Article
Medicine, General & Internal
Johnson Chia-Shen Yang, Yu-Ming Wang, Shao-Chun Wu, Wei-Che Lin, Peng-Chen Chien, Pei-Yu Tsai, Ching-Hua Hsieh, Sheng-Dean Luo
Summary: This study investigates the impact of age on the effectiveness of lymphaticovenous anastomosis (LVA) in older patients. The results show that LVA can provide relief for secondary lower limb lymphedema (LLL) in older patients with favorable lymphatic vessel characteristics.
JOURNAL OF CLINICAL MEDICINE
(2022)
Editorial Material
Surgery
Marco Innocenti, Gerardo Malzone, Giulio Menichini
Summary: Microsurgery has become standard care for complex techniques, and robotic assistance has potential for extreme motion scaling and tremor reduction. The Symani Surgical System was used to successfully complete a robot-assisted microsurgical free flap reconstruction, demonstrating feasibility for anastomosis of small vessels. The system has the potential to open up new opportunities in microsurgery.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2023)
Article
Biology
Tom J. M. van Mulken, Shan S. Qiu, Yasmine Jonis, Jairo J. A. Profar, Taco J. Blokhuis, Jan Geurts, Rutger M. Schols, Rene R. W. J. van der Hulst
Summary: Innovative techniques can overcome the limitations of the human body in microsurgery. High-definition 3D cameras can replace conventional operation microscopes to improve ergonomics for surgeons, while a dedicated robot for microsurgery can enhance the precision and stability of their hands. The integration of both technologies has been demonstrated in the first-in-human case of reconstructive microsurgery.
Article
Multidisciplinary Sciences
Gerardo Malzone, Giulio Menichini, Marco Innocenti, Alberto Ballestin
Summary: Technical advances in microsurgery have enabled complex oncological reconstructions, but manual abilities can be affected by human fatigue and tremor. Robotic assistance has the potential to overcome these issues and improve clinical outcomes. This in-vivo preclinical study using a rat model found that robotic and manual techniques for anastomoses were equivalent in terms of vessel patency, but robotic anastomosis had a longer execution time and slightly decreased tissue damage according to histological analysis.
SCIENTIFIC REPORTS
(2023)
Article
Rehabilitation
Riikka Lampinen, Jeannette Q. Lee, Janella Leano, Christine Miaskowski, Judy Mastick, Lisa Brinker, Kimberly Topp, Betty Smoot
Summary: In this study comparing negative pressure massage treatment (NPMT) with manual lymphatic drainage (MLD) in women with chronic breast cancer-related lymphedema, NPMT demonstrated greater improvements in lymphedema index and limb volume compared to MLD. However, differences in Disabilities of the Arm, Shoulder, and Hand questionnaire scores were not statistically significant.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2021)
Article
Critical Care Medicine
Mario G. Santamarina, Ignacio Beddings, Felipe Martinez Lomakin, Dominique Boisier Riscal, Monica Gutierrez Claveria, Jaime Vidal Marambio, Nicole Retamal Baez, Cristian Pavez Novoa, Cesar Reyes Allende, Paulina Ferreira Perey, Miguel Gutierrez Torres, Camila Villalobos Mazza, Constanza Vergara Sagredo, Sebastian Ahumada Bermejo, Eduardo Labarca Mellado, Elizabeth Barthel Munchmeyer, Solange Marchant Ramos, Mariano Volpacchio, Jorge Vega
Summary: Oral sildenafil treatment may have potential therapeutic effects in COVID-19 patients regarding the need for invasive mechanical ventilation (IMV) in specific perfusion patterns observed in sCTA. However, there were no significant differences in oxygenation parameters. Larger-scale studies are needed to confirm these findings.
Article
Surgery
Benedikt Schaefer, Joerg Bahm, Justus P. Beier
Summary: The demands for microsurgical techniques in peripheral nerve surgery are increasing as multiple simultaneous selective nerve transfers are used, including the transposition of very small nerves and single fascicles. Robot technology, the Symani Surgical System (Medical Microinstruments, S.p.A, Calci, Pisa, Italy), was successfully used for microsurgical coaptation of very small nerve structures, providing precise and accurate sutures. This new microsurgical robotic system opens possibilities for finer and more complex nerve transfers in difficult-to-reach anatomical regions.
PLASTIC AND RECONSTRUCTIVE SURGERY-GLOBAL OPEN
(2023)
Article
Surgery
Benedikt Schaefer, Joerg Bahm, Justus P. P. Beier
Summary: The microsurgical demands in peripheral nerve surgery are increasing, requiring high skills in microsurgical techniques. Robot technology, combined with a high-magnification 3D-exoscope, allows for successful coaptation of very small nerve structures. This opens new possibilities for carrying out finer and more complex nerve transfers, even in difficult-to-reach anatomical regions.
PLASTIC AND RECONSTRUCTIVE SURGERY-GLOBAL OPEN
(2023)
Article
Psychology, Multidisciplinary
Eman A. Elhosary, Hamada Ahmed Hamada, Fatimah Ali AlMubali, Guillermo Lopez F. Sanchez, Sara M. Ahmed
Summary: The study evaluates the effectiveness of 448 kHz monopolar capacitive resistive radiofrequency (MCRR) in the treatment of stress urinary incontinence (SUI) in females. The results show that the combination of MCRR therapy and pelvic floor exercises significantly reduces symptom frequency, improves pelvic floor muscle strength, and has better effects compared to placebo treatment.
FRONTIERS IN PSYCHOLOGY
(2023)
Article
Clinical Neurology
Virendra R. Desai, Jonathan J. Lee, Trevis Sample, Neal S. Kleiman, Alan Lumsden, Gavin W. Britz
Summary: The study presented the first human experience of robotic-assisted neurovascular intervention in the extracranial carotid circulation, showing that incorporating robotic technology in neurovascular intervention can enhance procedural technique and reduce occupational hazards, with no technical complications and no need for conversion to manual neurovascular intervention.
Article
Urology & Nephrology
Nisha Bansal, David Glidden, Rajnish Mehrotra, Raymond R. Townsend, Jordana Cohen, Lori Linke, Farshad Palad, Hannah Larson, Chi-yuan Hsu
Summary: This pilot trial aimed to test the feasibility of treating home versus predialysis blood pressure in hemodialysis patients. The study demonstrated high adherence to home blood pressure measurement and treatment, but also showed some adverse reactions such as increased frequency of fatigue in the home blood pressure arm. Further larger trials should be conducted to assess the long-term feasibility, efficacy, and safety of home blood pressure treatment in hemodialysis patients.
AMERICAN JOURNAL OF KIDNEY DISEASES
(2021)
Article
Surgery
Justus P. Beier, Stephan Hackenberg, Anja M. Boos, Ali Modabber, Thien An Duong Dinh, Frank Hoelzle
Summary: Robotic microsurgery is a novel technology for microsurgical free flap transplantation, and its potential benefits and drawbacks need to be evaluated for broader future application. In this first free flap series using a robotic system, a total of 23 flaps were performed with the system, showing the feasibility of robot-assisted anastomoses in different clinical conditions and subspecialties.
PLASTIC AND RECONSTRUCTIVE SURGERY-GLOBAL OPEN
(2023)
Article
Orthopedics
Jianhua Hu, Feng Chen, Guixing Qiu, Tiansheng Sun, Huilin Yang, Huiyong Shen, Peijian Tong, Yimin Chai, Xueli Zhang, Weibin Zhang, Zhidong Yang, Hong Jiang, Yalin Pan, Tianliang Zhu, Chengjian He, Weiping Xiao
Summary: The study demonstrated the efficacy of Jingshu Keli in treating cervical spondylotic radiculopathy by significantly reducing pain scores in patients. This marks the first randomized, double-blind trial confirming the clinical efficacy and safety of Jingshu Keli for this condition.
JOURNAL OF ORTHOPAEDIC TRANSLATION
(2021)
Article
Oncology
Shirin M. Shallwani, Anna Towers, Anne Newman, Shannon Salvador, Angela Yung, Lucy Gilbert, Walter H. Gotlieb, Xing Zeng, Doneal Thomas
Summary: Research trials exploring lymphedema risk-reduction strategies in women with gynecological cancer are feasible but challenging. A tailored intervention of compression and exercise is safe and feasible in this population, and may delay the onset of lymphedema. Further research is needed to determine the role of these strategies in reducing the risk of lymphedema for women with gynecological cancer.
Article
Medicine, General & Internal
Irene Aprile, Carmela Conte, Arianna Cruciani, Cristiano Pecchioli, Letizia Castelli, Sabina Insalaco, Marco Germanotta, Chiara Iacovelli
Summary: The use of robotic technology in the rehabilitation of stroke patients has shown positive results. Comprehensive training of gait and trunk using robotic rehabilitation therapy can improve balance ability and lower limb muscle strength in subacute stroke patients.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Ophthalmology
Suryan Dunker, Bjorn Winkens, Frank van den Biggelaar, Rudy Nuijts, Pieter Jan Kruit, Mor Dickman
Summary: This Dutch registry study identified risk factors for rebubbling and early graft failure in DMEK. Rebubbling was associated with higher graft failure, while older recipient age and surgical complications were risk factors for rebubbling. Early graft failure risk factors included transplantation before 2016 and surgical complications. Rebubbling was also associated with significantly lower endothelial cell densities.
BRITISH JOURNAL OF OPHTHALMOLOGY
(2023)
Article
Surgery
Jamilla L. M. Wederfoort, Esther van Santbrink, Juliette E. Hommes, Esther M. Heuts, Sander M. J. Van Kuijk, Rene R. W. J. van der Hulst, Andrzej Piatkowski
Summary: This study aimed to evaluate donor site satisfaction following autologous fat transfer (AFT) for total breast reconstruction in breast cancer patients. The results showed no significant difference in body satisfaction between AFT and implant-based reconstruction, indicating that large-volume liposuction does not aesthetically affect the utilized donor sites. However, reconstructive surgeons should be aware of possible donor site complications, especially contour irregularities at the thighs, and discuss this with their patients.
AESTHETIC SURGERY JOURNAL
(2023)
Article
Medicine, General & Internal
M. M. Suverein, T. S. R. Delnoij, R. Lorusso, G. J. Brandon Bravo Bruinsma, L. Otterspoor, C. V. Elzo Kraemer, A. P. J. Vlaar, J. J. van der Heijden, E. Scholten, C. den Uil, T. Jansen, B. van den Bogaard, M. Kuijpers, K. Y. Lam, J. M. Montero Cabezas, A. H. G. Driessen, S. Z. H. Rittersma, B. G. Heijnen, D. Dos Reis Miranda, G. Bleeker, J. de Metz, R. S. Hermanides, J. Lopez Matta, S. Eberl, D. W. Donker, R. J. van Thiel, S. Akin, O. van Meer, J. Henriques, K. C. Bokhoven, L. Mandigers, J. J. H. Bunge, M. E. Bol, B. Winkens, B. Essers, P. W. Weerwind, J. G. Maessen, M. C. G. van de Poll
Summary: Extracorporeal cardiopulmonary resuscitation (CPR) and conventional CPR have similar effects on survival with a favorable neurologic outcome in patients with refractory out-of-hospital cardiac arrest.
NEW ENGLAND JOURNAL OF MEDICINE
(2023)
Article
Neurosciences
Elske Gravesteijn, Jos J. Adam, Ronald P. Mensink, Bjorn Winkens, Jogchum Plat
Summary: This study found that NWT-03 egg protein hydrolysate can improve cognitive function in patients with metabolic syndrome, especially in the executive function domain. The specific mechanism of action needs further research.
NUTRITIONAL NEUROSCIENCE
(2023)
Article
Sport Sciences
Yingyi Wu, Pascal W. M. Van Gerven, Renate H. M. de Groot, Bert O. O. Eijnde, Bjorn Winkens, Hans H. C. M. Savelberg
Summary: University students often engage in prolonged sitting, which negatively affects their cognition and mood. Light-intensity physical activity (LIPA) breaks may improve attention and executive functioning. However, interrupting sitting with LIPA did not have significant acute effects on attention, response inhibition, working memory updating, or mood.
SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS
(2023)
Article
Surgery
Alexander Gabriel Saelmans, Maud Rijkx, Juliette Hommes, Rene van der Hulst, Andrzej Piatkowski
Summary: In general, total breast reconstruction with autologous fat transfer has a low complication rate. However, infections remain a common complication. This case report presents a severe bilateral breast infection following the surgery, which was successfully treated with surgery and antibiotics. Early surgical prophylaxis and antibiotic treatment can reduce the incidence of breast infections, and identifying and managing infection risks can be improved through monitoring the fit of devices and implementing video consultations.
INTERNATIONAL JOURNAL OF SURGERY CASE REPORTS
(2023)
Review
Oncology
Anouk A. S. van den Bosch, Johanna M. A. Pijnenborg, Andrea Romano, Bjorn Winkens, Louis J. M. van der Putten, Roy F. P. M. Kruitwagen, Henrica M. J. Werner
Summary: This systematic review found that adipose tissue (AT) distribution plays a significant role in the development and prognosis of endometrial cancer (EC), correlating with obesity measures, histological subtypes, lymph node metastasis, and sex steroid levels. Further well-designed prospective studies are needed to explore these differences more specifically and understand how it can contribute to the prediction and therapy of EC.
FRONTIERS IN ONCOLOGY
(2023)
Article
Gastroenterology & Hepatology
L. M. Janssen, A. Rezazadeh Ardabili, M. J. L. Romberg-Camps, B. Winkens, R. J. van den Broek, J. Hulst, H. J. A. Verwijs, D. Keszthelyi, D. M. A. E. Jonkers, A. A. van Bodegraven, M. J. Pierik, Z. Mujagic
Summary: Abdominal pain is common in patients with IBD in remission and is associated with psychosocial factors. A more holistic treatment approach for patients with IBD suffering from abdominal pain may improve quality of care and subjective wellbeing.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2023)
Article
Nutrition & Dietetics
Marla T. H. Hahnraths, Bjorn Winkens, Onno C. P. van Schayck
Summary: Understanding the health effects of scaled-up school-based interventions is crucial for integrating health in schools. This study examined the effectiveness of the Healthy Primary School of the Future (HPSF) initiative in real-world settings. Due to COVID-19 limitations, implementation of HPSF activities was restricted. Results showed that waist circumference in the medium implementer group significantly increased at one-year and two-year follow-up compared to the low implementer group. No significant effects were observed for other outcomes.
Article
Oncology
Monse W. M. Wieland, Walmari Pilz, Bjorn Winkens, Ann Hoeben, Anna C. H. Willemsen, Bernd Kremer, Laura W. J. Baijens
Summary: Oropharyngeal dysphagia, malnutrition, sarcopenia, and frailty are common risks in newly diagnosed head-and-neck cancer patients. Early identification through multi-domain screening can help prevent complications and improve treatment outcomes.
Article
Surgery
J. L. M. Wederfoort, N. Voeten, N. N. P. M. Smeins, J. E. Hommes, B. A. B. Essers, R. R. W. J. van der Hulst, BREAST-Trial Investigators
Summary: This study investigates the cost-effectiveness of autologous fat transfer (AFT) versus implant-based reconstruction (IBR) in breast reconstruction. The results show that AFT has higher quality-adjusted life years (QALY) and costs in the first year postoperative. However, due to the absence of additional surgeries, AFT is estimated to be more cost-effective over the 10- and 30-year period.
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
(2023)
Meeting Abstract
Gastroenterology & Hepatology
N. Bevers, A. Aliu, D. Wong, L. Derijks, B. Winkens, A. Vreugdenhil, M. Pierik, P. Van Rheenen
JOURNAL OF CROHNS & COLITIS
(2023)
Article
Endocrinology & Metabolism
Kelly G. H. van de Pas, Maartje A. P. de Krom, Bjorn Winkens, Francois M. H. van Dielen, Anita C. E. Vreugdenhil
Summary: This study aimed to evaluate the health-related quality of life (HRQoL) in treatment-seeking children and adolescents with overweight, obesity, and severe obesity. The results showed that individuals with severe obesity had significantly lower physical and psychological wellbeing compared to those with overweight and obesity. It is important for lifestyle intervention programs to consider the specific needs of this vulnerable group.
Meeting Abstract
Gastroenterology & Hepatology
J. Snijkers, B. Winkens, L. Vork, Z. Z. Weerts, Z. Mujagic, C. Leue, J. Kruimel, D. Jonkers, A. Masclee, D. Keszthelyi
NEUROGASTROENTEROLOGY AND MOTILITY
(2023)
Article
Geriatrics & Gerontology
Anne G. R. Visser, Bjorn Winkens, Jos M. G. A. Schols, Rob Janknegt, Bartholomeus Spaetgens
Summary: This study assessed the impact of polypharmacy on 30-day COVID-related mortality in nursing home residents. The results showed that nursing home residents with a higher number of medications and who were not vaccinated had a higher 30-day COVID-related mortality. These findings have important implications for managing COVID-19 in the frail nursing home population.
EUROPEAN GERIATRIC MEDICINE
(2023)
