Pharmacological enhancement of TFEB-mediated autophagy alleviated neuronal death in oxidative stress-induced Parkinson’s disease models

Alpha-lipoic acid alleviated 6-OHDA-induced cell damage by inhibiting AMPK/mTOR mediated autophagy

(2019) Lina Zhou et al.   NEUROPHARMACOLOGY

Chloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusion

(2018) Mario Mauthe et al.   Autophagy

Experimental design and analysis and their reporting II: updated and simplified guidance for authors and peer reviewers

(2018) Michael J Curtis et al.   BRITISH JOURNAL OF PHARMACOLOGY

6-Hydroxydopamine induces autophagic flux dysfunction by impairing transcription factor EB activation and lysosomal function in dopaminergic neurons and SH-SY5Y cells

(2018) Xin He et al.   TOXICOLOGY LETTERS

Therapeutic potential of autophagy-enhancing agents in Parkinson’s disease

(2017) Tim E. Moors et al.   Molecular Neurodegeneration

Baicalein prevents 6-OHDA/ascorbic acid-induced calcium-dependent dopaminergic neuronal cell death

(2017) Sheng-Fang Wang et al.   Scientific Reports

A novel curcumin analog binds to and activates TFEB in vitro and in vivo independent of MTOR inhibition

(2016) Ju-Xian Song et al.   Autophagy

Activated cathepsin L is associated with the switch from autophagy to apoptotic death of SH-SY5Y cells exposed to 6-hydroxydopamine

(2016) Lingyun Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

MCOLN1 is a ROS sensor in lysosomes that regulates autophagy

(2016) Xiaoli Zhang et al.   Nature Communications

Mitochondrial outer-membrane E3 ligase MUL1 ubiquitinates ULK1 and regulates selenite-induced mitophagy

(2015) Jie Li et al.   Autophagy

Autophagy in acute leukemias: A double-edged sword with important therapeutic implications

(2015) Cecilia Evangelisti et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

ROS and Autophagy: Interactions and Molecular Regulatory Mechanisms

(2015) Lulu Li et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

β-asarone and levodopa co-administration protects against 6-hydroxydopamine-induced damage in parkinsonian rat mesencephalon by regulating autophagy: down-expression Beclin-1 and light chain 3B and up-expression P62

(2015) Li-Ping Huang et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Insights into the importance for designing curcumin-inspired anticancer agents by a prooxidant strategy: The case of diarylpentanoids

(2015) Fang Dai et al.   FREE RADICAL BIOLOGY AND MEDICINE

Targeting α-synuclein for treatment of Parkinson's disease: mechanistic and therapeutic considerations

(2015) Benjamin Dehay et al.   LANCET NEUROLOGY

Inhibition of Mitochondrial Clearance and Cu/Zn-SOD Activity Enhance 6-Hydroxydopamine-Induced Neuronal Apoptosis

(2015) Sua In et al.   MOLECULAR NEUROBIOLOGY

Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB

(2015) Diego L. Medina et al.   NATURE CELL BIOLOGY

Endoplasmic reticulum stress induced by tunicamycin and thapsigargin protects against transient ischemic brain injury

(2014) Xiangnan Zhang et al.   Autophagy

Rapamycin attenuates mitochondrial dysfunction via activation of mitophagy in experimental ischemic stroke

(2014) Qiang Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and Parkin

(2014) Ghazaleh Ashrafi et al.   JOURNAL OF CELL BIOLOGY

Enhancing Astrocytic Lysosome Biogenesis Facilitates A  Clearance and Attenuates Amyloid Plaque Pathogenesis

(2014) Q. Xiao et al.   JOURNAL OF NEUROSCIENCE

Autophagy: a double-edged sword for neuronal survival after cerebral ischemia

(2014) Kangyong Liu et al.   Neural Regeneration Research

Hypoxia-induced autophagy in endothelial cells: a double-edged sword in the progression of infantile haemangioma?

(2013) Gang Chen et al.   CARDIOVASCULAR RESEARCH

Human iPSC-Based Modeling of Late-Onset Disease via Progerin-Induced Aging

(2013) Justine D. Miller et al.   Cell Stem Cell

Generating a Non-Integrating Human Induced Pluripotent Stem Cell Bank from Urine-Derived Cells

(2013) Yanting Xue et al.   PLoS One

TFEB-mediated autophagy rescues midbrain dopamine neurons from  -synuclein toxicity

(2013) M. Decressac et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Efficient and Rapid Derivation of Primitive Neural Stem Cells and Generation of Brain Subtype Neurons From Human Pluripotent Stem Cells

(2013) Yiping Yan et al.   Stem Cells Translational Medicine

Autophagy in lysosomal storage disorders

(2012) Andrew P. Lieberman et al.   Autophagy

PGC-1  Rescues Huntington's Disease Proteotoxicity by Preventing Oxidative Stress and Promoting TFEB Function

(2012) T. Tsunemi et al.   Science Translational Medicine

An ATP-competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1

(2009) Carson C. Thoreen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Gene Network Regulating Lysosomal Biogenesis and Function

(2009) Marco Sardiello et al.   SCIENCE

Autophagy: A lysosomal degradation pathway with a central role in health and disease

(2008) Eeva-Liisa Eskelinen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The role of autophagy-lysosome pathway in neurodegeneration associated with Parkinson's disease

(2008) T. Pan et al.   BRAIN

6-Hydroxydopamine (6-OHDA) induces Drp1-dependent mitochondrial fragmentation in SH-SY5Y cells

(2008) Maria Gomez-Lazaro et al.   FREE RADICAL BIOLOGY AND MEDICINE