
Yunyun Luo, Yuelun Zhang, Hui Pan, Shi Chen
Summary: The study found that pregnant women exposed to PM2.5 during pregnancy were at an increased risk of macrosomia in both the entire pregnancy and the first trimester. Maternal exposure to SHS during pregnancy enhances the impact of PM2.5 air pollutants on the risk of macrosomia, with a stronger interaction between the two pollutants as the frequency of SHS exposure increases.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Public, Environmental & Occupational Health
Yuko Minami, Minoru Miyashita, Takanori Ishida, Megumi Fujita, Hirotaka Hamada, Masatoshi Saito, Takahiro Arima, Nobuo Yaegashi
Summary: Breastfeeding has numerous benefits but there is limited data on the maternal factors influencing it. This study aimed to investigate the associations between maternal lifestyle and diet during pregnancy and exclusive breastfeeding (EBF). The findings suggest that maternal lifestyles during pregnancy can affect lactation performance, and making adjustments in lifestyle during pregnancy can have positive effects on both maternal and children's health through successful breastfeeding.
PREVENTIVE MEDICINE
(2023)
Article
Endocrinology & Metabolism
Yuanyuan Zhang, Hong Mei, Ke Xu, Chunan Li, Zhiguo Xia, Yafei Tan, Shaoping Yang, Jianduan Zhang
Summary: This study found that maternal gestational weight gain, infant birth weight, and postnatal weight change mediated the effects of maternal prepregnancy BMI on childhood BMI. Interventions targeting these factors can mitigate the risk of childhood obesity.
Review
Nutrition & Dietetics
Siti Helmyati, Maria Wigati, Muhammad Hafizh Hariawan, Erri Larene Safika, Mira Dewi, Cindra Tri Yuniar, Trias Mahmudiono
Summary: This study examined the association between maternal health behaviors and neonatal outcomes among the Indonesian population through a meta-analysis. The results showed that pregnant women with incomplete antenatal care had a higher risk of low birth weight and neonatal mortality, and those who were passively exposed to smoking were also at higher risk of low birth weight.
Article
Medical Laboratory Technology
Xiaoxue Wang, Yudong Pu, Shiwei Ai, Haixia Liu, Shuzhen He, Zhilan Li, Yuhui Dang
Summary: This study found that mercury exposure is associated with preeclampsia and adverse birth outcomes. Pregnant women with higher levels of mercury in their blood are more likely to develop mild and severe preeclampsia, as well as have low birth weight and preterm birth.
CLINICA CHIMICA ACTA
(2022)
Article
Substance Abuse
Laura R. Stroud, George D. Papandonatos, Nancy C. Jao, Raymond Niaura, Stephen Buka, Neal L. Benowitz
Summary: This study found that the association between prenatal cigarette smoking and birth weight is moderated by maternal nicotine metabolism phenotype, especially for women with slower nicotine metabolism. Additionally, race also plays a role in these associations.
DRUG AND ALCOHOL DEPENDENCE
(2022)
Article
Nutrition & Dietetics
Carolina Molto-Puigmarti, Rima Obeid, Monique Mommers, Simone J. P. M. Eussen, Carel Thijs
Summary: Adequate choline and betaine levels during pregnancy are essential for fetal growth and development. Maternal plasma choline and betaine levels in the third trimester were found to be positively associated with childhood anthropometric measures, with some associations persisting up to 8 years of age, particularly in boys. Further studies are needed to explore the validity of maternal plasma choline and betaine concentrations as markers of maternal intake and fetal transfer.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2021)
Article
Environmental Sciences
Lizan D. Bloemsma, Alet H. Wijga, Jochem O. Klompmaker, Gerard Hoek, Nicole A. H. Janssen, Erik Lebret, Bert Brunekreef, Ulrike Gehring
Summary: Long-term exposure to residential green space, ambient air pollution, and traffic noise may be associated with mental wellbeing in adolescents. Living near green spaces, especially those further away from home, is associated with better mental wellbeing, while higher air pollution and traffic noise levels are associated with poorer mental wellbeing.
ENVIRONMENT INTERNATIONAL
(2022)
Article
Environmental Sciences
Adjani A. Peralta, Joel Schwartz, Diane R. Gold, Judith M. Vonk, Roel Vermeulen, Ulrike Gehring
Summary: This study found suggestive associations between early childhood exposure to ambient air pollution and the distribution of CIMT in adolescence. Specifically, exposure to PM2.5 absorbance was significantly associated with the 10th quantile of CIMT, while no significant associations were observed with other quantiles.
ENVIRONMENT INTERNATIONAL
(2022)
Correction
Environmental Sciences
Jochem O. Klompmaker, Nicole A. H. Janssen, Lizan D. Bloemsma, Ulrike Gehring, Alet H. Wijga, Carolien van den Brink, Erik Lebret, Bert Brunekreef, Gerard Hoek
ENVIRONMENTAL HEALTH PERSPECTIVES
(2022)
Article
Respiratory System
Evelien R. van Meel, Sara M. Mensink-Bout, Herman T. den Dekker, Tarunveer S. Ahluwalia, Isabella Annesi-Maesano, Syed Hasan Arshad, Nour Baiz, Henrique Barros, Andrea von Berg, Hans Bisgaard, Klaus Bonnelykke, Christian J. Carlsson, Maribel Casas, Leda Chatzi, Cecile Chevrier, Geertje Dalmeijer, Carol Dezateux, Karel Duchen, Merete Eggesbo, Cornelis van der Ent, Maria Fantini, Claudia Flexeder, Urs Frey, Fransesco Forastiere, Ulrike Gehring, Davide Gori, Raquel Granell, Lucy J. Griffiths, Hazel Inskip, Joanna Jerzynska, Anne M. Karvonen, Thomas Keil, Cecily Kelleher, Manolis Kogevinas, Gudrun Koppen, Claudia E. Kuehni, Nathalie Lambrechts, Susanne Lau, Irina Lehmann, Johnny Ludvigsson, Maria Christine Magnus, Erik Melen, John Mehegan, Monique Mommers, Anne-Marie Nybo Andersen, Wenche Nystad, Eva S. L. Pedersen, Juha Pekkanen, Ville Peltola, Katharine C. Pike, Angela Pinot de Moira, Costanza Pizzi, Kinga Polanska, Maja Popovic, Daniela Porta, Graham Roberts, Ana Cristina Santos, Erica S. Schultz, Marie Standl, Jordi Sunyer, Carel Thijs, Laura Toivonen, Eleonora Uphoff, Jakob Usemann, Marina Vafeidi, John Wright, Johan C. de Jongste, Vincent W. V. Jaddoe, Liesbeth Duijts
Summary: Early-life lower respiratory tract infections may increase the risk of asthma and lower lung function in school-age children. The study also found that early-life lower respiratory tract infections have the strongest impact on respiratory diseases in children with wheezing.
EUROPEAN RESPIRATORY JOURNAL
(2022)
Article
Nutrition & Dietetics
Patricia Macchiaverni, Ulrike Gehring, Akila Rekima, Alet H. Wijga, Valerie Verhasselt
Summary: This study investigated the relationship between exposure to house dust mite Der p 1 allergen from different sources during infancy and IgE levels and asthma outcomes in children. The findings suggest that exposure to Der p 1 through human milk is associated with high levels of serum IgE in childhood, while exposure from mattress dust is not.
Letter
Environmental Sciences
Ulrike Gehring, Mireia Gascon
ENVIRONMENTAL HEALTH PERSPECTIVES
(2022)
Review
Respiratory System
Olena Gruzieva, Ayoung Jeong, Shizhen He, Zhebin Yu, Jeroen de Bont, Maria G. M. Pinho, Ikenna C. Eze, Sara Kress, Craig E. Wheelock, Annette Peters, Jelle Vlaanderen, Kees de Hoogh, Augustin Scalbert, Marc Chadeau-Hyam, Roel C. H. Vermeulen, Ulrike Gehring, Nicole Probst-Hensch, Erik Melen
Summary: This study reviews the relationships between air pollution, metabolic profiles, and lung function from a life-course perspective. The findings suggest that a wide range of metabolites are associated with both short-term and long-term exposure to air pollution, and are also linked to lung function and respiratory diseases. However, the existing studies have limitations such as small sample sizes and heterogeneity in exposure assessment. The ongoing EXPANSE project aims to address these shortcomings by combining large European cohorts and harmonized data.
EUROPEAN RESPIRATORY REVIEW
(2022)
Article
Environmental Sciences
Zhebin Yu, Gerard H. Koppelman, Jolanda M. A. Boer, Gerard Hoek, Jules Kerckhoffs, Judith M. Vonk, Roel Vermeulen, Ulrike Gehring
Summary: The study found that long-term exposure to ultrafine particles (UFP) is associated with an increased risk of asthma development, but this association becomes non-significant after adjusting for other pollutants.
ENVIRONMENTAL RESEARCH
(2022)
Article
Critical Care Medicine
Gang Wang, Jenny Hallberg, Rosa Faner, Hans-Jacob Koefoed, Simon Kebede Merid, Susanna Klevebro, Sophia Bjorkander, Olena Gruzieva, Goran Pershagen, Marianne van Hage, Stefano Guerra, Matteo Bottai, Antonios Georgelis, Ulrike Gehring, Anna Bergstrom, Judith M. Vonk, Inger Kull, Gerard H. Koppelman, Alvar Agusti, Erik Melen
Summary: Recent evidence emphasizes the significance of optimal lung development during childhood for lifelong health. This study explored the plasticity of individual lung function states during childhood and found that catch-up and growth failure were associated with respiratory symptoms, airflow limitation, and small airway dysfunction in adulthood.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2023)
Article
Environmental Sciences
Femke Bouma, Gerard Hoek, Gerard H. Koppelman, Judith M. Vonk, Jules Kerckhoffs, Roel Vermeulen, Ulrike Gehring
Summary: This study investigated the association between long-term exposure to ultrafine particles (UFP) and allergic sensitization in children. The findings showed no significant association between UFP exposure and sensitization to inhalant and food allergens. However, NO2, PM2.5, PM2.5 absorbance, and PM10 were found to be associated with sensitization to food allergens.
ENVIRONMENTAL RESEARCH
(2023)
Article
Environmental Sciences
Pauline Kiss, Myrna M. T. de Rooij, Gerard H. Koppelman, Jolanda Boer, Judith M. Vonk, Roel Vermeulen, Lenny Hogerwerf, Hendrika A. M. Sterk, Anke Huss, Lidwien A. M. Smit, Ulrike Gehring
Summary: This study found that adolescents living closer to livestock farms had lower lung function compared to those living farther away. There is an association between closer proximity to farms and poorer lung function.
ENVIRONMENTAL RESEARCH
(2023)
Article
Multidisciplinary Sciences
Merlijn van Breugel, Cancan Qi, Zhongli Xu, Casper-Emil T. Pedersen, Ilya Petoukhov, Judith M. Vonk, Ulrike Gehring, Marijn Berg, Marnix Buegel, Orestes A. Carpaij, Erick Forno, Andreanne Morin, Anders U. Eliasen, Yale Jiang, Maarten Van den Berge, Martijn C. Nawijn, Yang Li, Wei Chen, Louis J. Bont, Klaus Bonnelykke, Juan C. Celedon, Gerard H. Koppelman, Cheng-Jian Xu
Summary: The study demonstrates that nasal DNA methylation is the most accurate predictor for diagnosing childhood allergic diseases, identifying multimorbidity and IgE sensitization, with findings replicated in children of different ages and ethnicities.
NATURE COMMUNICATIONS
(2022)
Article
Environmental Sciences
Apolline Saucy, Ulrike Gehring, Sergio Olmos, Cyrille Delpierre, Jeroen de Bont, Olena Gruzieva, Kees de Hoogh, Anke Huss, Petter Ljungman, Erik Melen, Asa Persson, Inka Pieterson, Marjan Tewis, Zhebin Yu, Roel Vermeulen, Jelle Vlaanderen, Cathryn Tonne
Summary: Residential relocation is used as a natural experiment in epidemiological studies to assess the health impact of environmental changes. Predictors of relocation differ between adult and birth cohorts, and movers tend to experience higher levels of air pollution. Higher socioeconomic position is associated with a higher probability of relocation towards healthier levels of the urban exposome. These findings provide valuable insights for reducing bias in epidemiological studies using relocation as a natural experiment.
ENVIRONMENT INTERNATIONAL
(2023)
Article
Environmental Sciences
Femke Bouma, Nicole A. H. Janssen, Joost Wesseling, Sjoerd van Ratingen, Maciek Strak, Jules Kerckhoffs, Ulrike Gehring, Wouter Hendricx, Kees de Hoogh, Roel Vermeulen, Gerard Hoek
Summary: This study investigated the associations between long-term exposure to ultrafine particles and natural and cause-specific mortality in the Netherlands. The results showed that long-term exposure to ultrafine particles was associated with increased respiratory disease and lung cancer mortality, but a weaker association with cardiovascular disease mortality.
ENVIRONMENT INTERNATIONAL
(2023)
Article
Respiratory System
Ana Maria Vicedo-Cabrera, Erik Melen, Francesco Forastiere, Ulrike Gehring, Klea Katsouyanni, Arzu Yorgancioglu, Charlotte Suppli Ulrik, Kjeld Hansen, Pippa Powell, Brian Ward, Barbara Hoffmann, Zorana Jovanovic Andersen
Summary: Climate change poses a major threat to lung patients, leading to more frequent and extreme weather events, prolonged aeroallergen seasons, and deteriorating air quality. Therefore, immediate action is needed from the healthcare community and policymakers to prepare for a complex future.
EUROPEAN RESPIRATORY JOURNAL
(2023)