Microglia control vascular architecture via a TGFβ1 dependent paracrine mechanism linked to tissue mechanics

Cell adhesion and mechanics as drivers of tissue organization and differentiation: local cues for large scale organization

(2018) Sara A Wickström et al.   CURRENT OPINION IN CELL BIOLOGY

Microglia in the Retina: Roles in Development, Maturity, and Disease

(2018) Sean M. Silverman et al.   Annual Review of Vision Science

Fibroblast growth factor–transforming growth factor beta dialogues, endothelial cell to mesenchymal transition, and atherosclerosis

(2018) Pei-Yu Chen et al.   CURRENT OPINION IN LIPIDOLOGY

Microglia emerge as central players in brain disease

(2017) Michael W Salter et al.   NATURE MEDICINE

The soft mechanical signature of glial scars in the central nervous system

(2017) Emad Moeendarbary et al.   Nature Communications

Retinal vascular and structural changes are associated with amyloid burden in the elderly: ophthalmic biomarkers of preclinical Alzheimer’s disease

(2017) S.Mojtaba Golzan et al.   Alzheimers Research & Therapy

Recent Advances in the Study of Bipolar/Rod-Shaped Microglia and their Roles in Neurodegeneration

(2017) Ngan Pan Bennett Au et al.   Frontiers in Aging Neuroscience

Mechanical characterization of human brain tumors from patients and comparison to potential surgical phantoms

(2017) Daniel C. Stewart et al.   PLoS One

Mechanosensing is critical for axon growth in the developing brain

(2016) David E Koser et al.   NATURE NEUROSCIENCE

Analyzing and interpreting genome data at the network level with ConsensusPathDB

(2016) Ralf Herwig et al.   Nature Protocols

Fate mapping reveals that microglia and recruited monocyte-derived macrophages are definitively distinguishable by phenotype in the retina

(2016) E. G. O’Koren et al.   Scientific Reports

Emergence and subsequent functional specialization of kindlins during evolution of cell adhesiveness

(2015) Julia Meller et al.   MOLECULAR BIOLOGY OF THE CELL

Depression as a Microglial Disease

(2015) Raz Yirmiya et al.   TRENDS IN NEUROSCIENCES

Microglia mechanics: immune activation alters traction forces and durotaxis

(2015) Lars Bollmann et al.   Frontiers in Cellular Neuroscience

Microglial cell dysregulation in brain aging and neurodegeneration

(2015) Rommy von Bernhardi et al.   Frontiers in Aging Neuroscience

Direct Interaction of Kindlin-3 With Integrin αIIbβ3 in Platelets Is Required for Supporting Arterial Thrombosis in Mice

(2014) Zhen Xu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The relationship between glial cell mechanosensitivity and foreign body reactions in the central nervous system

(2014) Pouria Moshayedi et al.   BIOMATERIALS

Transcriptional and Translational Regulation of TGF-  Production in Response to Apoptotic Cells

(2014) Y. Q. Xiao et al.   JOURNAL OF IMMUNOLOGY

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Microglial Dynamics and Role in the Healthy and Diseased Brain

(2014) Diego Gomez-Nicola et al.   NEUROSCIENTIST

Characterization of a Spontaneous Retinal Neovascular Mouse Model

(2014) Eiichi Hasegawa et al.   PLoS One

Bipolar/rod-shaped microglia are proliferating microglia with distinct M1/M2 phenotypes

(2014) Wing Yip Tam et al.   Scientific Reports

Plasticity of primary microglia on micropatterned geometries and spontaneous long-distance migration in microfluidic channels

(2013) Susanna Amadio et al.   BMC NEUROSCIENCE

The mechanical control of nervous system development

(2013) K. Franze   DEVELOPMENT

LRG1 promotes angiogenesis by modulating endothelial TGF-β signalling

(2013) Xiaomeng Wang et al.   NATURE

DNA targeting specificity of RNA-guided Cas9 nucleases

(2013) Patrick D Hsu et al.   NATURE BIOTECHNOLOGY

Epigenome-wide differences in pathology-free regions of multiple sclerosis–affected brains

(2013) Jimmy L Huynh et al.   NATURE NEUROSCIENCE

Identification of a unique TGF-β–dependent molecular and functional signature in microglia

(2013) Oleg Butovsky et al.   NATURE NEUROSCIENCE

Microglia are the major source of TNF-α and TGF-β1 in postnatal glial cultures; regulation by cytokines, lipopolysaccharide, and vitronectin

(2013) Jennifer V. Welser-Alves et al.   NEUROCHEMISTRY INTERNATIONAL

Rod-Like Microglia Are Restricted to Eyes with Laser-Induced Ocular Hypertension but Absent from the Microglial Changes in the Contralateral Untreated Eye

(2013) Rosa de Hoz et al.   PLoS One

PGC-1α Regulates Normal and Pathological Angiogenesis in the Retina

(2012) Magali Saint-Geniez et al.   AMERICAN JOURNAL OF PATHOLOGY

Eyeing central neurons in vascular growth and reparative angiogenesis

(2012) P. Sapieha   BLOOD

Integrin signaling in vascular function

(2012) Nikolay L. Malinin et al.   CURRENT OPINION IN HEMATOLOGY

Novel aspects of Kindlin-3 function in humans based on a new case of leukocyte adhesion deficiency III

(2012) J. MELLER et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Age-related macular degeneration

(2012) Laurence S Lim et al.   LANCET

Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner

(2012) Dorothy P. Schafer et al.   NEURON

NCBI GEO: archive for functional genomics data sets—update

(2012) Tanya Barrett et al.   NUCLEIC ACIDS RESEARCH

Demyelination reduces brain parenchymal stiffness quantified in vivo by magnetic resonance elastography

(2012) K. Schregel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Use the force: membrane tension as an organizer of cell shape and motility

(2012) Alba Diz-Muñoz et al.   TRENDS IN CELL BIOLOGY

Decreased brain stiffness in Alzheimer's disease determined by magnetic resonance elastography

(2011) Matthew C. Murphy et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Regulation of angiogenesis by a non-canonical Wnt–Flt1 pathway in myeloid cells

(2011) James A. Stefater III et al.   NATURE

TGF-β Signaling Specifies Axons during Brain Development

(2010) Jason J. Yi et al.   CELL

Cytoskeletal coherence requires myosin-IIA contractility

(2010) Y. Cai et al.   JOURNAL OF CELL SCIENCE

Dendritic cells are early responders to retinal injury

(2010) Ute Lehmann et al.   NEUROBIOLOGY OF DISEASE

Tissue architecture and function: dynamic reciprocity via extra- and intra-cellular matrices

(2009) Ren Xu et al.   CANCER AND METASTASIS REVIEWS

M-CSF inhibition selectively targets pathological angiogenesis and lymphangiogenesis

(2009) Yoshiaki Kubota et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A point mutation in KINDLIN3 ablates activation of three integrin subfamilies in humans

(2009) Nikolay L Malinin et al.   NATURE MEDICINE

TGF-β Is Required for Vascular Barrier Function, Endothelial Survival and Homeostasis of the Adult Microvasculature

(2009) Tony E. Walshe et al.   PLoS One

Rapid leukocyte migration by integrin-independent flowing and squeezing

(2008) Tim Lämmermann et al.   NATURE

Two Faces of Chondroitin Sulfate Proteoglycan in Spinal Cord Repair: A Role in Microglia/Macrophage Activation

(2008) Asya Rolls et al.   PLOS MEDICINE

CNS injury, glial scars, and inflammation: Inhibitory extracellular matrices and regeneration failure

(2007) Michael T. Fitch et al.   EXPERIMENTAL NEUROLOGY