Article
Engineering, Electrical & Electronic
Raffaele Gravina, Giancarlo Fortino
Summary: The term Body Sensor Network (BSN) was introduced less than twenty years ago, leading to rapid technical development and establishment of a rich interdisciplinary ecosystem. Despite previous challenges being addressed, new research opportunities arise from recent advances. The survey reviews the latest developments in BSN literature and explores advancements enabled by Edge computing, microelectronics, and communication innovation.
IEEE SENSORS JOURNAL
(2021)
Article
Computer Science, Information Systems
Will Carroll, Alana Turner, Purva Talegaonkar, Erin Parker, J. Carver Middleton, Preston Peranich, David Saucier, Reuben F. Burch, John E. Ball, Brian K. Smith, Harish Chander, Adam C. Knight, Charles E. Freeman
Summary: Soft robotic sensors are suitable for wearable technology, and this research evaluated the accuracy and repeatability of a newly-developed wearable prototype, demonstrating accurate joint angle estimation during complex, dynamic movements with minimal performance degradation even when wearing shoes over the sock prototype.
Article
Engineering, Electrical & Electronic
Jordan Tabor, Talha Agcayazi, Aaron Fleming, Brendan Thompson, Ashish Kapoor, Ming Liu, Michael Y. Lee, He Huang, Alper Bozkurt, Tushar K. Ghosh
Summary: Amputees often experience discomfort when wearing prosthetic devices, highlighting the need for new technologies to improve comfort. Textile-based sensors offer a promising solution for monitoring the inner socket environment, potentially enhancing comfort for amputees.
IEEE SENSORS JOURNAL
(2021)
Article
Engineering, Electrical & Electronic
Xueyang Liu, Chuanliang Li, Zhentao Wang, Yifeng Li, Jianqiu Huang, Huiyang Yu
Summary: This paper presents flexible pressure sensors based on 3D printing technology, with a sandwich structure design and a hollow prism structure pressure sensitive layer. Experimental synthesis of three kinds of flexible composite dielectrics demonstrated that the sensor with PDMS doping both BaTiO3 and CNTs showed the highest sensitivity, 1.3 times that of the reference sensor, indicating that fabricating composite dielectrics in this way has the potential to improve device performance.
IEEE SENSORS JOURNAL
(2021)
Article
Engineering, Electrical & Electronic
Yuliang Zhao, Xiaoliang Meng, Xianshou Ren, Chao Lian, Jiaheng Sun, Xiaopeng Sha, Shuyu Wang, Lianjiang Li, Wen Jung Li
Summary: The study introduces an effective gymnastics motion recognition and evaluation system using a sensor network and LDA algorithm to achieve high accuracy in motion recognition and evaluation, balancing both accuracy and portability.
IEEE SENSORS JOURNAL
(2021)
Article
Engineering, Electrical & Electronic
Yu Gu, Yi Han, Xiangzhi Liu, Ning Zhang, Xiufeng Zhang, Min Pan, Shuoyu Wang, Wei Dong, Tao Liu
Summary: This article proposes a three-stage real-time adaptive anti-disturbance data fusion algorithm to improve the measurement accuracy of MIMU-flexible sensor-based wearable systems under magnetic disturbance. The performance of the algorithm is validated on a designed wearable system, and the results show high accuracy in the indoor environment.
IEEE SENSORS JOURNAL
(2023)
Review
Chemistry, Analytical
Subhas Chandra Mukhopadhyay, Nagender Kumar Suryadevara, Anindya Nag
Summary: This paper provides a comprehensive review of the deployment of wearable sensors in healthcare applications, including their fabrication, integration, performance comparison, and challenges. The paper also presents the combination of sensing prototypes with the Internet of Things (IoT) for fully functioning sensorized systems.
Review
Engineering, Electrical & Electronic
Giuseppe D'Aniello, Raffaele Gravina, Matteo Gaeta, Giancarlo Fortino
Summary: In the past fifteen years, wearable sensorized devices have been widely used in various domains, but there is still a lack of research, models, methods, and theoretical foundations for situation-aware wearable systems. This article provides a survey and classification of state-of-the-art situation-aware wearable systems, highlighting current trends, shortcomings, and challenges, and proposes a generic reference architecture to promote the development of next-generation WCS.
IEEE SENSORS JOURNAL
(2022)
Review
Engineering, Electrical & Electronic
Santanu Kumar Behera
Summary: Radio frequency identification (RFID) technology has a wide range of applications in automatic identification, tracking, and security investigation. Wearable sensors using chipless RFID tags enable real-time monitoring of vital signs. Chipless tag sensors are a cost-effective and maintenance-free alternative to traditional RFID sensors, fulfilling the requirements of emerging technologies.
IEEE SENSORS JOURNAL
(2022)
Article
Engineering, Electrical & Electronic
Zewei Pan, Huigang Gao, Yan Chen, Zekun Xie, Longhan Xie
Summary: Using inertial measurement units (IMUs) and plantar pressure insole sensors for gait quantitative assessment allows for objective evaluation, reduced difficulty, and decreased reliance on doctors in rehabilitation plans. Experimental results show that the wearable device has good accuracy and data repeatability for gait assessment. The linear correlation between the extracted distance score and the Mini-BES test score is -0.94. Therefore, it is feasible to use wearable devices to evaluate lower limb rehabilitation through a walking test, potentially replacing the complex Mini-BES test.
IEEE SENSORS JOURNAL
(2023)
Review
Engineering, Electrical & Electronic
Anthony Palumbo, Zheqi Li, Eui-Hyeok Yang
Summary: Flexible and wearable sensors are gaining attention for their lightweight, portable, wearable, or implantable capabilities. Carbon nanotube-based flexible sensors show promise in detecting diverse chemical species and mechanical forces, withstanding various mechanical loads while maintaining stable detections.
IEEE SENSORS JOURNAL
(2022)
Article
Chemistry, Physical
Thao Nguyen, Michael Chu, Robin Tu, Michelle Khine
Summary: Encapsulation is introduced to improve the stretchability, linear response, and robustness of soft strain sensors, making them more adaptable to body movement with increased mechanical robustness and stability.
Article
Engineering, Electrical & Electronic
R. Atoche-Ensenat, E. Perez, A. Hernandez-Benitez, A. Balam, Johan J. Estrada-Lopez, J. Vazquez-Castillo, F. Aviles, A. Castillo-Atoche
Summary: Recent advances in nanomaterials enable the fabrication of tactile sensors suitable for electronic skin, haptic interfaces, and biomedical applications. The problem of complex inertial measurements during the tactile process of polymer composites can be solved using artificial intelligence (AI). However, implementing AI-based signal processing on embedded devices is still an untapped opportunity for designing the next generation of smart wearable sensor systems. This study proposes a novel nanostructured smart tactile sensing system for wearable applications, utilizing a 3-D-printed structure with embedded electronic devices. The integration of electronic circuits for signal processing of an artificial neural network (NN) on a digital controller unit improves tactile interpretation in the wearable embedded device. Experimental results demonstrate 98% accuracy in pressure classification on MWCNT/PP composites.
IEEE SENSORS JOURNAL
(2023)
Article
Engineering, Electrical & Electronic
Baichen Li, R. Scott Downen, Quan Dong, Nam Tran, Maxine LeSaux, Andrew C. Meltzer, Zhenyu Li
Summary: This study introduces a novel transdermal alcohol sensor that can be worn discreetly to monitor alcohol concentration in sweat. Preliminary data shows the sensor's effectiveness in monitoring low doses of alcohol, however, significant variability was observed in measurements under less controlled conditions, suggesting further research is needed to understand the impact of perspiration rates on the sensor's accuracy and reproducibility.
IEEE SENSORS JOURNAL
(2021)
Article
Computer Science, Information Systems
Muhammad A. Butt, Nikolay L. Kazanskiy, Svetlana N. Khonina
Summary: Technological innovation has greatly impacted our lives and well-being, with wearable sensing tools being an important and rapidly growing sector. This paper discusses the recent advancements in wearable electronics for temperature and pressure sensing applications.
Article
Pharmacology & Pharmacy
Steffi Augustine, Bala Prabhakar, Pravin Shende
Summary: This study successfully developed an oxidized graphene nanoribbons (O-GNRs)-based delivery system for cisplatin against non-small cell lung carcinoma. The nanosized strips of graphene exhibited high drug loading capacity and controlled release. The nanoformulation showed promising inhibition rate on the lung cancer cell line through passive targeting. Graphene-based systems have great potential in cancer treatment due to their additive effect with therapeutic agents.
CURRENT DRUG DELIVERY
(2022)
Review
Biochemistry & Molecular Biology
Riddhi Trivedi, Pravin Shende
Summary: Nanotechnology in the food sector offers various applications and advantages in terms of health improvement and alternative medicine. With further advances in technology and proper regulations, nanofood holds the potential for safety and long-term stability.
CURRENT PHARMACEUTICAL BIOTECHNOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Priyank Shah, Pravin Shende
Summary: Female reproductive tract cancers pose significant challenges to reproductive health. Traditional treatment methods have limitations and side effects. Utilizing sperm-based drug delivery systems can improve targeting and control, providing new solutions for treating these cancers.
CURRENT PHARMACEUTICAL BIOTECHNOLOGY
(2022)
Review
Pharmacology & Pharmacy
Pravin Shende, Shubham Gupta
Summary: This review article discusses the recent developments in the use of lipopolysaccharides (LPS) in nanocarrier systems for various applications such as vaccination, cancer chemotherapy, and immune stimulation. The article highlights how different nanocarriers, including cubosomes, niosomes, dendrimers, and metal nanoparticles, are used to decorate LPS molecules, enhancing the effectiveness of molecules in cancer immunotherapy. The use of LPS-decorated nanoparticles also improves overall immunogenic response and effectiveness in vaccine immunotherapy and targeted therapy, with potential applications in human, poultry, and aquaculture settings.
CURRENT PHARMACEUTICAL DESIGN
(2022)
Review
Pharmacology & Pharmacy
Vasavi Basarkar, Sharayu Govardhane, Pravin Shende
Summary: Genetically modified micro-organisms have shown better efficacy and targeted delivery in healthcare, particularly in the treatment of cancer, obesity, and HIV infection. Modifying micro-organisms and integrating different therapeutic fragments have enhanced their therapeutic activity. Genetically modified micro-organisms also have diverse applications in various sectors, such as electricity generation and water purification.
CURRENT PHARMACEUTICAL DESIGN
(2022)
Review
Materials Science, Biomaterials
Maitri Bhatt, Pravin Shende
Summary: This review article provides an overview of the existing advances in protein patterning technology, focusing on physical and physicochemical methods. It discusses different protein patterning approaches and their design methods, as well as chemical modification and analytical methods for protein functionality evaluation. The article also explores the topographical effects of patterning techniques on protein functionalization and orientation. Future applications include high-throughput screening, evaluation of intracellular interactions, accurate screening, and personalized treatments.
JOURNAL OF MATERIALS CHEMISTRY B
(2022)
Article
Materials Science, Biomaterials
Mihir S. Lukhey, Pravin Shende
Summary: In recent years, due to advances in molecular biology, researchers have gained a better understanding of the etiology of acute and chronic wounds, leading to the development of innovative therapies. This study focuses on the use of nano-structural formulations for the healing of infectious wounds, discussing the factors that influence the functionalization of nanocarriers.
INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS
(2023)
Article
Chemistry, Physical
Nazneen Pathan, Pravin Shende
Summary: Graphene nanoribbons, as thin sheets with unique characteristics, have potential applications in drug delivery and cancer treatment. In this research, carboxyl-functionalized oxidized graphene nanoribbons adsorbing metformin were developed for the treatment of oral cancer using photo-thermal radiation therapy. The nanoribbons were characterized and evaluated for drug release and cytotoxicity. The study showed enhanced drug release in acidic pH with photothermal radiation, as well as higher inhibition of cancer cells at lower drug concentration and with photothermal therapy compared to plain drug. Graphene's characteristics were utilized to develop a targeted drug delivery system against oral cancer cells.
PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION
(2023)
Review
Chemistry, Physical
Kalyani Kharangate, Pravin Shende
Summary: Hybrid dendrimers with complex architecture and diverse functional groups have been developed for drug delivery and imaging applications. These smart dendrimers exhibit desirable properties such as improved surface area, monodisperse behavior, enhanced stability, and reduced toxicity. They can be used to encapsulate various drugs, nucleic acids, and diagnostic agents, and have shown potential in treating conditions such as glaucoma, inflammation, microbial infection, neurodegenerative diseases, and cancer. Advancements in molecular engineering techniques and other technologies have facilitated the development of economically reliable and personalized pharmaceutical hybrid dendritic systems.
PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION
(2023)
Review
Pharmacology & Pharmacy
Kadambari Borse, Pravin Shende
Summary: 3D printing is an advanced technique for manufacturing drugs, while 4D printing is a further development that allows printed objects to change shape in response to stimuli. 4D printing offers greater printing capacity, higher manufacturing efficiency, improved quality, lower production costs, and the ability to produce a wider range of products.
Article
Chemistry, Multidisciplinary
Shweta Mishra, Khushwant S. Yadav, Bala Prabhakar
Summary: Nanocrystalline cellulose, with its unique physical and biological properties, has gained attention from researchers. The utilization of agricultural waste, such as sugarcane bagasse and banana peels, for the production of nanocrystalline cellulose can help protect the environment. Researchers optimized the concentration of these nanocrystalline cellulose materials as disintegrants in the preparation of Diclofenac potassium IR tablets. The tablets showed promising results and can be explored as a new disintegrant for solid oral dosage forms.
Article
Chemistry, Physical
Priyank Shah, Pravin Shende
Summary: This study focuses on the controlled release of Quercetin from layered nanocarriers for improved stability and anti-diabetic activity. The optimized nanocarriers showed high entrapment efficiency and release of Quercetin. In vivo experiments demonstrated the significant controlled release of Quercetin for modulating blood glucose levels.
PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION
(2023)
Review
Toxicology
Maithili Kantak, Pravin Shende
Summary: The proof-of-concept of nanomaterials (NMs) in the fields of imaging, diagnosis, treatment, and theranostics shows their importance in biopharmaceuticals development. However, biotransformation and recyclable techniques of NMs in the human body are not well explored due to their small structures and cytotoxic effects. Recycling of NMs offers advantages such as dose reduction, re-utilization of therapeutics, and decrease in nanotoxicity, and approaches like in-vivo re-processing and bio-recycling are essential to overcome toxicities. Consideration of NMs' life-cycle in nanotherapeutics development is crucial for site-specific delivery, dose reduction, and other applications.
TOXICOLOGY RESEARCH
(2023)
Article
Biotechnology & Applied Microbiology
Piyush Verma, Rishi Kumar Singh, Anubhav Wadhwa, Bala Prabhakar, Khushwant S. Yadav
Summary: This study developed liposomes and solid lipid nanoparticles for the delivery of Bimatoprost, a drug used to lower intraocular pressure in glaucoma treatment. The optimized liposomes showed better encapsulation efficiency and drug kinetics compared to solid lipid nanoparticles, and when loaded in a thermo-sensitive hydrogel, they effectively decreased intraocular pressure for 18 hours.
Review
Biochemistry & Molecular Biology
Parth Mehta, Pravin Shende
Summary: This review article explores surface modification techniques and biological camouflage strategies to overcome the limitations of controlled drug release from nanoformulations due to opsonization. It highlights the potential of these approaches to develop next-generation nanoplatforms with long-circulating properties and superior therapeutic outcomes.
CELL BIOCHEMISTRY AND FUNCTION
(2023)
Review
Chemistry, Analytical
Claudia Campanale, Silvia Galafassi, Francesca Di Pippo, Iulian Pojar, Carmine Massarelli, Vito Felice Uricchio
Summary: Biodegradable plastic mulches (BDMs) have the potential to be an eco-friendly alternative to conventional plastic mulches in agriculture. However, their long-term impacts on soil ecosystems are still uncertain, and further research is needed. Incorporating BDMs into the soil may stimulate microbial activity, but there is also a risk of incomplete degradation and release of residual microplastics and additives.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Xuechi Yin, Sijie Liu, Deepak Kukkar, Jianlong Wang, Daohong Zhang, Ki-Hyun Kim
Summary: The lateral flow immunoassay strip is a classic and dominant tool in point-of-care detection, known for its portability and simplicity. However, current colored nanomaterials used as signal labels in LFIA have limited sensing potential, leading to the recognition of composite nanoparticles as alternatives to enhance sensitivity, signal readout diversity, anti-matrix interference, and cost-effectiveness.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Yaxin Cao, Longyi Shao, Timothy P. Jones, Wenjing Deng, M. Santosh, Pengju Liu, Cheng-Xue Yang, Yaowei Li, Daizhou Zhang, Kelly Berube
Summary: The toxicity of fibrous particles in ambient air can be higher than other types of particles. Microfibers can be organic or inorganic and their presence in the atmosphere as a result of human activity raises concerns for environmental and public health. Accurate collection, identification, and understanding of the health hazards associated with these fibers are crucial for mitigation strategies and protection of public health.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Chenchen Xie, Chen Meng, Huilin Liu, Baoguo Sun
Summary: The development of food hazard factor (FHF) detection has been moving towards on-site inspection and mobile law enforcement, calling for simple, fast, and affordable analysis technology to ensure food safety and quality. This review comprehensively summarizes the progress in research on smartphone-assisted MIP optosensors, focusing on the key issues of accuracy and sensitivity.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Guillem Peris-Pastor, Cristian Azorin, Jose Grau, Juan L. Benede, Alberto Chisvert
Summary: Green Analytical Chemistry plays an important role in every stage of method development, including sample preparation. Extraction techniques have evolved from conventional ones to a variety of miniaturized techniques in order to enhance analytical performance and ensure safety for operators and the environment. Green metric tools are used to evaluate the impact and sustainability of methods, with AGREEprep selected as the most suitable tool for evaluating published methods in various applications. The miniaturization of sample preparation strategies has led to the use of less and safer solvents, reduced waste generation and energy consumption, and improved portability and throughput.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Helena Hruskova, Roman Reminek, Frantisek Foret
Summary: This review article summarizes the progress and recent studies in offline electromigration preparative techniques between 2018 and 2023. It covers various techniques including electrophoresis, free-flow electrophoresis, isoelectric focusing, and isotachophoresis, providing theoretical aspects, trends, and solutions to existing limitations in each technique.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Mayank Garg, Nicole Pamme
Summary: This review focuses on the removal strategies of templates from molecularly imprinted polymers (MIPs) used in diagnostic biosensors. Chemical-based and electrochemical-based template extraction approaches are summarized and evaluated, providing guidance for researchers in the fields of analytical chemistry, diagnostics, and materials science for the design of MIP-based sensors.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Ivneet Banga, Anirban Paul, Nathan Kodjo Mintah Churcher, Ruchita Mahesh Kumar, Sriram Muthukumar, Shalini Prasad
Summary: Breathomics is an emerging field that focuses on analyzing exhaled breath to diagnose and monitor respiratory diseases. Electrochemical sensors, with their high sensitivity, selectivity, and low cost, play a significant role in breathomics and can be integrated into portable devices for point-of-care diagnosis.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Fabjola Bilo, Paola Cirelli, Laura Borgese
Summary: This review explores the application of X-ray fluorescence (XRF) spectrometry for elemental analysis of particulate matter (PM) in air quality monitoring. It discusses the fundamentals of XRF, experimental configurations, PM sampling devices and substrate, sample preparation strategies, qualitative and quantitative analysis, as well as the challenges faced by XRF in becoming a reliable analytical technique for PM analysis.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Hakim Faraji
Summary: The dispersive liquid-liquid microextraction (DLLME) technique is widely popular in analytical chemistry due to its high efficiency, cost-effectiveness, and simplicity. Recent advancements have addressed the limitations of DLLME, incorporating greener solvents, innovative dispersion strategies, and simplified procedures. These changes have made DLLME a more sustainable and efficient technique.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Sherin F. Hammad, Inas A. Abdallah, Alaa Bedair, Reda M. Abdelhameed, Marcello Locatelli, Fotouh R. Mansour
Summary: Carbon nanomaterials (CNMs) have excellent capabilities in terms of adsorption, enhanced oxidation, and photocatalysis, attracting widespread attention in different fields. Metal-organic frameworks (MOFs) have been widely used due to their regular network structure, porous nature, and large specific surface area. However, the instability of MOFs in aqueous solutions limits their applications in chemical sensing. Recent studies have focused on increasing the stability of MOFs in water-based matrices through chemical modifications using CNMs.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Alexandra Pape, Oliver J. Schmitz
Summary: Low temperature plasmas based on dielectric barrier discharges have emerged as a recent development in ion source research. These ion sources are applicable to heat-sensitive analytes and can ionize a wide range of compounds. Despite intensive research on important parameters such as configuration, shape, size, and materials in the past two decades, the actual ionization mechanism for all plasma gases has not been fully elucidated. This review provides an overview of atmospheric pressure ion sources, with a focus on plasma and dielectric barrier discharge based ion sources, summarizing the reactions occurring in the plasma and discussing the applications developed by different research groups.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Hai Xiong, Fengli Li, Linyu Zeng, Qiyu Lei
Summary: This review provides an overview of the emerging trends in the use of functional COF nanomaterials as biosensors for DNA/RNA detection. It summarizes the construction of DNA/RNA hybridized COF nanoprobes and their potential applications in bioanalyte detection, biosensing, biomarker imaging, and clinical biomedicine.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Bing Yan
Summary: This article summarizes the recent progress in logic gate computing and operation based on multiple luminescence response and chemical sensing for lanthanide functionalized MOF hybrid systems. The article first describes multi-color luminescence and the subsequent multiple luminescence response. The basic concept of logic gate operation and the advantages of lanthanide-based hybrid materials are then introduced. Reports on logic gate operation using pure lanthanide MOFs are provided, followed by a detailed summary of logic gate operations using lanthanide functionalized MOF hybrid materials. Additionally, the article discusses the practical luminescent detection of analytes by correlating the luminescence responsive signals and the concentration of different analytes. Finally, the article concludes with a prospect for this topic.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)
Review
Chemistry, Analytical
Brij Mohan, Gurjaspreet Singh, Rakesh Kumar Gupta, Pawan Kumar Sharma, Alexander A. Solovev, Armando J. L. Pombeiro, Peng Ren
Summary: Porous materials, particularly hydrogen-bonded organic frameworks (HOFs), have gained significant attention due to their versatile applications and unique properties such as well-defined crystalline structure and easy regeneration processes. This article provides a comprehensive overview of HOFs, including synthesis methods, hydrogen bonding motifs, recent advancements, and potential applications, offering valuable guidance for further exploration in this dynamic field.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2024)