Review
Oncology
Kevin P. Labadie, Laleh G. Melstrom, Aaron G. Lewis
Summary: This review discusses the key factors in developing a minimally invasive hepatopancreatobiliary (MIS HPB) program and shares our recent experience in adopting and expanding a minimally invasive approach to pancreaticoduodenectomy.
JOURNAL OF SURGICAL ONCOLOGY
(2023)
Review
Surgery
Ahmad Ozair, Amelia Collings, Alexandra M. Adams, Rebecca Dirks, Bradley S. Kushner, Iswanto Sucandy, David Morrell, Ahmed M. Abou-Setta, Timothy Vreeland, Jake Whiteside, Jordan M. Cloyd, Mohammed T. Ansari, Sean P. Cleary, Eugene Ceppa, William Richardson, Adnan Alseidi, Ziad Awad, Subhashini Ayloo, Joseph F. Buell, Georgios Orthopoulos, Samer Sbayi, Go Wakabayashi, Bethany J. Slater, Aurora Pryor, D. Rohan Jeyarajah
Summary: MIS and open hepatectomy show similar oncologic outcomes for treating colorectal liver metastases, but MIS has a shorter length of hospital stay, lower blood loss, and lower complication rate, regardless of staged or simultaneous resections.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Review
Endocrinology & Metabolism
Lisa H. de Vries, Dilay Aykan, Lutske Lodewijk, Johanna A. A. Damen, Inne H. M. Borel Rinkes, Menno R. Vriens
Summary: A systematic review and meta-analysis compared eight commonly used minimally invasive thyroid surgeries individually with standard of care, showing no significant differences in complications or length of hospital stay between minimally invasive techniques and conventional thyroidectomy.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Review
Surgery
Wardah Rafaqat, Tashfeen Ahmad, Muhammad Talal Ibrahim, Sudhesh Kumar, Eric M. Bluman, Khalid S. Khan
Summary: This study compared the complications of minimally invasive surgery (MIS) and open procedures for orthopedic spinal, upper limb, and lower limb surgeries. The results showed that MIS had fewer total, postoperative, and intraoperative complications in spinal procedures, but there was no significant safety advantage in upper limb and lower limb procedures compared to open procedures.
INTERNATIONAL JOURNAL OF SURGERY
(2022)
Article
Surgery
Robert J. Torphy, Chloe Friedman, Alison L. Halpern, Steven A. Ahrendt, Martin D. McCarter, Marco Del Chiaro, Richard D. Schulick, Ana Gleisner
Summary: This study evaluated the mortality associated with the implementation of minimally invasive pancreaticoduodenectomy (MIPD) using the National Cancer Database. The results showed a decrease in 90-day mortality with increased cumulative MIPD volume, as well as a protective effect of annual open pancreaticoduodenectomy (PD) volume on mortality.
JOURNAL OF SURGICAL RESEARCH
(2021)
Review
Medicine, General & Internal
Florin Graur, Razvan Alexandru Ciocan, Andra Ciocan, Ion Cosmin Puia, Emil Mois, Luminita Furcea, Florin Zaharie, Calin Popa, Diana Schlanger, Calin Vaida, Doina Pisla, Nadim Al Hajjar
Summary: This study analyzed the application of SILS and NOTES in liver surgery. The results showed that transvaginal liver resection is feasible and safe, and the goals of SILS and NOTES are to be less intrusive, more easily tolerated, and aesthetic.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Clinical Neurology
Elliot H. Choi, Alvin Y. Chan, Andrew D. Gong, Zachary Hsu, Andrew K. Chan, Joshua N. Limbo, John D. Hong, Nolan J. Brown, Brian V. Lien, Jordan Davies, Nihal Satyadev, Nischal Acharya, Chen Yi Yang, Yu-Po Lee, Kiarash Golshani, Nitin N. Bhatia, Frank P. K. Hsu, Michael Y. Oh
Summary: This study found no significant difference in operative outcomes between total and subtotal resection for spinal tumors, but patients undergoing total resection showed slightly better improvement in neurological function compared to those undergoing subtotal resection. Overall, both total and subtotal resection may result in comparable outcomes for patients with spinal tumors, with maximal safe resection being the ideal treatment to provide the greatest chance of long-term benefit.
WORLD NEUROSURGERY
(2021)
Review
Surgery
Lang Chen, Ning Xia, Zihe Wang, Junjie Xiong, Bole Tian
Summary: This study conducted a systematic review and meta-analysis on the safety and effectiveness of minimally invasive total pancreatectomy (MITP) compared to open total pancreatectomy (OTP). The results indicated that MITP had lower major morbidity, less blood loss, and a lower intraoperative transfusion rate compared to OTP. Further research with better design is needed to confirm these findings.
INTERNATIONAL JOURNAL OF SURGERY
(2023)
Review
Surgery
Samir Pathak, Barry G. Main, Natalie S. Blencowe, Jonathan R. E. Rees, Harry F. Robertson, Reyad A. G. Abbadi, Jane M. Blazeby
Summary: The study aimed to analyze the surgical technique, governance procedures, and outcome reporting of MITTLR. Findings revealed that while some literature clearly stated patient selection criteria, most did not fully describe the technical details; some papers reported ethical approval, but did not mention measures to mitigate harm; technical outcomes commonly reported were blood loss, operative time, and margin status.
Review
Oncology
Winifred M. M. Lo, Samer T. T. Tohme, David A. A. Geller
Summary: Minimally invasive surgery, including laparoscopic and robotic approaches, is a safe and effective option for treating liver metastases from colorectal cancer. Laparoscopic liver resection (LLR) is associated with shorter hospital stays and similar post-operative complications compared to open techniques. LLR allows for early initiation of chemotherapy and simultaneous resection of colorectal and liver tumors can be safe in selected patients. Robotic liver resection (RLR) has comparable safety and may improve resection rates. It is important to carefully select patients and ensure surgeon experience when considering minimally invasive liver surgery for colorectal liver metastases.
Article
Oncology
Jony van Hilst, Nine de Graaf, Mohammad Abu Hilal, Marc G. Besselink
Summary: Minimally invasive pancreatic surgeries are becoming more common, but further research is needed to evaluate their safety and efficacy, especially in pancreatoduodenectomy. Studies have shown advantages of minimally invasive distal pancreatectomy in terms of shorter hospital stay and less intraoperative blood loss, while minimally invasive pancreatoduodenectomy does not present clear superiority over open approaches.
ANNALS OF SURGICAL ONCOLOGY
(2021)
Review
Gastroenterology & Hepatology
Mamoru Morimoto, Federico Tomassini, Giammauro Berardi, Yasuhisa Mori, Chikara Shirata, Mohammed Abu Hilal, Horacio J. Asbun, Daniel Cherqui, Naoto Gotohda, Ho-Seong Han, Yutaro Kato, Fernando Rotellar, Atsushi Sugioka, Masakazu Yamamoto, Go Wakabayashi
Summary: The Glissonean approach has been widely used in MIALR with reported advantages such as shorter operative time, lower blood loss and better peri-operative outcomes. However, clear understanding of Laennec's capsule anatomy is required and the best surgical approach depends on surgeon experience and patient characteristics.
JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES
(2022)
Review
Oncology
Francisca dos S. Coelho, Diana E. Barros, Filipa A. Santos, Flavia C. Meireles, Francisca C. Maia, Rita A. Trovisco, Teresa M. Machado, Jose A. Barbosa
Summary: The paradigm of esophageal cancer treatment has shifted towards minimally invasive esophagectomy (MIE) over open esophagectomy (OE), with MIE showing trends towards decreased 30-day and 90-day postoperative mortality and fewer major cardiovascular and respiratory complications. Minor postoperative complications may also be reduced with MIE.
Article
Surgery
Dawn Jung, Hassaan Bari, Ho Kyoung Hwang, Woo Jung Lee, Chang Moo Kang
Summary: This study compares the short-term and long-term outcomes of minimally invasive central pancreatectomy (MI-CP) and minimally invasive spleen-preserving subtotal distal pancreatectomy (MI-SpSTDP). It found that MI-CP is safe and effective in preserving endocrine and exocrine functions in the treatment of benign or borderline tumors located at the neck or proximal body of the pancreas.
ASIAN JOURNAL OF SURGERY
(2023)
Review
Gastroenterology & Hepatology
Francesco Lancellotti, Diego Coletta, Nicola de'Liguori Carino, Thomas Satyadas, Santhalingam Jegatheeswaran, Martina Maruccio, Aali J. Sheen, Ajith K. Siriwardena, Saurabh Jamdar
Summary: This study compares the risk of venous thromboembolism (VTE) after open liver resection (OLR) and minimally invasive liver resection (MILR). The findings indicate that patients who underwent OLR have a higher incidence of VTE, including deep venous thrombosis and pulmonary embolism, compared to those who underwent MILR.
Article
Surgery
Maarten Korrel, Sanne Lof, Bilal Al Sarireh, Bergthor Bjornsson, Ugo Boggi, Giovanni Butturini, Riccardo Casadei, Matteo De Pastena, Alessandro Esposito, Jean Michel Fabre, Giovanni Ferrari, Fadhel Samir Fteriche, Giuseppe Fusai, Bas Groot Koerkamp, Thilo Hackert, Mathieu D'Hondt, Asif Jah, Tobias Keck, Marco Marino, I. Quintus Molenaar, Patrick Pessaux, Andrea Pietrabissa, Edoardo Rosso, Mushegh Sahakyan, Zahir Soonawalla, Francois Regis Souche, Steve White, Alessandro Zerbi, Safi Dokmak, Bjorn Edwin, Mohammad Abu Hilal, Marc Besselink
Summary: This study compared short-term clinical outcomes after Kimura and Warshaw spleen-sparing minimally invasive distal pancreatectomy (MIDP). The rates of secondary splenectomy and major complications did not differ significantly between Kimura and Warshaw MIDP. Kimura MIDP was associated with longer operative time and less blood loss compared to Warshaw MIDP.
Article
Surgery
Leonard W. F. Seelen, Anne Floortje van Oosten, Lilly J. H. Brada, Vincent P. Groot, Lois A. Daamen, Marieke S. Walma, Bastiaan F. van der Lek, Mike S. L. Liem, Gijs A. Patijn, Martijn W. J. Stommel, Ronald M. van Dam, Bas Groot Koerkamp, Olivier R. Busch, Ignace H. J. T. de Hingh, Casper H. J. van Eijck, Marc G. Besselink, Richard A. Burkhart, Inne H. M. Borel Rinkes, Christopher L. Wolfgang, Izaak Quintus Molenaar, Jin He, Hjalmar C. van Santvoort
Summary: The objective of this study was to establish a evidence-based cutoff and predictors for early recurrence in patients with resected locally advanced pancreatic cancer (LAPC). After analyzing long-term follow-up data, a cutoff time of 6 months was determined to differentiate between early and late recurrence, and early recurrence was associated with poor survival. Preoperative predictors included post-induction therapy carbohydrate antigen (CA) 19-9 level, tumor differentiation and postoperative predictors included poor tumor differentiation and lack of adjuvant chemotherapy. These findings are valuable for guiding and counseling patients with LAPC before and after resection.
Article
Surgery
Simone Augustinus, Anouk E. J. A. Latenstein, Bert R. Bonsing, Olivier Busch, Bas Groot Koerkamp, Ignace H. J. T. E. de Hingh, Vincent de Meijer, I. Quintus C. Molenaar, Hjalmar van Santvoort, Judith H. de Vos-Geelen, Casper G. van Eijck, Marc Besselink, Dutch Pancreatic Canc Grp
Summary: This study aimed to assess the clinical impact and risk factors of chyle leak (CL) after pancreatoduodenectomy. The nationwide Dutch Pancreatic Cancer Audit was used to include consecutive patients from all 19 centers. The rate of CL was 7.0% and it was associated with prolonged hospital stay. Vascular resection and open surgery were identified as predictors of CL.
Article
Oncology
Jacob K. K. de Bakker, J. Annelie Suurmeijer, Jurgen G. J. Toennaer, Bert A. A. Bonsing, Olivier R. R. Busch, Casper H. H. van Eijck, Ignace H. H. de Hingh, Vincent E. E. de Meijer, I. Quintus Molenaar, Hjalmar C. C. van Santvoort, Martijn W. W. Stommel, Sebastiaan Festen, Erwin van der Harst, Gijs Patijn, Daan J. J. Lips, Marcel Den Dulk, Koop Bosscha, Marc G. G. Besselink, Geert Kazemier
Summary: Pancreatoduodenectomy for duodenal adenocarcinoma is associated with higher rates of major complications, pancreatic fistula, re-interventions, and in-hospital mortality compared with patients undergoing pancreatoduodenectomy for other cancers.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Oncology
Jelle C. van Dongen, Eva Versteijne, Bert A. Bonsing, J. Sven D. Mieog, Ignace H. J. T. de Hingh, Sebastiaan Festen, Gijs A. Patijn, Ronald van Dam, Erwin van der Harst, Jan H. Wijsman, Koop Bosscha, Marion van der Kolk, Vincent E. de Meijer, Mike S. L. Liem, Olivier R. Busch, Marc G. H. Besselink, Geertjan van Tienhoven, Bas Groot Koerkamp, Casper H. J. van Eijck, Mustafa Suker
Summary: This study aimed to evaluate the value of staging laparoscopy in detecting occult metastases in patients with resectable or borderline resectable pancreatic cancer. The results showed that staging laparoscopy could detect occult metastases in about 10% of patients, and these patients were more likely to receive palliative systemic chemotherapy.
Article
Gastroenterology & Hepatology
Nadine C. M. van Huijgevoort, Sanne A. M. Hoogenboom, Selma J. Lekkerkerker, Olivier R. Busch, Marco Del Chiaro, Paul Fockens, Inne Somers, Joanne Verheij, Rogier P. Voermans, Marc G. Besselink, Jeanin E. van Hooft
Summary: Background: Follow-up in patients with intraductal papillary mucinous neoplasm (IPMN) aims to detect advanced neoplasia (high-grade dysplasia/cancer) in an early stage. The 2015 American Gastroentero-logical Association (AGA), 2017 International Association of Pancreatology (IAP), and the 2018 European Study Group on Cystic tumours of the Pancreas (European) guidelines differ in their recommendations on indications for surgery. However, it remains unclear which guideline is most accurate in predicting advanced neoplasia in IPMN. Methods: Patients who underwent surgery were extracted from a prospective database (January 2006-January 2021). In patients with IPMN, final pathology was compared with the indication for surgery according to the guidelines. ROC-curves were calculated to determine the diagnostic accuracy for each guideline. Results: Overall, 247 patients underwent surgery for cystic lesions. In 145 patients with IPMN, 52 had advanced neoplasia, of which the AGA guideline would have advised surgery in 14 (27%), the IAP and European guideline in 49 (94%) and 50 (96%). In 93 patients without advanced neoplasia, the AGA, IAP, and European guidelines would incorrectly have advised surgery in 8 (8.6%), 77 (83%) and 71 (76%). Conclusion: The European and IAP guidelines are clearly superior in detecting advanced neoplasia in IPMN as compared to the AGA, albeit at the cost of a higher rate of unnecessary surgery. To harmonize care and to avoid confusion caused by conflicting statements, a global evidence-based guideline for PCN in collaboration with the various guidelines groups is required once the current guidelines require an update. (c) 2023 Published by Elsevier B.V. on behalf of IAP and EPC.
Letter
Oncology
Tess M. E. W. van Ramshorst, Jeffrey W. Chen, Mohammad G. Abu Hilal, Marc G. Besselink
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Oncology
Nynke Michiels, Deesje Doppenberg, Jesse V. Groen, Eran van Veldhuisen, Bert A. Bonsing, Olivier R. Busch, A. Stijn L. P. Crobach, Otto M. van Delden, Susan van Dieren, Arantza Farina, Ignace H. J. T. de Hingh, Rob Hurks, Joost Nederend, Shirin Shahbazi Feshtali, Yeliz Tank, A. L. Vahrmeijer, Martin Wasser, Marc G. Besselink, J. Sven D. Mieog
Summary: Intraoperative ultrasound (IOUS) can provide real-time additional information during surgery for pancreatic cancer with vascular involvement, and it has been found to change the resectability status in over one-third of patients, facilitating progress during surgical exploration. This finding should be confirmed by larger studies.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Editorial Material
Oncology
Simone Augustinus, Pascale J. M. V. Schafrat, Boris A. Janssen, Bert Bonsing, Lodewijk A. A. R. Brosens, Olivier Busch, Stijn Crobach, Michail H. Doukas, Casper van Eijck, Lydia G. M. van der Geest, Bas Groot Koerkamp, Ignace H. J. T. de Hingh, G. Mihaela C. Raicu, Hjalmar van Santvoort, Marie-Louise van Velthuysen, Joanne G. Verheij, Marc Besselink, Arantza Farina Sarasqueta
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Surgery
Tess M. E. van Ramshorst, Bjorn Edwin, Ho-Seong Han, Masafumi Nakamura, Yoo-Seok Yoon, Takao Ohtsuka, Tore Tholfsen, Marc G. Besselink, Mohammad Abu Hilal
Summary: This study compared the learning curves and outcomes of laparoscopic distal pancreatectomy (LDP) between self-taught and trained surgeons. The learning curves of trained surgeons were at least halved compared to self-taught surgeons, with lower operative time and complication rates.
INTERNATIONAL JOURNAL OF SURGERY
(2023)
Review
Oncology
Simone Augustinus, Gajanan Thurairajah, Marc G. Besselink, Hanneke W. M. van Laarhoven, Martijn G. H. van Oijen, Tara M. Mackay, Johanna W. Wilmink
Summary: Due to increased use of imaging, more advanced stages of cancer are being diagnosed in an early, asymptomatic phase. The optimal timing of chemotherapy in asymptomatic patients with advanced cancer is still uncertain, and there is a lack of systematic reviews on this topic.
Article
Surgery
Sanne Lof, Linda Claassen, Gerjon Hannink, Bilal Al-Sarireh, Bergthor Bjornsson, Ugo Boggi, Fernando Burdio, Giovanni Butturini, Giovanni Capretti, Riccardo Casadei, Safi Dokmak, Bjorn Edwin, Alessandro Esposito, Jean M. Fabre, Giovanni Ferrari, Asmund A. Fretland, Fadhel S. Fteriche, Giuseppe K. Fusai, Alessandro Giardino, Bas Groot Koerkamp, Mathieu D'Hondt, Asif Jah, Sivesh K. Kamarajah, Emanuele F. Kauffmann, Tobias Keck, Stijn van Laarhoven, Alberto Manzoni, Marco V. Marino, Ravi Marudanayagam, Izaak Q. Molenaar, Patrick Pessaux, Edoardo Rosso, Roberto Salvia, Zahir Soonawalla, Regis Souche, Steven White, Frans van Workum, Alessandro Zerbi, Camiel Rosman, Martijn W. J. Stommel, Mohammed Abu Hilal, Marc G. Besselink
Summary: Understanding the learning curve of MIDP is important in reducing patient harm. This multicenter study analyzed data from 26 European centers to evaluate the length of the learning curve. The findings suggest that 85 procedures are needed to achieve optimal outcomes, while earlier mastery can be achieved for conversion rate, operation time, and intraoperative blood loss.
Correction
Surgery
Michelle R. de Graaff, Rianne N. M. Hogenbirk, Yester F. Janssen, Arthur K. E. Elfrink, Ronald S. L. Liem, Simon W. Nienhuijs, Jean Paul P. M. de Vries, Jan Willem Elshof, Emiel Verdaasdonk, Jarno Melenhorst, H. L. van Westreenen, Marc G. H. Besselink, Jelle P. Ruurda, Mark I. van Berge Henegouwen, Joost M. Klaase, Marcel den Dulk, Mark van Heijl, Johannes H. Hegeman, Jerry Braun, Daan M. Voeten, Franka S. Wurdemann, Anne Loes K. Warps, Anna J. Alberga, J. Annelie Suurmeijer, Erman O. Akpinar, Nienke Wouters, Anne Loes van den Boom, Marieke J. Bolster-van Eenennaam, Peter van Duijvendijk, David J. Heineman, Michel W. J. M. Wouters, Schelto Kruijff
BRITISH JOURNAL OF SURGERY
(2023)
Article
Surgery
Deesje Doppenberg, Jacob L. van Dam, Youngmin Han, Bert A. Bonsing, Olivier R. Busch, Sebastiaan Festen, Erwin van der Harst, Ignace H. de Hingh, Marjolein Y. Homs, Wooil Kwon, Mirang Lee, Daan J. Lips, Vincent E. de Meijer, I. Quintus Molenaar, Joost J. Nuyttens, Gijs A. Patijn, Stijn van Roessel, George P. van der Schelling, Mustafa Suker, Eva Versteijne, Judith de Vos-Geelen, Johanna W. Wilmink, Casper H. J. van Eijck, Geertjan van Tienhoven, Jin-Young Jang, Marc G. Besselink, Bas Groot Koerkamp
Summary: Two randomized controlled trials (RCTs) have shown that neoadjuvant chemoradiotherapy (CRT) is associated with better survival in patients with resectable and borderline resectable pancreatic cancers compared to upfront surgery. The baseline serum CA19-9 level does not affect the treatment effect of neoadjuvant CRT, indicating that it should not be withheld based on CA19-9 concentration.
BRITISH JOURNAL OF SURGERY
(2023)
Review
Surgery
Aagje J. M. Pronk, Anne Roelofs, David R. Flum, H. Jaap Bonjer, Mohammed Abu Hilal, Marcel G. W. Dijkgraaf, Marc G. Besselink, Usama Ahmed Ali
Summary: This systematic review analyzed 1188 surgical randomized controlled trials (RCTs) from three different years (1999, 2009, and 2019) and found that the global volume of published surgical RCTs remained stable in the past decade, but the proportion of RCTs with low risk of bias increased from 14.7% to 22.1%. Asia saw an increase in surgical RCTs, while Europe saw a decrease.
BRITISH JOURNAL OF SURGERY
(2023)
