Article
Medicine, General & Internal
Maria Costantino, Carmine Sellitto, Valeria Conti, Graziamaria Corbi, Francesco Marongiu, Giovanni Genovese, Giuseppina Moccia, Mario Capunzo, Anna Borrelli, Pasquale Pagliano, Mario Farroni, Grazia Maria Lombardi, Maria Giovanna Elberti, Amelia Filippelli, Francesco De Caro
Summary: This observational study reports potential adverse events following immunization with two different COVID-19 vaccines, AZD1222 and BNT162b2. The study found a higher incidence of adverse events in the AZD-vac group compared to the BNT-vac group. Fever was the most frequent adverse event associated with AZD1222, while pain at the injection site was most frequent with BNT162b2. The study also found a higher incidence of adverse events in women after receiving the BNT162b2 vaccine.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Immunology
Miguel Garcia-Grimshaw, Santa Elizabeth Ceballos-Liceaga, Anaclara Michel-Chavez, Mario Garcia-Alanis, Arturo Cadena-Fernandez, Javier Andres Galnares-Olalde, Guillermo Carbajal-Sandoval, Daniel Amado Carrillo-Garcia, Noe Hernandez-Valdivia, Laura E. Hernandez-Vanegas, Maria del Mar Saniger-Alba, Alonso Gutierrez-Romero, Jose Luis Diaz-Ortega, Gustavo Reyes-Teran, Hugo Lopez-Gatell, Fernando Daniel Flores-Silva, Carlos Cantu-Brito, Erwin Chiquete, Antonio Arauz, Sergio Ivan Valdes-Ferrer
Summary: mRNA-based COVID-19 vaccines are effective, but persistent vaccine hesitancy is partly due to a misperception of their potential adverse events. This study described the anatomy and associated factors of developing NSSS among BNT162b2 recipients, suggesting that the benign nature of these symptoms may help dissipate hesitation towards this vaccine.
Article
Immunology
Ene Gbenewei, Terna Nomhwange, Lydia Taiwo, Isiaka Ayodeji, Kabir Yusuf, Anne E. Jean Baptiste, Peter Nsubuga, Fiona Braka, Joseph Oteri, Faisal Shuaib
Summary: This article discusses Nigeria's experience with AEFI reporting during the 2017/2018 Measles vaccination campaign, identifying 6,214 suspected cases with a majority being non-serious and resolving fully with no long-term sequalae. Adequate reporting, investigation, and management are essential in managing the risk of disruptions in mass vaccination campaigns.Deployment of supervisors during campaigns and real-time follow-up by national operations teams play crucial roles in improving the identification and reporting of suspected AEFIs and in decision-making and intervention.
Article
Multidisciplinary Sciences
Metha Apiwattanakul, Narupat Suanprasert, Arada Rojana-Udomsart, Thanes Termglinchan, Chaichana Sinthuwong, Tasanee Tantirittisak, Suchat Hanchaiphiboolkul, Pantep Angchaisuksiri, Suphot Srimahachota, Jurai Wongsawat, Somjit Stiudomkajorn, Sasisopin Kiertiburanakul, Chonnamet Techasaensiri, Wannada Laisuan, Weerawat Manosuthi, Pawinee Doungngern, Wereyarmarst Jaroenkunathum, Teeranart Jivapaisarnpong, Apinya Panjangampatthana, Jirapa Chimmanee, Kulkanya Chokephaibulkit
Summary: This study describes the clinical characteristics of immunization stress-related responses causing stroke-like events following COVID-19 vaccination in Thailand. The majority of patients were women, and those receiving CoronaVac were younger. The symptoms developed shortly after vaccination, and sensory symptoms were the most common. Most patients had a good outcome.
Article
Biotechnology & Applied Microbiology
Xuejiao Pan, Huakun Lv, Fuxing Chen, Ying Wang, Hui Liang, Linzhi Shen, Yaping Chen, Yu Hu
Summary: This study summarized passive surveillance data for adverse events following immunization in Zhejiang province, showing that AEFI mainly occurred among infants under 1 year old, with majority of reported cases not serious. The findings suggest the continuous use of national AEFI surveillance system as a monitoring tool.
HUMAN VACCINES & IMMUNOTHERAPEUTICS
(2021)
Article
Medicine, General & Internal
Minji Jeon, Jehun Kim, Chi Eun Oh, Jin-Young Lee
Summary: The study focused on investigating adverse events following immunization (AEFIs) for COVID-19 among healthcare workers (HCWs) who received the ChAdOx1 nCoV-19 vaccine. The majority of AEFIs reported were mild-to-moderate in severity, with older age groups experiencing fewer and less severe AEFIs. No serious events requiring hospitalization were reported, and most AEFIs resolved within a few days. The use of the Mobile Vaccine Adverse Events Reporting System (MVAERS) was found to be helpful in monitoring and sharing accurate information about vaccination against COVID-19.
JOURNAL OF KOREAN MEDICAL SCIENCE
(2021)
Article
Immunology
Yunhua Wei, Yan Wang, Jian Liu, Yan Zha, Yuqi Yang, Ni Li, Yalin Zhou, Jinli Zhu, Neil Roberts, Lin Liu, Yaying Li
Summary: A comparative analysis was conducted to investigate the potential risk factors of Adverse Events Following Immunization (AEFI) after receiving different booster vaccines. The study found that doctors and women had a higher risk of adverse reactions, but overall, the rates of AEFI in all three booster groups were acceptable.
Review
Pediatrics
Manoja Kumar Das
Summary: Although vaccines undergo rigorous testing, concerns about their safety persist globally. Safety concerns related to measles, pentavalent, and HPV vaccines have significantly impacted vaccine coverage. Surveillance of adverse events following immunization (AEFI) faces challenges including reporting biases. Specialized studies are mandated to investigate adverse events of special interest (AESI) following vaccination. The exact pathophysiology of many AEFIs/AESIs remains unknown. Genetic factors, gender, age, and pro-inflammatory risk factors may contribute to AEFIs/AESIs. The uncertainty surrounding the frequency, profile, interval, and severity of AEFIs/AESIs, as well as variations across populations and the absence of definite markers, may create a black box effect for vaccines. Addressing these unanswered questions and effectively communicating with stakeholders is crucial to combat the anti-vaccine movement.
INDIAN JOURNAL OF PEDIATRICS
(2023)
Article
Behavioral Sciences
Hironobu Nakamura, Genichi Sugihara, Keiko Hara, Motoki Inaji, Masahiro Noha, Ichiro Takumi, Masako Watanabe, Hidehiko Takahashi, Taketoshi Maehara, Hitoshi Yamamoto, Shunsuke Takagi
Summary: This study reveals the stress and arousal characteristics in patients with epilepsy and their roles in mediating traits and state anxiety. These findings may reflect the long-term clinical course and unique emotion recognition tendencies in epilepsy.
EPILEPSY & BEHAVIOR
(2023)
Article
Immunology
Chayanit Mahasing, Oiythip Yasopa, Chalo Sansilapin, Thanit Rattanathumsakul, Panithee Thammawijaya, Rapeepong Suphanchaimat, Pawinee Doung-ngern
Summary: A cluster of individuals in an eastern province of Thailand experienced neurological symptoms after receiving COVID-19 vaccination. The investigation found a significant association between menstruation and immunization stress-related reactions (ISRR).
Article
Environmental Sciences
Arifa Sultana, Sabiha Rahman Mim, Ananya Saha, Fahmida Yesmin, Md. Rafat Tahsin, Nasiba Binte Bahar, Kazi Rubiya Fatema, Saimon Shahriar, Kazi Milenur Rahman Prattay, Fazle Rabbi, Fabiha Noushin, Mithun Samodder, Qurratul Ain Sadia, Jannatul Ferdous, Md. Ariful Haque Mamun, Mohammad Ikram Uddin, Tahmina Akter, Md. Mustafizur Rahman, Md. Moklesur Rahman Sarker, Md. Ruhul Kuddus, Fahima Aktar, Jakir Ahmed Chowdhury, Abu Asad Chowdhury, Shaila Kabir, Sultan Mehtap Bueyueker, Md. Sohanur Rahman, Md. Habibur Rahman, Md. Shah Amran
Summary: Mass vaccination programs have been effective in reducing the severity of the pandemic, but there have been reports of adverse effects in Turkey and Bangladesh. This study aimed to evaluate the adverse effects of different vaccines in both countries and the population's willingness to continue vaccination despite the side effects. An online survey was conducted from July to December 2021, and the questionnaire was shared with vaccinated individuals in Turkey and Bangladesh. The study found that a significant percentage of respondents experienced side effects, with pain at the injection site being the most common. However, there were no significant adverse events reported after receiving the COVID-19 vaccines in both countries. The vaccines showed similar patterns of efficacy and safety during the study period.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Psychiatry
Davy Vancampfort, Andreas Heissel, Aline Waclawovsky, Brendon Stubbs, Joseph Firth, Ryan L. McGrath, Tine Van Damme, Felipe B. Schuch
Summary: This meta-analysis examined the existence of true interindividual differences in the anxiolytic effects of exercise among adults with anxiety-and stress-related disorders. The results showed significant anxiolytic effects of both aerobic exercise and resistance training. However, there is currently a lack of convincing evidence to support the notion that true interindividual differences exist for the anxiolytic effects of exercise in this population. Therefore, clinical practice should focus on general population physical activity guidelines rather than highly specific, individualized recommendations.
PSYCHIATRY RESEARCH
(2022)
Article
Multidisciplinary Sciences
Lilla Nora Kovacs, Eva Katzinger, Sunghwan Yi, Zsolt Demetrovics, Aniko Maraz, Gyongyi Kokonyei
Summary: This study aimed to investigate the relationship between COVID-19-related distress and compulsive buying, and whether this relationship is mediated by task-focused and emotion-focused coping. The findings suggest that compulsive buying is more likely to occur as a result of emotion-focused coping in response to COVID-related distress, especially during periods of increasing distress.
Article
Biochemistry & Molecular Biology
Melissa N. Boucher, Victor May, Karen M. Braas, Sayamwong E. Hammack
Summary: PACAP is a pleiotropic polypeptide that activates G protein-coupled receptors and is widely distributed in the nervous system. It plays roles in regulating fear memories, anxiety-like behavior, and emotional pain. Outside of the CNS, PACAP may also participate in stress responses by modulating the HPA axis.
Article
Neurosciences
C. A. Favoretto, N. B. Bertagna, T. Righi, B. T. Rodolpho, A. Anjos-Santos, F. B. R. Silva, P. C. Bianchi, F. C. Cruz
Summary: The study evaluated the effects of chronic maternal separation (MS) on ethanol intake and striatal Fos expression induced by ethanol consumption. It also analyzed the impacts of MS on anxiety- and depressive-like behaviors, as well as locomotor and plasma corticosterone responses to ethanol treatment in adolescent mice. The results showed that MS transiently increased ethanol intake, but did not affect Fos expression, behavioral parameters, locomotor activity, or plasma corticosterone response.
NEUROSCIENCE LETTERS
(2023)
Review
Anesthesiology
Soeun Lee, Bruce D. Dick, Abbie Jordan, C. Meghan McMurtry
Summary: Parent interventions are important in supporting youth with chronic pain, showing potential benefits and feasibility. However, there is significant variability in study characteristics, treatment content, parent participation, and parent/youth outcomes in existing research.
CLINICAL JOURNAL OF PAIN
(2021)
Article
Psychiatry
Rachel M. Tomlinson, Kevin C. Bax, Dhandapani Ashok, C. Meghan McMurtry
Summary: The study found positive relations between positive psychological factors (optimism, pain self-efficacy) and health-related quality of life in youth with abdominal pain, suggesting the potential for further examination of these factors in intervention studies.
JOURNAL OF PSYCHOSOMATIC RESEARCH
(2021)
Article
Pediatrics
Hannah G. Gennis, Oana Bucsea, Shaylea D. Badovinac, Stefano Costa, C. Meghan McMurtry, David B. Flora, Rebecca Pillai Riddell
Summary: The study aimed to review and analyze the literature on the relationship between distress expression behaviors and distress regulation behaviors in infants and toddlers. The results showed that the second year of life had the strongest relationships, although there was substantial heterogeneity in the effects.
Article
Developmental Biology
Kaytlin L. Constantin, Rachel L. Moline, Rebecca Pillai Riddell, Jeffrey R. Spence, Chris M. Fiacconi, Kathryn Lupo-Flewelling, C. Meghan McMurtry
Summary: This study aimed to examine heart rate variability (HRV) during pediatric venipuncture and its association with mindfulness, parent anxiety, and catastrophizing. The findings showed that HRV differed throughout the procedure and practicing mindfulness did not consistently affect HRV. Positive synchrony in HRV was observed in dyads with high parental catastrophizing. The results contribute to our understanding of children's regulatory mechanisms.
DEVELOPMENTAL PSYCHOBIOLOGY
(2022)
Article
Psychology, Developmental
Kaytlin L. Constantin, Kathryn Lupo-Flewelling, Rachel L. Moline, C. Meghan McMurtry
Summary: Medical needle procedures can cause pain, distress, and fear in children. This study investigates how parent behaviors and children's internal emotion regulation, as measured by heart rate variability (HRV), are related to children's pain experiences. The findings suggest that children with lower HRV may experience higher distress and be more susceptible to parental reassurance, control, and empathy during needle procedures.
JOURNAL OF PEDIATRIC PSYCHOLOGY
(2023)
Article
Pediatrics
Kaytlin L. Constantin, Rachel L. Moline, Rebecca Pillai Riddell, Jeffrey R. Spence, C. Meghan McMurtry
Summary: Children's needle-related distress is strongly related to parental verbal behaviors. This study examined the contributors to parent verbal behaviors during pediatric venipuncture, including biological, psychological, and social factors. The results showed that child behaviors were strongly associated with parent behaviors, and baseline heart rate variability (HRV) moderated the association between parent catastrophizing and behavior. Social factors and parent's emotion regulation capacity played important roles in parent behaviors.
Article
Pediatrics
Melika Modabber, Karen M. Campbell, C. Meghan McMurtry, Anna Taddio, Laura J. Dempster
Summary: The study found that children emphasized four themes including establishing a therapeutic relationship, sharing power and responsibility, getting to know the person, and empowering the person, which are important for mitigating dental fear and anxiety. The study also found that children particularly value clinic staff attributes and communication skills, as well as the positive influence of pre-operative education and preparation.
Article
Pediatrics
Rachel L. Moline, Kaytlin Constantin, Christine T. T. Chambers, Deborah Powell, Stephen P. P. Lewis, Laryssa Laurignano, C. Meghan McMurtry
Summary: This study examined the effects of a mindfulness intervention on child pain and fear, as well as parent distress, during pediatric venipuncture procedures. The results showed that the intervention did not reduce child pain or fear but did reduce parent distress. Particularly, it was most helpful for parents who catastrophized about their child's pain.
Review
Pediatrics
Hiba Nauman, Olivia Dobson, Anna Taddio, Kathryn A. A. Birnie, C. Meghan McMurtry
Summary: This study summarizes picture books that focus on needle procedures for children aged 5-8 years old. All 48 books included at least one evidence-based coping strategy, but distressing aspects such as scary visuals and expressions of fear and pain were also present.
Article
Psychology, Developmental
Delane Linkiewich, Katherine C. Dib, Paula A. Forgeron, Bruce D. Dick, C. Meghan McMurtry
Summary: Adolescents with chronic pain face social challenges and desire peer support. This study fills a gap by focusing on their peer support needs.
JOURNAL OF PEDIATRIC PSYCHOLOGY
(2023)
Article
Psychology, Applied
Simonne J. Mastrella, Deborah M. Powell, Silvia Bonaccio, C. Meghan McMurtry
Summary: Interview anxiety is associated with lower interview performance ratings, and this study aimed to investigate the impact of interviewees' anxious nonverbal behavior on those ratings. The amount of interpersonal interaction in the job and interviewee gender were also examined as potential moderating factors. The results showed that participants in the high anxious nonverbal behavior condition gave lower interview performance ratings. However, job type and interviewee gender did not moderate this relationship. Therefore, interviewees' anxious nonverbal behavior may provide an explanation for the correlation between interview anxiety and lower performance ratings.
JOURNAL OF PERSONNEL PSYCHOLOGY
(2023)
Article
Medicine, Research & Experimental
Isabelle Fournier, Camille Caron, C. Meghan Mcmurtry, Annie Lapointe, Chantal Giguere, Marie-Joelle Dore-Bergeron, Mathieu Bergeron
Summary: This study compared the pain levels and outcomes between general anesthesia (GA) and local anesthesia (LA) in children undergoing tympanostomy tube insertion (TTI). The results showed that children experienced significantly less pain under GA compared to LA. Strategies to reduce pain and distress are important when using LA. There were no significant differences in the quality of life for patients and satisfaction of parents between the two anesthesia methods.
Article
Neurosciences
Nicole E. MacKenzie, Perri R. Tutelman, Christine T. Chambers, Jennifer A. Parker, Noni E. MacDonald, C. Meghan McMurtry, Pierre Pluye, Vera Granikov, Anna Taddio, Melanie Barwick, Kathryn A. Birnie, Katelynn E. Boerner
Summary: This study demonstrates the effectiveness of a KT tool that was relevant to parents' needs and built confidence to increase parent-reported uptake of evidence-based strategies. Proper pain management could positively impact parents' uptake of vaccinations for children.
Article
Clinical Neurology
Rachel L. Moline, C. Meghan McMurtry, Melanie Noel, Patrick J. McGrath, Christine T. Chambers
Summary: This study examined parent-child interactions during venipuncture and found that parent emotions and beliefs have an impact on the use of reassurance and distraction by parents. Results indicated that parent behaviors of reassurance and distraction can affect child pain outcomes, highlighting the importance of parental support during painful medical procedures.
CANADIAN JOURNAL OF PAIN-REVUE CANADIENNE DE LA DOULEUR
(2021)
Article
Multidisciplinary Sciences
Noni E. MacDonald, Jeannette Comeau, Eve Dube, Janice Graham, Margo Greenwood, Shawn Harmon, Janet McElhaney, C. Meghan McMurtry, Alan Middleton, Audrey Steenbeek, Anna Taddio
Summary: Acceptance of COVID-19 vaccines varies among different groups, influenced by a wide range of factors such as knowledge, attitudes, social networks, and cultural influences. To optimize vaccine acceptance, comprehensive strategies must be implemented considering all these factors to improve vaccination rates.
