Reduced H3K27me3 leads to abnormal Hox gene expression in neural tube defects

Elevated H3K79 homocysteinylation causes abnormal gene expression during neural development and subsequent neural tube defects

(2018) Qin Zhang et al.   Nature Communications

Folate deficiency facilitates recruitment of upstream binding factor to hot spots of DNA double-strand breaks of rRNA genes and promotes its transcription

(2016) Qiu Xie et al.   NUCLEIC ACIDS RESEARCH

DNA methylation analysis of Homeobox genes implicatesHOXB7hypomethylation as risk factor for neural tube defects

(2015) Anne Rochtus et al.   Epigenetics

The E3 ubiquitin ligase activity of RING1B is not essential for early mouse development

(2015) Robert S. Illingworth et al.   GENES & DEVELOPMENT

Abnormal epigenetic regulation of the gene expression levels of Wnt2b and Wnt7b: Implications for neural tube defects

(2015) BAOLING BAI et al.   Molecular Medicine Reports

Genetic, Epigenetic, and Environmental Contributions to Neural Tube Closure

(2014) Jonathan J. Wilde et al.   Annual Review of Genetics

Geminin loss causes neural tube defects through disrupted progenitor specification and neuronal differentiation

(2014) Ethan S. Patterson et al.   DEVELOPMENTAL BIOLOGY

The regulation of Hox gene expression during animal development

(2013) Moisés Mallo et al.   DEVELOPMENT

Histone modification mapping in human brain reveals aberrant expression of histone H3 lysine 79 dimethylation in neural tube defects

(2013) Qin Zhang et al.   NEUROBIOLOGY OF DISEASE

The Immediate Early Gene Product EGR1 and Polycomb Group Proteins Interact in Epigenetic Programming during Chondrogenesis

(2013) Frank Spaapen et al.   PLoS One

Additional Sex Combs-Like 2 Is Required for Polycomb Repressive Complex 2 Binding at Select Targets

(2013) Hsiao-Lei Lai et al.   PLoS One

The Continuing Challenge of Understanding, Preventing, and Treating Neural Tube Defects

(2013) J. B. Wallingford et al.   SCIENCE

A Genetic Approach to the Recruitment of PRC2 at the HoxD Locus

(2013) Patrick Schorderet et al.   PLoS Genetics

USF1 and hSET1A Mediated Epigenetic Modifications Regulate Lineage Differentiation and HoxB4 Transcription

(2013) Changwang Deng et al.   PLoS Genetics

Ash1l Methylates Lys36 of Histone H3 Independently of Transcriptional Elongation to Counteract Polycomb Silencing

(2013) Hitomi Miyazaki et al.   PLoS Genetics

APRIL stimulates NF-κB-mediated HoxC4 induction for AID expression in mouse B cells

(2012) Seok-Rae Park et al.   CYTOKINE

Hydroxylation of 5-methylcytosine by TET2 maintains the active state of the mammalian HOXA cluster

(2012) Michael T. Bocker et al.   Nature Communications

MicroRNA gene expression signatures in the developing neural tube

(2011) Partha Mukhopadhyay et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Enforced expression of the transcription factor HOXD3 under the control of the Wnt1 regulatory element modulates cell adhesion properties in the developing mouse neural tube

(2011) Yasushi Taniguchi et al.   JOURNAL OF ANATOMY

Relation between hypomethylation of long interspersed nucleotide elements and risk of neural tube defects

(2010) Li Wang et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Epigenetic control of Hox genes during neurogenesis, development, and disease

(2010) Benjamin A. Barber et al.   ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER

An update to the list of mouse mutants with neural tube closure defects and advances toward a complete genetic perspective of neural tube closure

(2010) Muriel J. Harris et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Epigenomic Reorganization of the Clustered Hox Genes in Embryonic Stem Cells Induced by Retinoic Acid

(2010) Vasundhra Kashyap et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Global Control of Motor Neuron Topography Mediated by the Repressive Actions of a Single Hox Gene

(2010) Heekyung Jung et al.   NEURON

Retinoic Acid Synthesis and Signaling during Early Organogenesis

(2008) Gregg Duester   CELL

All-trans-retinoic acid alters Smads expression in embryonic neural tissue of mice

(2008) Juntao Zhang et al.   JOURNAL OF APPLIED TOXICOLOGY

Mapping and quantifying mammalian transcriptomes by RNA-Seq

(2008) Ali Mortazavi et al.   NATURE METHODS