Combined burden and functional impact tests for cancer driver discovery using DriverPower
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Combined burden and functional impact tests for cancer driver discovery using DriverPower
Authors
Keywords
-
Journal
Nature Communications
Volume 11, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-02-06
DOI
10.1038/s41467-019-13929-1
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Analyses of non-coding somatic drivers in 2,658 cancer whole genomes
- (2020) Esther Rheinbay et al. NATURE
- Genomic basis for RNA alterations in cancer
- (2020) Claudia Calabrese et al. NATURE
- Pan-cancer analysis of whole genomes
- (2020) NATURE
- Patterns of somatic structural variation in human cancer genomes
- (2020) Yilong Li et al. NATURE
- Cancer genomics: Less is more in the hunt for driver mutations
- (2017) Sushant Kumar et al. NATURE
- Recurrent and functional regulatory mutations in breast cancer
- (2017) Esther Rheinbay et al. NATURE
- Fast, scalable prediction of deleterious noncoding variants from functional and population genomic data
- (2017) Yi-Fei Huang et al. NATURE GENETICS
- Discovery of Cancer Driver Long Noncoding RNAs across 1112 Tumour Genomes: New Candidates and Distinguishing Features
- (2017) Andrés Lanzós et al. Scientific Reports
- Non-coding cancer driver candidates identified with a sample- and position-specific model of the somatic mutation rate
- (2017) Malene Juul et al. eLife
- Nucleotide excision repair is impaired by binding of transcription factors to DNA
- (2016) Radhakrishnan Sabarinathan et al. NATURE
- Differential DNA repair underlies mutation hotspots at active promoters in cancer genomes
- (2016) Dilmi Perera et al. NATURE
- A spectral approach integrating functional genomic annotations for coding and noncoding variants
- (2016) Iuliana Ionita-Laza et al. NATURE GENETICS
- Role of non-coding sequence variants in cancer
- (2016) Ekta Khurana et al. NATURE REVIEWS GENETICS
- Toward a Shared Vision for Cancer Genomic Data
- (2016) Robert L. Grossman et al. NEW ENGLAND JOURNAL OF MEDICINE
- The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas
- (2016) D. Fang et al. SCIENCE
- MOF Acetylates the Histone Demethylase LSD1 to Suppress Epithelial-to-Mesenchymal Transition
- (2016) Huacheng Luo et al. Cell Reports
- Expression of hMOF, but not HDAC4, is responsible for the global histone H4K16 acetylation in gastric carcinoma
- (2015) LIN ZHU et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Highly recurrent mutations of SGK1, DUSP2 and JUNB in nodular lymphocyte predominant Hodgkin lymphoma
- (2015) S Hartmann et al. LEUKEMIA
- Integrative analysis of 111 reference human epigenomes
- (2015) Anshul Kundaje et al. NATURE
- Cell-of-origin chromatin organization shapes the mutational landscape of cancer
- (2015) Paz Polak et al. NATURE
- Identification of significantly mutated regions across cancer types highlights a rich landscape of functional molecular alterations
- (2015) Carlos L Araya et al. NATURE GENETICS
- LARVA: an integrative framework for large-scale analysis of recurrent variants in noncoding annotations
- (2015) Lucas Lochovsky et al. NUCLEIC ACIDS RESEARCH
- Somatic mutation in cancer and normal cells
- (2015) I. Martincorena et al. SCIENCE
- MEF2B mutations in non-Hodgkin lymphoma dysregulate cell migration by decreasing MEF2B target gene activation
- (2015) Julia R. Pon et al. Nature Communications
- DANN: a deep learning approach for annotating the pathogenicity of genetic variants
- (2014) Daniel Quang et al. BIOINFORMATICS
- GPR126 Protein Regulates Developmental and Pathological Angiogenesis through Modulation of VEGFR2 Receptor Signaling
- (2014) Hengxiang Cui et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A general framework for estimating the relative pathogenicity of human genetic variants
- (2014) Martin Kircher et al. NATURE GENETICS
- COSMIC: exploring the world's knowledge of somatic mutations in human cancer
- (2014) Simon A. Forbes et al. NUCLEIC ACIDS RESEARCH
- The UCSC Genome Browser database: 2015 update
- (2014) Kate R. Rosenbloom et al. NUCLEIC ACIDS RESEARCH
- An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic element
- (2014) M. R. Mansour et al. SCIENCE
- Lessons from the Cancer Genome
- (2013) Levi A. Garraway et al. CELL
- SRSF1 and SRSF9 RNA binding proteins promote Wnt signalling-mediated tumorigenesis by enhancing β-catenin biosynthesis
- (2013) Yu Fu et al. EMBO Molecular Medicine
- Mutational heterogeneity in cancer and the search for new cancer-associated genes
- (2013) Michael S. Lawrence et al. NATURE
- Increasing the complexity of chromatin: functionally distinct roles for replication-dependent histone H2A isoforms in cell proliferation and carcinogenesis
- (2013) R. Singh et al. NUCLEIC ACIDS RESEARCH
- Genetic heterogeneity of diffuse large B-cell lymphoma
- (2013) Jenny Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Impact of deleterious passenger mutations on cancer progression
- (2013) C. D. McFarland et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Highly Recurrent TERT Promoter Mutations in Human Melanoma
- (2013) F. W. Huang et al. SCIENCE
- Cancer Genome Landscapes
- (2013) B. Vogelstein et al. SCIENCE
- GENCODE: The reference human genome annotation for The ENCODE Project
- (2012) J. Harrow et al. GENOME RESEARCH
- Chromatin organization is a major influence on regional mutation rates in human cancer cells
- (2012) Benjamin Schuster-Böckler et al. NATURE
- Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
- (2012) Jeremy Schwartzentruber et al. NATURE
- Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas
- (2012) Gang Wu et al. NATURE GENETICS
- ENCODE Data in the UCSC Genome Browser: year 5 update
- (2012) Kate R. Rosenbloom et al. NUCLEIC ACIDS RESEARCH
- Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing
- (2012) J. G. Lohr et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- BigWig and BigBed: enabling browsing of large distributed datasets
- (2010) W. J. Kent et al. BIOINFORMATICS
- BEDTools: a flexible suite of utilities for comparing genomic features
- (2010) Aaron R. Quinlan et al. BIOINFORMATICS
- Stability selection
- (2010) Nicolai Meinshausen et al. JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY
- International network of cancer genome projects
- (2010) Thomas J. Hudson (Chairperson) et al. NATURE
- The cancer genome
- (2009) Michael R. Stratton et al. NATURE
- Validation of an LC-MS based approach for profiling histones in chronic lymphocytic leukemia
- (2009) Xiaodan Su et al. PROTEOMICS
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started