A20 targets PFKL and glycolysis to inhibit the progression of hepatocellular carcinoma

A20 prevents inflammasome-dependent arthritis by inhibiting macrophage necroptosis through its ZnF7 ubiquitin-binding domain

(2019) Apostolos Polykratis et al.   NATURE CELL BIOLOGY

Transcriptional Regulation of the Warburg Effect in Cancer by SIX1

(2018) Ling Li et al.   CANCER CELL

miR-200a enhances TRAIL-induced apoptosis in gastric cancer cells by targeting A20

(2018) Tianshu Guo et al.   CELL BIOLOGY INTERNATIONAL

TNFα induces tolerant production of CXC chemokines in colorectal cancer HCT116 cells via A20 inhibition of ERK signaling

(2018) Xin Zhou et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

TAp73-induced phosphofructokinase-1 transcription promotes the Warburg effect and enhances cell proliferation

(2018) Le Li et al.   Nature Communications

Identification of a multienzyme complex for glucose metabolism in living cells

(2017) Casey L. Kohnhorst et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A20 promotes metastasis of aggressive basal-like breast cancers through multi-monoubiquitylation of Snail1

(2017) Ji-Hyung Lee et al.   NATURE CELL BIOLOGY

Stabilization of phosphofructokinase 1 platelet isoform by AKT promotes tumorigenesis

(2017) Jong-Ho Lee et al.   Nature Communications

Tumor-specific expression of shVEGF and suicide gene as a novel strategy for esophageal cancer therapy

(2016) Ting Liu et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression

(2015) Chih-Hao Chang et al.   CELL

A20 suppresses hepatocellular carcinoma proliferation and metastasis through inhibition of Twist1 expression

(2015) Haiyang Chen et al.   Molecular Cancer

IAPP-driven metabolic reprogramming induces regression of p53-deficient tumours in vivo

(2014) Avinashnarayan Venkatanarayan et al.   NATURE

Zinc finger A20 and NF-κB correlate with high-risk human papillomavirus of squamous cell carcinoma patients

(2014) Ya-Juan Tang et al.   TUMOR BIOLOGY

Bladder Polypoid Cystitis-Derived A20 Associates with Tumorigenesis

(2013) Ming Wang et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Identification of stromal differentially expressed proteins in the colon carcinoma by quantitative proteomics

(2013) Yibing Mu et al.   ELECTROPHORESIS

Constitutive activation of distinct NF-κB signals in EBV-associated nasopharyngeal carcinoma

(2013) Grace Tin-Yun Chung et al.   JOURNAL OF PATHOLOGY

Brain tumor initiating cells adapt to restricted nutrition through preferential glucose uptake

(2013) William A Flavahan et al.   NATURE NEUROSCIENCE

A20 in inflammation and autoimmunity

(2013) Leen Catrysse et al.   TRENDS IN IMMUNOLOGY

Expression of A20 is reduced in pancreatic cancer tissues

(2012) Qing Wang et al.   JOURNAL OF MOLECULAR HISTOLOGY

A20 Ubiquitin Ligase–Mediated Polyubiquitination of RIP1 Inhibits Caspase-8 Cleavage and TRAIL-Induced Apoptosis in Glioblastoma

(2012) Anita C. Bellail et al.   Cancer Discovery

Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation

(2011) Sophia Y. Lunt et al.   Annual Review of Cell and Developmental Biology

Acetylation Regulates Gluconeogenesis by Promoting PEPCK1 Degradation via Recruiting the UBR5 Ubiquitin Ligase

(2011) Wenqing Jiang et al.   MOLECULAR CELL

Ubiquitylation in apoptosis: a post-translational modification at the edge of life and death

(2011) Domagoj Vucic et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Quantitative proteomic analysis identifying three annexins as lymph node metastasis-related proteins in lung adenocarcinoma

(2010) Ying-Fu Liu et al.   MEDICAL ONCOLOGY

TNFAIP3/A20 functions as a novel tumor suppressor gene in several subtypes of non-Hodgkin lymphomas

(2009) K. Honma et al.   BLOOD

Identificating 14-3-3 sigma as a lymph node metastasis-related protein in human lung squamous carcinoma

(2009) Dan-juan Li et al.   CANCER LETTERS

A20 protects mice from lethal liver ischemia/reperfusion injury by increasing peroxisome proliferator-activated receptor-α expression

(2009) Haley E. Ramsey et al.   LIVER TRANSPLANTATION

Proteomic analysis of the stroma-related proteins in nasopharyngeal carcinoma and normal nasopharyngeal epithelial tissues

(2009) Mei-xiang Li et al.   MEDICAL ONCOLOGY

Frequent inactivation of A20 in B-cell lymphomas

(2009) Motohiro Kato et al.   NATURE

Targeting the ubiquitin system in cancer therapy

(2009) Daniela Hoeller et al.   NATURE

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

A20: Central Gatekeeper in Inflammation and Immunity

(2008) Beatrice Coornaert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Basis for the Unique Deubiquitinating Activity of the NF-κB Inhibitor A20

(2007) Su-Chang Lin et al.   JOURNAL OF MOLECULAR BIOLOGY